Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1202135..1202913 Replicon chromosome
Accession NZ_AP018560
Organism Aerosticca soli strain Dysh456

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag ALSL_RS05605 Protein ID WP_126537238.1
Coordinates 1202135..1202638 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag ALSL_RS05610 Protein ID WP_126537240.1
Coordinates 1202635..1202913 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ALSL_RS05580 1199509..1200462 + 954 WP_126537232.1 EF-P lysine aminoacylase GenX -
ALSL_RS05585 1200539..1201012 + 474 WP_126537234.1 PepSY domain-containing protein -
ALSL_RS05590 1201031..1201597 + 567 WP_126537236.1 RNA 2',3'-cyclic phosphodiesterase -
ALSL_RS05595 1201789..1202075 - 287 Protein_1097 hypothetical protein -
ALSL_RS05605 1202135..1202638 - 504 WP_126537238.1 GNAT family N-acetyltransferase Toxin
ALSL_RS05610 1202635..1202913 - 279 WP_126537240.1 DUF1778 domain-containing protein Antitoxin
ALSL_RS05620 1203762..1204250 - 489 WP_126537242.1 SsrA-binding protein SmpB -
ALSL_RS05625 1204313..1204741 + 429 WP_126537244.1 type II toxin-antitoxin system RatA family toxin -
ALSL_RS05630 1204734..1205000 + 267 WP_126537246.1 RnfH family protein -
ALSL_RS05635 1205010..1205462 - 453 WP_126537248.1 outer membrane protein assembly factor BamE -
ALSL_RS05640 1205536..1205949 + 414 WP_126537250.1 ferric iron uptake transcriptional regulator -
ALSL_RS05645 1206193..1207791 - 1599 WP_126537252.1 MASE1 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-141)

Antitoxin

Vibrio phage ICP1, Orf50

(11-86)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18390.25 Da        Isoelectric Point: 8.1312

>T31893 WP_126537238.1 NZ_AP018560:c1202638-1202135 [Aerosticca soli]
MSNGYSPVRKLAATDQVDAFDCGQAALNQFLQRYALVNQKANSAQTYVCCQSDVVVGFYSLAVGSVDPEAAPARVMKGLA
RHPVPVMILARLAVDKAHQRKGLGQALLKDALLRTAQAADIAGIRCLLVHAKDDAARQWYEWWEFEPSPTDPYHLFLMLK
DLKGMLS

Download         Length: 504 bp

>T31893 NZ_AP018560:c1202638-1202135 [Aerosticca soli]
TTGAGCAATGGCTACTCACCCGTTCGAAAGCTGGCGGCGACGGATCAGGTCGATGCGTTCGACTGCGGCCAGGCCGCGCT
GAACCAGTTCCTGCAGCGCTACGCGCTCGTCAACCAGAAAGCCAACAGCGCGCAGACCTACGTCTGCTGCCAGAGCGACG
TGGTGGTCGGCTTCTACAGCCTCGCCGTCGGCAGTGTCGATCCGGAGGCCGCGCCGGCAAGAGTGATGAAGGGGCTGGCG
CGTCACCCGGTACCGGTCATGATCCTGGCCCGGCTCGCGGTGGACAAGGCGCATCAGCGCAAAGGTCTGGGCCAGGCCTT
GCTCAAGGATGCGCTGCTGCGCACCGCACAGGCCGCCGACATCGCCGGCATTCGCTGCCTGCTGGTCCATGCCAAGGACG
ATGCGGCGCGGCAGTGGTACGAATGGTGGGAATTCGAGCCCAGCCCGACTGACCCGTACCATCTGTTCCTGATGCTCAAG
GATCTCAAGGGCATGTTGAGCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10264.89 Da        Isoelectric Point: 10.3876

>AT31893 WP_126537240.1 NZ_AP018560:c1202913-1202635 [Aerosticca soli]
MSTLNLPKTERIDVRASTPVKQLLQEAARACHKNVSEFLLDAGVTAAAQTLADRRQFVLDEAQWQAFQEALDRPVKAKPR
LKKLLREPGVLG

Download         Length: 279 bp

>AT31893 NZ_AP018560:c1202913-1202635 [Aerosticca soli]
ATGAGCACCCTGAATCTTCCAAAAACCGAACGCATCGACGTTCGTGCCAGTACGCCGGTCAAGCAGCTGCTGCAGGAGGC
CGCGCGCGCCTGCCACAAGAACGTCAGCGAGTTCCTGCTCGACGCAGGCGTGACGGCAGCCGCGCAGACGCTGGCGGATC
GTCGCCAGTTCGTGCTCGACGAGGCGCAGTGGCAGGCGTTCCAGGAAGCGCTGGATCGGCCGGTAAAAGCCAAGCCGCGC
CTGAAAAAGTTGCTGCGTGAACCTGGGGTGCTGGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References