Detailed information of TA system TA031841

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 1703309..1703819
• Replicon: chromosome
• Accession: NZ_AP018518
• Organism: Sphingobium sp. YG1

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: YGS_RS08260
• Protein ID: WP_120250527.1
• Coordinates: 1703571..1703819 (-)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: YGS_RS08255
• Protein ID: WP_120250526.1
• Coordinates: 1703309..1703578 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
YGS_RS08225	1699818..1700006	-	189	WP_120250522.1	hypothetical protein	-
YGS_RS08230	1700102..1700650	+	549	WP_120250523.1	shikimate kinase	-
YGS_RS08235	1700641..1701744	+	1104	WP_120250524.1	3-dehydroquinate synthase	-
YGS_RS08240	1701907..1702221	-	315	WP_172598825.1	hypothetical protein	-
YGS_RS08245	1702292..1702615	-	324	WP_120252109.1	YnfA family protein	-
YGS_RS08250	1702919..1703143	-	225	WP_120250525.1	50S ribosomal protein L31	-
YGS_RS08255	1703309..1703578	-	270	WP_120250526.1	BrnA antitoxin family protein	Antitoxin
YGS_RS08260	1703571..1703819	-	249	WP_120250527.1	BrnT family toxin	Toxin
YGS_RS08265	1703965..1704441	-	477	WP_120250528.1	3-hydroxyacyl-ACP dehydratase FabZ	-
YGS_RS08270	1704448..1705104	-	657	WP_120250529.1	OmpH family outer membrane protein	-
YGS_RS08275	1705104..1707800	-	2697	WP_172598769.1	outer membrane protein assembly factor BamA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-76)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (16-86)

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 9050.52 Da
• Isoelectric Point: 8.6831

>T31841 WP_120250527.1 NZ_AP018518:c1703819-1703571 [Sphingobium sp. YG1]
MIIIWDEPKRRANIVKHGIDFADIDESFFASAIIREAKQDRYAAIGRLNGVIAVIFAGLGSEGISIISARPASKMERMLF
NG

Nucleotide

• Length: 249 bp

>T31841 NZ_AP018518:c1703819-1703571 [Sphingobium sp. YG1]
ATGATCATCATATGGGATGAGCCGAAGCGACGGGCGAACATCGTCAAACATGGCATCGATTTTGCCGATATTGATGAGAG
TTTCTTCGCTTCTGCCATCATTCGTGAGGCCAAGCAGGATCGCTATGCTGCGATCGGGCGGCTGAATGGGGTCATAGCCG
TTATTTTCGCAGGATTGGGCAGCGAAGGGATTTCCATCATCTCCGCGCGTCCGGCCAGCAAGATGGAAAGGATGCTCTTC
AATGGGTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9740.94 Da
• Isoelectric Point: 8.6361

>AT31841 WP_120250526.1 NZ_AP018518:c1703578-1703309 [Sphingobium sp. YG1]
MGDQAYTQADADAVADNPEWTKEDFARAVPFNEAFPDLAATIRRRGAQKTPTKVSTTVRLDQDVLAKLKAGGPGWQTRLN
DVLRRALGV

Nucleotide

• Length: 270 bp

>AT31841 NZ_AP018518:c1703578-1703309 [Sphingobium sp. YG1]
ATGGGTGATCAGGCCTATACGCAAGCCGATGCCGATGCTGTCGCGGATAATCCGGAATGGACGAAAGAGGATTTTGCGCG
CGCGGTGCCTTTCAACGAGGCATTTCCGGACTTGGCGGCGACGATCCGCCGTCGCGGCGCGCAAAAGACACCGACGAAGG
TGAGTACGACGGTGCGTCTGGATCAGGACGTGCTGGCAAAGTTGAAAGCAGGCGGCCCCGGGTGGCAAACGCGGCTGAAT
GATGTTTTGCGCAGGGCGCTTGGCGTCTGA