Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 132646..134368 Replicon plasmid 1
Accession NZ_AP018682
Organism Vibrio casei strain DSM 22364

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag VCASEI_RS19120 Protein ID WP_089110661.1
Coordinates 132646..133584 (-) Length 313 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag VCASEI_RS19125 Protein ID WP_089110662.1
Coordinates 133577..134368 (-) Length 264 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VCASEI_RS19105 128083..128658 + 576 WP_089110658.1 DUF2913 family protein -
VCASEI_RS19110 128655..129398 - 744 WP_089110659.1 M48 family metallopeptidase -
VCASEI_RS19115 129421..132618 - 3198 WP_089110660.1 type I restriction endonuclease subunit R -
VCASEI_RS19120 132646..133584 - 939 WP_089110661.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
VCASEI_RS19125 133577..134368 - 792 WP_089110662.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
VCASEI_RS19130 134492..135547 - 1056 WP_089110663.1 Fic family protein -
VCASEI_RS19135 135549..136808 - 1260 WP_089110664.1 restriction endonuclease subunit S -
VCASEI_RS19140 136801..138567 - 1767 WP_089110665.1 type I restriction-modification system subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..160294 160294


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-279)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-96)


Sequences

Toxin        


Download         Length: 313 a.a.        Molecular weight: 35651.84 Da        Isoelectric Point: 4.7492

>T31969 WP_089110661.1 NZ_AP018682:c133584-132646 [Vibrio casei]
MDRNSPYYKQVSLLIRMLPIVATEPCFALKGGTAINLFVWDFPRLSVDIDLAYLPLEPRDEALANVKAALQRIVDIINTQ
SGIKAVYQDNRADELRIIVSTPSATIKIEVSPVSRGTLHSAEITPIKETVEDEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVRMLLNSDGISRDIFVGFLTYLLGHPRPINEVMNPNWQLLDERFQSEFDGMTFEPVTLEELTSARTEMLRALQK
QFTDKDRAFLLSYKEGAPDWSLFDYPDIANLPAIRWKLQNIEKLARNQDKHLEQVAKLERVLDEWLKQSSQQ

Download         Length: 939 bp

>T31969 NZ_AP018682:c133584-132646 [Vibrio casei]
ATGGATAGAAATAGCCCGTACTATAAGCAGGTTTCACTGCTCATTCGAATGCTACCCATTGTCGCAACGGAACCTTGTTT
TGCTTTGAAAGGTGGTACGGCGATTAATTTGTTTGTGTGGGATTTTCCTCGCTTGTCGGTGGATATCGATCTTGCTTACT
TGCCACTAGAGCCAAGAGATGAAGCCCTAGCCAATGTAAAAGCAGCACTGCAACGTATTGTAGATATCATTAATACTCAA
TCAGGGATTAAAGCCGTTTATCAAGATAACCGAGCCGATGAGCTTAGGATCATAGTTTCTACACCAAGTGCGACGATTAA
AATTGAAGTTTCCCCTGTTTCTAGAGGTACTTTACATTCTGCTGAAATAACTCCAATCAAAGAAACGGTAGAAGATGAAT
TTGGCTATGCAGAAATCCCTGTTGTTAGCCTTCCTGATTTATATGGTGGCAAACTTTGTGCAGCGATGGATCGACAACAT
CCTAGGGATCTATTTGATGTGCGTATGTTGCTGAACTCTGACGGGATTTCTCGTGATATTTTTGTTGGATTCTTAACGTA
TTTACTCGGTCATCCAAGGCCAATTAACGAAGTGATGAATCCAAACTGGCAGTTGCTTGATGAAAGGTTTCAATCTGAGT
TTGATGGCATGACATTTGAACCTGTTACGCTTGAAGAATTAACGTCTGCTCGCACTGAGATGTTACGCGCACTACAAAAA
CAGTTTACGGATAAAGATCGTGCCTTTTTGCTGTCCTATAAGGAAGGGGCTCCTGATTGGTCTTTGTTTGATTATCCTGA
TATAGCAAACCTGCCAGCGATTCGTTGGAAATTACAAAATATAGAGAAGTTAGCAAGAAACCAGGATAAGCATTTAGAGC
AAGTAGCAAAATTAGAACGGGTACTTGATGAGTGGTTGAAGCAATCAAGCCAGCAATAA

Antitoxin


Download         Length: 264 a.a.        Molecular weight: 29772.12 Da        Isoelectric Point: 8.8141

>AT31969 WP_089110662.1 NZ_AP018682:c134368-133577 [Vibrio casei]
MSSKINWLVSHTSPSSIVLLPWLLEHGIGYSLAQKYAKSGWLKRLASGVYYRPDARNDALPTWVEALHALNSQLQLPVHL
AGLSSLTHQGLSHYLPVSKEQVWLGVEQKADLPKWFREFDSSSWSYCTNTKLELMAEKDLKTITVQGQEIKASCPELAAY
EVVDAIGKLISFEHAAELLQGLVNLSPRKVQSLLERSDAIQANRIFLFLSHYHGHQWVKRLDESKIKLGSGKRQVVEGGR
YDERYKITVPMTLDISKKEQDYG

Download         Length: 792 bp

>AT31969 NZ_AP018682:c134368-133577 [Vibrio casei]
ATGTCATCAAAAATAAACTGGCTAGTGTCACATACCTCTCCGTCTTCTATCGTGTTGTTGCCTTGGTTGCTTGAGCACGG
TATCGGTTATTCTTTGGCTCAAAAATATGCAAAAAGTGGTTGGTTAAAGCGGTTAGCTTCGGGGGTTTACTACCGTCCAG
ATGCTAGAAATGATGCTTTACCAACTTGGGTTGAAGCCTTACACGCGTTAAATAGCCAATTACAACTTCCTGTTCATTTA
GCAGGACTAAGCAGTTTAACGCACCAAGGTTTAAGTCATTATTTGCCAGTATCGAAAGAGCAAGTTTGGTTAGGGGTTGA
ACAAAAAGCTGATCTTCCTAAATGGTTTAGAGAGTTTGATTCATCATCCTGGTCGTATTGCACAAATACAAAGCTTGAGT
TAATGGCTGAAAAAGATCTCAAAACCATAACGGTACAAGGTCAAGAGATTAAGGCCAGTTGTCCTGAACTGGCTGCTTAT
GAAGTGGTGGATGCGATAGGCAAATTAATCTCTTTTGAGCATGCGGCAGAACTCCTCCAAGGTTTAGTCAATTTAAGTCC
TAGAAAAGTACAATCTCTTCTTGAGCGTAGTGATGCTATACAAGCAAACCGTATTTTCTTGTTCTTGAGCCATTATCACG
GACATCAATGGGTGAAACGGTTAGATGAAAGCAAGATAAAACTAGGCTCGGGGAAACGACAAGTTGTTGAAGGTGGGCGC
TATGATGAGCGTTACAAAATCACGGTTCCAATGACTTTAGATATATCAAAAAAAGAGCAAGATTATGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References