Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2068468..2068613 Replicon chromosome
Accession NZ_AP018671
Organism Klebsiella pneumoniae strain GSU10-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2068504..2068606 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2068468..2068613 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D6O76_RS10480 2063598..2065658 + 2061 WP_110437850.1 oligopeptidase B -
D6O76_RS10485 2065662..2066321 - 660 WP_002911407.1 exodeoxyribonuclease X -
D6O76_RS10490 2066400..2066630 - 231 WP_002911406.1 DNA polymerase III subunit theta -
D6O76_RS10495 2066743..2067117 + 375 WP_004151448.1 CopC domain-containing protein YobA -
D6O76_RS10500 2067121..2067990 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
D6O76_RS10505 2068007..2068345 + 339 WP_002911404.1 YebY family protein -
- 2068468..2068613 - 146 - - Antitoxin
- 2068504..2068606 + 103 - - Toxin
D6O76_RS30240 2068981..2069124 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
D6O76_RS10515 2069229..2070197 - 969 WP_004151446.1 VirK/YbjX family protein -
D6O76_RS10520 2070354..2071007 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
D6O76_RS10525 2071004..2071195 - 192 WP_002911395.1 YebW family protein -
D6O76_RS10530 2071293..2071532 - 240 WP_002911393.1 YebV family protein -
D6O76_RS10535 2071648..2073081 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T31930 NZ_AP018671:2068504-2068606 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT31930 NZ_AP018671:c2068613-2068468 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References