31886

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/AbrB(antitoxin)
Location 558533..559139 Replicon chromosome
Accession NZ_AP018553
Organism Sulfodiicoccus acidiphilus strain HS-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HS1genome_RS03020 Protein ID WP_229768172.1
Coordinates 558759..559139 (+) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HS1genome_RS03015 Protein ID WP_126449548.1
Coordinates 558533..558778 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HS1genome_RS11965 555049..555225 + 177 WP_158613705.1 hypothetical protein -
HS1genome_RS02995 (HS1genome_0577) 555296..555556 + 261 WP_126449540.1 hypothetical protein -
HS1genome_RS03000 (HS1genome_0578) 555713..556012 + 300 WP_126449542.1 winged helix-turn-helix domain-containing protein -
HS1genome_RS03005 (HS1genome_0579) 556009..556332 - 324 WP_158613706.1 winged helix-turn-helix domain-containing protein -
HS1genome_RS03010 (HS1genome_0580) 557435..557764 - 330 WP_126449546.1 hypothetical protein -
HS1genome_RS03015 (HS1genome_0581) 558533..558778 + 246 WP_126449548.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
HS1genome_RS03020 (HS1genome_0582) 558759..559139 + 381 WP_229768172.1 PIN domain-containing protein Toxin
HS1genome_RS03025 (HS1genome_0583) 559640..561829 + 2190 WP_126449550.1 glyceraldehyde dehydrogenase subunit alpha -
HS1genome_RS03030 (HS1genome_0584) 561863..563104 + 1242 WP_126449552.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-119)

Antitoxin

SpoVT-AbrB domain

(5-47)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 14542.77 Da        Isoelectric Point: 4.4420

>T31886 WP_229768172.1 NZ_AP018553:558759-559139 [Sulfodiicoccus acidiphilus]
MLEAVVDTNFVIAVMFKDHEYHERALIEWSKLEKAYLPLISITELAYFIINNKLNFELIDEVINDPKIEIVPETIDDVYC
ASSNNGEIKGYDDFNDFLILSVSVKLNLPLLTFDKKLKAKSDRSRV

Download         Length: 381 bp

>T31886 NZ_AP018553:558759-559139 [Sulfodiicoccus acidiphilus]
TTGCTAGAGGCGGTAGTTGATACTAATTTTGTAATAGCCGTTATGTTTAAAGATCACGAGTATCACGAGAGAGCGTTAAT
AGAATGGAGTAAACTCGAGAAGGCCTATTTACCGTTAATTTCCATTACAGAACTTGCCTATTTTATTATTAATAATAAGC
TAAATTTTGAGTTAATAGATGAAGTCATCAACGATCCCAAAATCGAGATAGTACCTGAGACTATAGATGACGTTTACTGT
GCCTCAAGTAATAATGGGGAGATAAAGGGTTATGATGACTTTAACGACTTTTTGATCTTATCAGTTTCGGTCAAGTTAAA
TTTACCTTTGCTTACATTTGACAAGAAGTTGAAAGCTAAAAGTGATAGAAGTCGAGTCTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9051.55 Da        Isoelectric Point: 10.2110

>AT31886 WP_126449548.1 NZ_AP018553:558533-558778 [Sulfodiicoccus acidiphilus]
VSVEVKVTRNYQITIPYEVRQKLSIKMGDKLIVKVEGDKIIIQKKRGDISSLNLTLGRKITDEEINDVINVAGREIARGG
S

Download         Length: 246 bp

>AT31886 NZ_AP018553:558533-558778 [Sulfodiicoccus acidiphilus]
GTGTCCGTGGAAGTAAAGGTAACTAGGAACTATCAGATAACGATACCTTACGAGGTTAGGCAAAAGTTGAGTATAAAAAT
GGGGGACAAGCTTATCGTGAAAGTGGAAGGCGATAAGATAATAATACAGAAGAAGAGGGGCGATATATCTTCTCTTAACC
TCACTTTGGGGAGGAAGATAACTGACGAGGAGATCAATGATGTAATAAACGTGGCTGGTAGGGAAATTGCTAGAGGCGGT
AGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References