Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 738988..739594 Replicon chromosome
Accession NZ_AP018553
Organism Sulfodiicoccus acidiphilus strain HS-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HS1genome_RS03880 Protein ID WP_126449696.1
Coordinates 738988..739380 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HS1genome_RS03885 Protein ID WP_126449697.1
Coordinates 739370..739594 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HS1genome_RS03845 (HS1genome_0752) 734450..734863 - 414 WP_126449692.1 hypothetical protein -
HS1genome_RS03850 (HS1genome_0753) 734918..735565 + 648 WP_126449693.1 hypothetical protein -
HS1genome_RS03855 (HS1genome_0754) 735562..736023 - 462 WP_126449694.1 DNA starvation/stationary phase protection protein -
HS1genome_RS03860 (HS1genome_0755) 736070..736873 - 804 WP_126449695.1 ParA family protein -
HS1genome_RS03865 737281..738237 + 957 Protein_754 IS5/IS1182 family transposase -
HS1genome_RS03880 (HS1genome_0760) 738988..739380 - 393 WP_126449696.1 type II toxin-antitoxin system VapC family toxin Toxin
HS1genome_RS03885 (HS1genome_0761) 739370..739594 - 225 WP_126449697.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
HS1genome_RS12530 740081..740173 - 93 WP_229768104.1 hypothetical protein -
HS1genome_RS03895 741261..741467 - 207 WP_126449698.1 sulfocyanin -
HS1genome_RS03900 (HS1genome_0762) 741604..741978 + 375 WP_126449699.1 hypothetical protein -
HS1genome_RS12535 742453..742599 - 147 Protein_760 transposase -
HS1genome_RS03905 (HS1genome_0763) 742905..743885 - 981 WP_126451303.1 pyridoxal-phosphate dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(23-118)

Antitoxin

Post-segregation antitoxin CcdA

(5-46)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 15118.72 Da        Isoelectric Point: 8.2638

>T31887 WP_126449696.1 NZ_AP018553:c739380-738988 [Sulfodiicoccus acidiphilus]
MKDREFLFDASALYSLLDYADKVDIKKIHILTLTFYEVGNAIWKEYYIHKKVKDPITLSKLFYELMRRFNVVDDPPLEGV
MRIAIERGLTYYDAAYAYVAESLGLILVSNDKELIRKANAISLKNLIKSM

Download         Length: 393 bp

>T31887 NZ_AP018553:c739380-738988 [Sulfodiicoccus acidiphilus]
ATGAAAGATAGGGAATTCCTATTCGATGCCTCAGCTTTATATTCGCTTTTAGATTACGCGGATAAAGTAGATATTAAGAA
AATTCACATACTCACCTTAACTTTTTATGAGGTAGGTAATGCTATATGGAAGGAGTATTATATACATAAGAAGGTTAAAG
ATCCTATAACACTTTCTAAACTTTTCTATGAATTAATGCGAAGGTTTAACGTAGTAGACGATCCGCCTCTTGAAGGGGTA
ATGAGAATTGCCATAGAAAGGGGTTTAACTTACTATGACGCGGCTTATGCATACGTTGCCGAATCTTTAGGGCTTATCCT
TGTATCTAACGATAAAGAGTTAATAAGAAAAGCTAATGCTATTTCGTTAAAGAATTTGATAAAAAGTATGTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8820.23 Da        Isoelectric Point: 4.8365

>AT31887 WP_126449697.1 NZ_AP018553:c739594-739370 [Sulfodiicoccus acidiphilus]
MSDVISVRVKKELKKKAEELGINIREVVEKALEESIMEKEKEELRDMAMKIKELMKDVSEDDWIRAVRESRDER

Download         Length: 225 bp

>AT31887 NZ_AP018553:c739594-739370 [Sulfodiicoccus acidiphilus]
ATGTCAGACGTAATAAGCGTAAGAGTTAAGAAAGAGCTAAAGAAGAAGGCAGAGGAGCTAGGAATTAATATTAGGGAAGT
TGTAGAAAAGGCACTAGAGGAATCAATAATGGAGAAGGAAAAGGAAGAGCTTAGGGATATGGCTATGAAAATTAAGGAAC
TAATGAAGGATGTAAGCGAAGATGATTGGATAAGGGCTGTTAGGGAGAGTAGGGATGAAAGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References