Detailed information of TA system TA031922

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 1253316..1253853
• Replicon: chromosome
• Accession: NZ_AP018664
• Organism: Sphingobium amiense strain DSM 16289

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: SAMIE_RS05975
• Protein ID: WP_013846902.1
• Coordinates: 1253316..1253612 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: SAMIE_RS05980
• Protein ID: WP_013846901.1
• Coordinates: 1253602..1253853 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAMIE_RS05975	1253316..1253612	-	297	WP_013846902.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SAMIE_RS05980	1253602..1253853	-	252	WP_013846901.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
SAMIE_RS05985	1254080..1254556	+	477	WP_013846900.1	hypothetical protein	-
SAMIE_RS05990	1254553..1254858	+	306	WP_013846899.1	hypothetical protein	-
SAMIE_RS05995	1255046..1256293	+	1248	WP_013846898.1	hypothetical protein	-
SAMIE_RS06000	1256460..1257269	+	810	WP_013846897.1	type I restriction-modification system subunit M	-
SAMIE_RS06005	1257411..1258106	+	696	WP_013846896.1	hypothetical protein	-
SAMIE_RS06010	1258182..1258829	+	648	WP_013846895.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-91)

Antitoxin

• Antitoxin ParD (6-75)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10941.43 Da
• Isoelectric Point: 6.8785

>T31922 WP_013846902.1 NZ_AP018664:c1253612-1253316 [Sphingobium amiense]
MAYRLTRNAEKDLIGIYVGGVGELGEAVAEKYQAGLHRVFGFLSDFPYSARARAEISPPVRAHPYKSHIVVYIIEGQDIL
ILGVRHGREDWQASDQLS

Nucleotide

• Length: 297 bp

>T31922 NZ_AP018664:c1253612-1253316 [Sphingobium amiense]
ATGGCCTATAGACTCACGCGTAACGCCGAAAAGGATCTCATCGGTATATATGTCGGCGGCGTCGGAGAATTAGGAGAAGC
CGTCGCGGAAAAATATCAGGCCGGTTTGCATCGGGTTTTTGGATTTCTCTCCGACTTTCCCTATTCGGCAAGAGCGCGCG
CGGAAATTTCACCACCGGTCCGGGCACATCCCTACAAGTCCCATATCGTCGTCTATATCATCGAAGGACAGGACATCCTG
ATCCTCGGCGTCCGTCATGGACGGGAAGACTGGCAGGCATCCGACCAGCTTTCCTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9230.40 Da
• Isoelectric Point: 5.8295

>AT31922 WP_013846901.1 NZ_AP018664:c1253853-1253602 [Sphingobium amiense]
MATMNVSLPDAMKEWVEGQAGTGRYSNASDYVRDLIRRDQERREKIAAMQTMVDESLASGISPNSIDDMMKEARRRAGVG
HGL

Nucleotide

• Length: 252 bp

>AT31922 NZ_AP018664:c1253853-1253602 [Sphingobium amiense]
ATGGCGACAATGAATGTTTCCCTCCCCGATGCGATGAAGGAATGGGTCGAAGGTCAGGCCGGGACAGGCAGATACAGCAA
TGCCAGCGATTATGTGCGCGACCTGATCCGTCGCGACCAGGAGCGGCGGGAGAAGATCGCAGCCATGCAGACCATGGTCG
ATGAGTCTCTCGCCTCCGGCATAAGTCCCAATTCCATCGATGACATGATGAAGGAAGCCCGGCGTCGCGCAGGCGTCGGT
CATGGCCTATAG