Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1907119..1907666 Replicon chromosome
Accession NZ_AP018518
Organism Sphingobium sp. YG1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag YGS_RS09295 Protein ID WP_120250686.1
Coordinates 1907382..1907666 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag YGS_RS09290 Protein ID WP_120250685.1
Coordinates 1907119..1907385 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YGS_RS09250 1902630..1902842 + 213 WP_120250679.1 ParD-like family protein -
YGS_RS09255 1902839..1903618 + 780 WP_120250680.1 type I methionyl aminopeptidase -
YGS_RS09265 1903789..1904268 - 480 WP_120250681.1 DUF1178 family protein -
YGS_RS09270 1904265..1905095 - 831 WP_120252143.1 carbon-nitrogen hydrolase family protein -
YGS_RS09275 1905101..1905358 - 258 WP_120250682.1 glutaredoxin 3 -
YGS_RS09280 1905416..1906162 - 747 WP_120250683.1 ComF family protein -
YGS_RS09285 1906204..1907055 + 852 WP_120250684.1 methyltransferase domain-containing protein -
YGS_RS09290 1907119..1907385 + 267 WP_120250685.1 ribbon-helix-helix domain-containing protein Antitoxin
YGS_RS09295 1907382..1907666 + 285 WP_120250686.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
YGS_RS09300 1907695..1908480 - 786 WP_120250687.1 DUF4019 domain-containing protein -
YGS_RS09305 1908706..1909602 - 897 WP_120250688.1 metallophosphoesterase -
YGS_RS09310 1909673..1910569 + 897 WP_120250689.1 YegS/Rv2252/BmrU family lipid kinase -
YGS_RS09315 1910669..1911217 - 549 WP_120250690.1 30S ribosomal protein S9 -
YGS_RS09320 1911217..1911696 - 480 WP_082462630.1 50S ribosomal protein L13 -
YGS_RS09325 1911831..1912613 - 783 WP_120250691.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10899.66 Da        Isoelectric Point: 9.9406

>T31842 WP_120250686.1 NZ_AP018518:1907382-1907666 [Sphingobium sp. YG1]
VKIVWTSKAASDLVRLHDHLKPVAPDAAARIVQMLAAAPSRLIDYPRIGERLDAYDQREVRRIIVGHYEMRYAVEGERIV
ILRLWHCREDRGRA

Download         Length: 285 bp

>T31842 NZ_AP018518:1907382-1907666 [Sphingobium sp. YG1]
GTGAAGATCGTCTGGACCAGCAAGGCCGCATCCGACCTTGTGCGTCTTCACGATCATTTGAAGCCCGTCGCGCCGGATGC
TGCCGCGCGCATCGTTCAGATGCTTGCGGCCGCGCCATCCCGCCTGATCGACTATCCCCGGATCGGCGAAAGACTGGACG
CCTATGATCAGCGCGAAGTCCGCCGCATCATCGTGGGACATTATGAAATGCGCTATGCCGTGGAGGGGGAGCGGATCGTG
ATCTTGCGGTTATGGCATTGCCGGGAAGATAGAGGGCGGGCCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9770.08 Da        Isoelectric Point: 4.3904

>AT31842 WP_120250685.1 NZ_AP018518:1907119-1907385 [Sphingobium sp. YG1]
MPATRVITAHVPTDLADQVDALADRLDRSRGWIMKQALSAWVDQEEMRHQMTLEALADVEAGQLIDHAAMLAWAQSLSTD
EPLTPPHL

Download         Length: 267 bp

>AT31842 NZ_AP018518:1907119-1907385 [Sphingobium sp. YG1]
ATGCCTGCCACCCGCGTCATCACCGCGCATGTCCCGACCGATCTGGCCGATCAGGTCGATGCCCTGGCCGATCGCCTCGA
TCGGTCGCGCGGATGGATCATGAAGCAGGCACTCTCCGCTTGGGTCGATCAGGAAGAAATGCGTCATCAGATGACGCTCG
AAGCCCTGGCCGATGTCGAGGCGGGACAGTTGATCGACCATGCAGCCATGCTCGCCTGGGCGCAAAGCCTCTCCACCGAC
GAACCGCTGACGCCCCCTCATCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References