Detailed information of TA system TA031844

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpAB/BrnT-BrnA
• Location: 889572..890196
• Replicon: chromosome
• Accession: NZ_AP018519
• Organism: Sphingobium sp. YG1

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: YGS_RS21120
• Protein ID: WP_037474511.1
• Coordinates: 889572..889880 (+)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: shpB
• Uniprot ID: -
• Locus tag: YGS_RS21125
• Protein ID: WP_197421464.1
• Coordinates: 889912..890196 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
YGS_RS21100	885764..887194	+	1431	WP_037474520.1	aldehyde dehydrogenase family protein	-
YGS_RS21105	887199..888776	+	1578	WP_037474518.1	GMC family oxidoreductase N-terminal domain-containing protein	-
YGS_RS21110	888789..889190	+	402	WP_004207001.1	DUF2147 domain-containing protein	-
YGS_RS21115	889344..889544	+	201	Protein_794	recombinase family protein	-
YGS_RS21120	889572..889880	+	309	WP_037474511.1	BrnT family toxin	Toxin
YGS_RS21125	889912..890196	+	285	WP_197421464.1	BrnA antitoxin family protein	Antitoxin
YGS_RS21130	890319..891079	+	761	WP_120252835.1	IS5 family transposase	-
YGS_RS21135	891100..891348	-	249	WP_120252836.1	hypothetical protein	-
YGS_RS26620	891358..891633	-	276	WP_145986290.1	hypothetical protein	-
YGS_RS21140	891745..892944	-	1200	Protein_800	MFS transporter	-
YGS_RS21145	893027..894394	-	1368	WP_120252837.1	Dyp-type peroxidase	-
YGS_RS21150	894398..895009	-	612	WP_017503242.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (8-93)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (1-82)

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 11845.32 Da
• Isoelectric Point: 6.6474

>T31844 WP_037474511.1 NZ_AP018519:889572-889880 [Sphingobium sp. YG1]
MPSMRFSWHPAKAESNLKKHGVSFAIATRAFTDPFALSDQDRIEGGERRWQTLGLVEGHLLLLVAHTVVEQDDDGEYVEI
IHIISARKADRTERRRYEEERR

Nucleotide

• Length: 309 bp

>T31844 NZ_AP018519:889572-889880 [Sphingobium sp. YG1]
ATGCCATCCATGCGCTTCTCCTGGCACCCGGCCAAAGCCGAGAGCAATCTGAAGAAGCACGGCGTCAGCTTTGCGATCGC
TACTCGTGCGTTCACAGATCCTTTCGCGCTGAGCGATCAGGATCGGATCGAAGGTGGCGAGCGACGATGGCAAACCTTGG
GCCTCGTGGAAGGGCATCTGCTCCTCCTCGTGGCCCACACTGTCGTCGAGCAAGACGATGACGGCGAGTATGTGGAGATC
ATTCATATCATTTCGGCTCGAAAGGCCGATCGAACGGAAAGGCGACGTTATGAAGAAGAAAGACGCTGA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10764.24 Da
• Isoelectric Point: 9.9870

>AT31844 WP_197421464.1 NZ_AP018519:889912-890196 [Sphingobium sp. YG1]
MPPLTEAQQAELDALQAMPDSGIDYSDSPALTEDFWRNGQRGRFYKPIKQQVTARLDADVLAWLKSQGKGYQARMNAILR
REMLATARRQEKPR

Nucleotide

• Length: 285 bp

>AT31844 NZ_AP018519:889912-890196 [Sphingobium sp. YG1]
CTGCCGCCGTTGACCGAAGCGCAACAGGCCGAACTGGATGCCCTGCAGGCGATGCCGGATAGCGGGATCGACTATAGCGA
CTCTCCGGCGCTGACAGAGGATTTCTGGCGGAACGGGCAGCGTGGGCGCTTCTATAAGCCCATCAAGCAGCAGGTGACGG
CACGCCTTGATGCTGATGTGCTCGCCTGGCTCAAATCGCAGGGTAAGGGCTACCAAGCCCGCATGAACGCCATACTTCGC
CGTGAGATGCTGGCGACCGCCAGAAGGCAGGAAAAGCCACGTTAA