Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 255210..255759 Replicon chromosome
Accession NZ_AP018518
Organism Sphingobium sp. YG1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag YGS_RS01235 Protein ID WP_120249392.1
Coordinates 255457..255759 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag YGS_RS01230 Protein ID WP_120249391.1
Coordinates 255210..255455 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YGS_RS01205 250959..251744 + 786 WP_120251942.1 hypothetical protein -
YGS_RS01210 251741..252334 - 594 WP_120249387.1 TetR/AcrR family transcriptional regulator -
YGS_RS01215 252407..253120 + 714 WP_120249388.1 SDR family oxidoreductase -
YGS_RS01220 253145..253531 - 387 WP_120249389.1 hypothetical protein -
YGS_RS01225 253703..255076 - 1374 WP_120249390.1 amidohydrolase -
YGS_RS01230 255210..255455 + 246 WP_120249391.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
YGS_RS01235 255457..255759 + 303 WP_120249392.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
YGS_RS01240 255766..257286 - 1521 WP_120249393.1 peptidase S10 -
YGS_RS01245 257909..258700 - 792 WP_120249394.1 3-hydroxybutyrate dehydrogenase -
YGS_RS01250 258697..259890 - 1194 WP_120249395.1 DUF3734 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11638.15 Da        Isoelectric Point: 6.3250

>T31839 WP_120249392.1 NZ_AP018518:255457-255759 [Sphingobium sp. YG1]
MARYRLSQAASDDISHIFLDGLTRFGLAQADRYHAGMAAVFDFLADYPQAARLREEIRPPVRAHPYRSHLILYDIMDDGW
ILVLRVRHGREDWQDENPSI

Download         Length: 303 bp

>T31839 NZ_AP018518:255457-255759 [Sphingobium sp. YG1]
ATGGCGCGTTATCGACTGAGCCAGGCGGCGTCGGACGATATCAGCCACATTTTTTTGGACGGCCTGACCCGCTTCGGCTT
GGCCCAGGCGGATCGCTATCATGCGGGCATGGCGGCAGTCTTCGATTTTCTGGCCGATTATCCGCAGGCCGCACGGTTGC
GGGAGGAGATCAGGCCGCCGGTTCGTGCCCATCCCTATCGCTCCCATTTGATCCTGTACGATATCATGGACGATGGTTGG
ATACTTGTCCTGCGCGTCCGCCACGGGCGGGAGGACTGGCAGGACGAGAATCCCTCCATCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9156.37 Da        Isoelectric Point: 7.0110

>AT31839 WP_120249391.1 NZ_AP018518:255210-255455 [Sphingobium sp. YG1]
MATMNISLPDPMKIWVEGQADTGRYSNASDYVRDLIRRDQERQAKIAHMQRLVDDARSSGMAEESMADMRVRLAKQAGVQ
S

Download         Length: 246 bp

>AT31839 NZ_AP018518:255210-255455 [Sphingobium sp. YG1]
ATGGCGACCATGAATATTTCCCTTCCCGATCCGATGAAAATTTGGGTCGAGGGCCAAGCCGACACTGGGCGTTATAGCAA
TGCCAGCGATTATGTTCGCGACCTGATCCGGCGCGATCAGGAGCGGCAGGCGAAGATCGCTCATATGCAGCGGTTGGTCG
ATGACGCGCGGTCGAGCGGCATGGCTGAGGAAAGCATGGCGGATATGCGCGTAAGGCTGGCAAAGCAGGCGGGCGTGCAA
AGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References