Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 383395..383984 Replicon chromosome
Accession NZ_AP018519
Organism Sphingobium sp. YG1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag YGS_RS18665 Protein ID WP_120252556.1
Coordinates 383697..383984 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag YGS_RS18660 Protein ID WP_120252555.1
Coordinates 383395..383700 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YGS_RS18625 378576..379175 - 600 WP_145986272.1 GntR family transcriptional regulator -
YGS_RS18630 379486..379995 + 510 WP_120252550.1 helix-turn-helix domain-containing protein -
YGS_RS18635 380005..380499 - 495 WP_120252551.1 DUF2285 domain-containing protein -
YGS_RS18640 381249..382463 + 1215 WP_120252552.1 site-specific integrase -
YGS_RS18645 382438..382632 - 195 WP_096060525.1 helix-turn-helix domain-containing protein -
YGS_RS18650 382629..382844 - 216 WP_120252553.1 AlpA family phage regulatory protein -
YGS_RS18655 383144..383320 - 177 WP_120252554.1 hypothetical protein -
YGS_RS18660 383395..383700 + 306 WP_120252555.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
YGS_RS18665 383697..383984 + 288 WP_120252556.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
YGS_RS18670 384184..384786 + 603 WP_145986273.1 hypothetical protein -
YGS_RS18675 385067..385465 + 399 WP_120252558.1 hypothetical protein -
YGS_RS18680 385497..385889 + 393 WP_119750767.1 transposase -
YGS_RS18685 385943..386242 + 300 WP_120253468.1 IS66 family insertion sequence element accessory protein TnpB -
YGS_RS18690 386373..387149 + 777 WP_172598855.1 transposase -
YGS_RS18695 387206..388699 + 1494 WP_120253469.1 IS21 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-55)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10747.31 Da        Isoelectric Point: 8.6397

>T31843 WP_120252556.1 NZ_AP018519:383697-383984 [Sphingobium sp. YG1]
MKLAWSNRATTDRLAIFIWIAEDNPQAAADVDDRIEAAAQRLKDFPNSGRPGRIEGTRELVIARTPYIAPYQIIGDTVRV
LRVIHGARMWPHDIP

Download         Length: 288 bp

>T31843 NZ_AP018519:383697-383984 [Sphingobium sp. YG1]
ATGAAACTCGCTTGGTCCAATCGGGCGACGACTGATCGTCTGGCGATATTCATTTGGATTGCCGAGGATAATCCGCAAGC
CGCCGCCGATGTGGATGATCGGATCGAGGCAGCTGCCCAGCGCCTCAAAGATTTCCCGAATAGCGGGCGTCCGGGCCGGA
TCGAAGGCACGCGCGAATTGGTGATCGCGCGCACGCCCTATATCGCACCTTACCAGATCATCGGGGATACCGTGCGCGTC
CTTCGCGTGATCCATGGTGCGCGCATGTGGCCCCACGACATTCCCTAG

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11398.91 Da        Isoelectric Point: 4.9006

>AT31843 WP_120252555.1 NZ_AP018519:383395-383700 [Sphingobium sp. YG1]
MANNALIQTRIDSDVKDRAAAVFERMGLTVSDAVRILLTRTAREGVAPMELLVERQAYDQWFRARVQEALDDDRPDIDDA
EVSARFAELRANARKGIKPVQ

Download         Length: 306 bp

>AT31843 NZ_AP018519:383395-383700 [Sphingobium sp. YG1]
ATGGCCAACAATGCCCTTATCCAGACCCGAATCGATTCGGACGTGAAGGACCGCGCCGCCGCCGTGTTCGAGCGGATGGG
GCTTACGGTATCAGACGCCGTGCGCATCCTTTTGACCCGCACCGCGCGCGAGGGCGTTGCCCCCATGGAGCTGCTGGTAG
AGCGGCAAGCCTATGACCAGTGGTTCCGGGCGCGAGTGCAGGAGGCGCTGGACGATGATCGGCCCGATATTGACGACGCC
GAGGTTTCTGCGCGATTTGCTGAGCTTCGCGCGAACGCGCGAAAGGGTATCAAGCCGGTGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References