Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 395200..395861 Replicon chromosome
Accession NZ_AP018560
Organism Aerosticca soli strain Dysh456

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ALSL_RS01690 Protein ID WP_126536056.1
Coordinates 395433..395861 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ALSL_RS01685 Protein ID WP_126536054.1
Coordinates 395200..395433 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ALSL_RS01675 391317..391937 + 621 WP_126536050.1 plasmid pRiA4b ORF-3 family protein -
ALSL_RS01680 392089..395130 + 3042 WP_126536052.1 DEAD/DEAH box helicase family protein -
ALSL_RS01685 395200..395433 + 234 WP_126536054.1 DNA-binding protein Antitoxin
ALSL_RS01690 395433..395861 + 429 WP_126536056.1 type II toxin-antitoxin system VapC family toxin Toxin
ALSL_RS01695 395858..396007 + 150 WP_126536058.1 addiction module protein -
ALSL_RS01700 396125..398998 + 2874 WP_126536060.1 site-specific DNA-methyltransferase -
ALSL_RS01705 398995..399750 + 756 WP_126536062.1 TIGR04255 family protein -
ALSL_RS01710 399747..400256 + 510 WP_126536064.1 hypothetical protein -
ALSL_RS01715 400225..400644 + 420 WP_126536066.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15573.69 Da        Isoelectric Point: 4.3423

>T31891 WP_126536056.1 NZ_AP018560:395433-395861 [Aerosticca soli]
MYLLDTNVVSELRKGARANAGVIGFVERVASEDAPTYISVITLGELRRGVELIRHRGDLPQAEALESWLQVLLDDYADQI
LEFGAEEAQVWGRLRVPQPENALDKQIAATALTCGLTLVTRNLRDFAATGAPLLNPFEETPA

Download         Length: 429 bp

>T31891 NZ_AP018560:395433-395861 [Aerosticca soli]
ATGTATCTGCTCGACACCAACGTCGTCAGCGAGCTGCGCAAGGGTGCGCGCGCCAACGCTGGTGTCATCGGCTTCGTCGA
GCGCGTCGCGAGCGAAGACGCCCCGACCTACATCAGTGTCATCACGCTGGGCGAGCTGCGCCGCGGCGTCGAGCTGATTC
GCCACCGCGGCGACCTGCCGCAGGCCGAAGCGCTGGAAAGCTGGCTGCAAGTGCTGCTGGACGACTACGCCGATCAGATC
CTGGAGTTCGGTGCCGAGGAGGCCCAGGTGTGGGGCCGGCTGCGCGTGCCCCAGCCCGAGAACGCGCTCGACAAGCAGAT
CGCCGCCACTGCGCTCACCTGCGGGCTGACGCTGGTGACGCGCAATTTGCGCGACTTCGCCGCCACCGGCGCGCCCTTGC
TCAACCCCTTCGAGGAGACACCCGCATGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8807.04 Da        Isoelectric Point: 10.4369

>AT31891 WP_126536054.1 NZ_AP018560:395200-395433 [Aerosticca soli]
MANLIVRNVDDAIANALKQRASRHGISAEAEHRRILEQVLLRPRRKSFLEVLRQMPDVGRDEDFARQDGQPAAKVFD

Download         Length: 234 bp

>AT31891 NZ_AP018560:395200-395433 [Aerosticca soli]
ATGGCCAATCTGATCGTGCGCAATGTCGACGATGCCATCGCCAACGCGCTGAAACAGCGCGCGAGCCGCCACGGCATCAG
CGCCGAGGCCGAGCACCGCCGCATTCTGGAACAGGTGCTGCTGCGACCGCGCCGCAAATCCTTCCTCGAAGTGTTGCGCC
AGATGCCGGACGTCGGCCGCGACGAGGACTTCGCACGGCAGGATGGGCAGCCCGCAGCGAAGGTCTTCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References