Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 2120793..2121269 Replicon chromosome
Accession NZ_AP018587
Organism Staphylococcus caprae strain JMUB898

Toxin (Protein)


Gene name TsaT Uniprot ID C5QQH5
Locus tag JMUB898_RS10195 Protein ID WP_002441631.1
Coordinates 2121081..2121269 (+) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID C5QQH6
Locus tag JMUB898_RS10190 Protein ID WP_002441634.1
Coordinates 2120793..2121050 (+) Length 86 a.a.

Genomic Context

JMUB898_RS10160JMUB898_RS10165JMUB898_RS10170JMUB898_RS10180JMUB898_RS10190JMUB898_RS10195JMUB898_RS10200JMUB898_RS10215JMUB898_RS10220JMUB898_RS10225JMUB898_RS10230JMUB898_RS10155JMUB898_RS10175JMUB898_RS10185JMUB898_RS10205JMUB898_RS10210
Location: 2116908..2117330 (423 bp)
Type: Others
Protein ID: WP_002441647.1
Location: 2117725..2118231 (507 bp)
Type: Others
Protein ID: WP_002441644.1
Location: 2118429..2119049 (621 bp)
Type: Others
Protein ID: WP_002441642.1
Location: 2119919..2120155 (237 bp)
Type: Others
Protein ID: WP_002441638.1
Location: 2120793..2121050 (258 bp)
Type: Antitoxin
Protein ID: WP_002441634.1
Location: 2121081..2121269 (189 bp)
Type: Toxin
Protein ID: WP_002441631.1
Location: 2121495..2122079 (585 bp)
Type: Others
Protein ID: WP_037541212.1
Location: 2123304..2124050 (747 bp)
Type: Others
Protein ID: WP_044466334.1
Location: 2124171..2124455 (285 bp)
Type: Others
Protein ID: WP_002441619.1
Location: 2124484..2124702 (219 bp)
Type: Others
Protein ID: WP_002441617.1
Location: 2125004..2125330 (327 bp)
Type: Others
Protein ID: WP_002441615.1
Location: 2116016..2116738 (723 bp)
Type: Others
Protein ID: WP_002441649.1
Location: 2119111..2119695 (585 bp)
Type: Others
Protein ID: WP_037541214.1
Location: 2120147..2120350 (204 bp)
Type: Others
Protein ID: WP_002441635.1
Location: 2122143..2122376 (234 bp)
Type: Others
Protein ID: WP_002441627.1
Location: 2122518..2123123 (606 bp)
Type: Others
Protein ID: WP_002441625.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JMUB898_RS101552116016..2116738-723WP_002441649.1type I 3-dehydroquinate dehydratase-
JMUB898_RS101602116908..2117330+423WP_002441647.1organic hydroperoxide resistance protein-
JMUB898_RS101652117725..2118231+507WP_002441644.1GNAT family N-acetyltransferase-
JMUB898_RS101702118429..2119049+621WP_002441642.1LysE family transporter-
JMUB898_RS101752119111..2119695-585WP_037541214.1phosphoglycerate mutase family protein-
JMUB898_RS101802119919..2120155+237WP_002441638.1hypothetical protein-
JMUB898_RS101852120147..2120350-204WP_002441635.1sterile alpha motif-like domain-containing protein-
JMUB898_RS101902120793..2121050+258WP_002441634.1hypothetical proteinAntitoxin
JMUB898_RS101952121081..2121269+189WP_002441631.1hypothetical proteinToxin
JMUB898_RS102002121495..2122079+585WP_037541212.1orthopoxovirus protein, PF05708 family-
JMUB898_RS102052122143..2122376-234WP_002441627.1hypothetical protein-
JMUB898_RS102102122518..2123123-606WP_002441625.1GNAT family N-acetyltransferase-
JMUB898_RS102152123304..2124050+747WP_044466334.1poly-gamma-glutamate hydrolase family protein-
JMUB898_RS102202124171..2124455+285WP_002441619.1hypothetical protein-
JMUB898_RS102252124484..2124702+219WP_002441617.1hypothetical protein-
JMUB898_RS102302125004..2125330+327WP_002441615.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(5-57)

Antitoxin

Cro/C1-type helix-turn-helix domain

(88-134)


Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7214.94 Da        Isoelectric Point: 9.7844

>T31920 WP_002441631.1 NZ_AP018587:2121081-2121269 [Staphylococcus caprae]
MNLHFQILLWLSIIFIVAGAIILAIMLKTKKEERKESYLGFTVIFLIFGFAMLIYTFIFGIL

Download         Length: 189 bp

>T31920 NZ_AP018587:2121081-2121269 [Staphylococcus caprae]
ATGAATTTACATTTTCAAATATTATTATGGCTTTCAATTATATTCATTGTTGCTGGTGCAATTATTTTAGCCATTATGCT
TAAAACGAAAAAAGAAGAGAGAAAAGAATCTTATTTAGGTTTTACGGTTATTTTCTTAATTTTCGGCTTTGCAATGCTCA
TTTATACATTTATTTTTGGTATATTATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9735.80 Da        Isoelectric Point: 4.0612

>AT31920 WP_002441634.1 NZ_AP018587:2120793-2121050 [Staphylococcus caprae]
MKIISVNVINIILTVLFIAFNVLITYNANVDNHLWLIPGLCICGIALFTSLTIAIIYTDLLSEILFFINIVLALYYIYPI
FYDFL

Download         Length: 258 bp

>AT31920 NZ_AP018587:2120793-2121050 [Staphylococcus caprae]
ATGAAAATAATTAGTGTAAATGTGATTAATATCATCTTAACCGTACTATTTATAGCTTTTAATGTACTCATTACCTATAA
TGCAAACGTTGATAATCACCTATGGTTAATACCAGGATTATGTATTTGTGGTATTGCTCTATTTACGAGTTTAACAATAG
CAATTATTTATACTGATCTTTTAAGTGAAATTTTGTTCTTTATTAATATTGTCTTAGCACTTTACTATATTTATCCAATT
TTTTATGACTTCCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1S1GRH8

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1S1GRF3

References