Detailed information of TA system TA031840

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 1394149..1394789
• Replicon: chromosome
• Accession: NZ_AP018518
• Organism: Sphingobium sp. YG1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: YGS_RS06775
• Protein ID: WP_120250274.1
• Coordinates: 1394379..1394789 (+)
• Length: 137 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: YGS_RS06770
• Protein ID: WP_120250273.1
• Coordinates: 1394149..1394379 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
YGS_RS06760	1392518..1392970	-	453	WP_056689729.1	hypothetical protein	-
YGS_RS06765	1393099..1393770	+	672	WP_120252073.1	spermidine synthase	-
YGS_RS06770	1394149..1394379	+	231	WP_120250273.1	antitoxin	Antitoxin
YGS_RS06775	1394379..1394789	+	411	WP_120250274.1	tRNA(fMet)-specific endonuclease VapC	Toxin
YGS_RS06780	1395061..1398240	-	3180	WP_120250275.1	error-prone DNA polymerase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-124)

Antitoxin

• SpoVT-AbrB domain (7-50)

Sequences

Toxin

Protein

• Length: 137 a.a.
• Molecular weight: 15292.57 Da
• Isoelectric Point: 6.8541

>T31840 WP_120250274.1 NZ_AP018518:1394379-1394789 [Sphingobium sp. YG1]
MLKFMLDTNICIFTIKNRPQEVRAAFKRHHDQMCISSVTLMELIYGAEKSANPQRNLMDVEGFAARLEVLDYGREAAAHT
GQLRAELTRAGTPIGPYDQMIAGHARSCGMILVTNNLREFDRVPGLRVEDWVNEAG

Nucleotide

• Length: 411 bp

>T31840 NZ_AP018518:1394379-1394789 [Sphingobium sp. YG1]
ATGCTCAAATTCATGCTCGACACCAATATCTGCATCTTCACGATCAAGAACAGGCCGCAAGAGGTGCGCGCGGCATTCAA
ACGGCATCATGACCAGATGTGCATCAGTTCCGTCACCTTGATGGAGCTGATTTACGGCGCTGAAAAATCCGCCAATCCAC
AGCGCAATCTCATGGATGTGGAAGGCTTCGCCGCGCGGCTGGAGGTGCTTGACTACGGCCGGGAGGCTGCCGCCCATACA
GGGCAGTTGCGTGCAGAACTGACACGCGCAGGTACGCCGATCGGCCCCTATGACCAGATGATCGCTGGCCATGCCCGCTC
ATGCGGCATGATCCTCGTCACCAATAATCTGCGCGAATTCGACCGCGTGCCCGGCCTGCGCGTTGAGGATTGGGTCAATG
AAGCTGGGTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8452.43 Da
• Isoelectric Point: 4.6881

>AT31840 WP_120250273.1 NZ_AP018518:1394149-1394379 [Sphingobium sp. YG1]
VPQASIFQSNRSQAVRLPKAVALPDDVKRVDVIALGRTRIITPAGEAWDSWFDGAGVTADFMTDREQPDHQEREAF

Nucleotide

• Length: 231 bp

>AT31840 NZ_AP018518:1394149-1394379 [Sphingobium sp. YG1]
GTGCCACAAGCCTCTATATTTCAGAGCAACCGCAGCCAGGCGGTAAGATTGCCCAAGGCGGTCGCCCTGCCCGACGATGT
GAAGCGGGTCGATGTGATTGCTCTGGGCCGCACCCGGATCATCACCCCGGCAGGCGAAGCCTGGGATAGCTGGTTCGACG
GCGCAGGGGTGACCGCCGACTTCATGACAGATCGCGAGCAGCCGGATCATCAGGAGCGCGAAGCCTTCTGA