Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2646276..2646952 Replicon chromosome
Accession NZ_AP018560
Organism Aerosticca soli strain Dysh456

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ALSL_RS12535 Protein ID WP_198410658.1
Coordinates 2646587..2646952 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ALSL_RS12530 Protein ID WP_126540262.1
Coordinates 2646276..2646479 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ALSL_RS12505 2642373..2642771 + 399 WP_198410698.1 FdtA/QdtA family cupin domain-containing protein -
ALSL_RS12510 2642768..2643568 + 801 WP_126539546.1 hypothetical protein -
ALSL_RS12515 2643670..2645076 - 1407 Protein_2432 IS5 family transposase -
ALSL_RS12520 2645392..2645673 + 282 WP_062196849.1 type II toxin-antitoxin system ParD family antitoxin -
ALSL_RS12525 2645670..2646020 + 351 WP_062196848.1 type II toxin-antitoxin system RelE/ParE family toxin -
ALSL_RS12530 2646276..2646479 + 204 WP_126540262.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ALSL_RS12535 2646587..2646952 + 366 WP_198410658.1 type II toxin-antitoxin system YafQ family toxin Toxin
ALSL_RS12540 2646937..2648007 - 1071 WP_126539550.1 alkene reductase -
ALSL_RS12545 2648160..2648342 + 183 WP_126539552.1 hypothetical protein -
ALSL_RS12550 2648393..2648587 + 195 WP_126539554.1 hypothetical protein -
ALSL_RS12555 2648602..2650233 - 1632 WP_126539556.1 MASE1 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-59)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-49)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13154.88 Da        Isoelectric Point: 7.3749

>T31894 WP_198410658.1 NZ_AP018560:2646587-2646952 [Aerosticca soli]
MLLLIGNDAPLSPEWLDHPLEGDWVDHRECHIGGDFLLIYRLDGNAIVFVRAGTHSELFEEGFRHAVTTCRCAAPSVGSG
PAGTGAGSYAMTGQRVLRSACAVAARKQRAHRQRRDLQSSV

Download         Length: 366 bp

>T31894 NZ_AP018560:2646587-2646952 [Aerosticca soli]
ATGCTGCTGCTCATTGGCAACGACGCGCCGCTGAGCCCCGAATGGCTGGACCACCCGCTCGAGGGCGATTGGGTAGACCA
CCGTGAATGCCACATCGGTGGCGACTTTCTTCTGATCTACCGCTTGGATGGAAACGCCATCGTCTTTGTGCGTGCGGGCA
CGCATTCTGAATTGTTCGAAGAAGGTTTCAGGCACGCCGTAACCACCTGCCGCTGCGCGGCCCCGTCAGTCGGCAGCGGC
CCCGCTGGAACCGGAGCTGGCTCATACGCCATGACCGGCCAGCGGGTTTTGCGATCCGCATGCGCCGTGGCAGCGCGCAA
GCAACGAGCTCACCGCCAACGGCGTGATCTTCAAAGCTCGGTATAA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7456.58 Da        Isoelectric Point: 8.6604

>AT31894 WP_126540262.1 NZ_AP018560:2646276-2646479 [Aerosticca soli]
MGLTVSDAVRILLKRVVNEQAFPLELKVPNAQTRAAMEEARAMAKARTARYDSADALIDDLEKARQQ

Download         Length: 204 bp

>AT31894 NZ_AP018560:2646276-2646479 [Aerosticca soli]
ATGGGGCTGACCGTGTCCGACGCTGTGCGCATCCTGCTCAAGCGCGTGGTGAACGAACAGGCCTTCCCGTTGGAGTTGAA
GGTGCCCAACGCCCAGACCCGCGCGGCGATGGAAGAAGCCCGCGCCATGGCCAAGGCGCGCACCGCCCGTTATGACTCCG
CCGATGCCCTGATCGATGACCTCGAAAAAGCCCGCCAGCAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References