Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 60311..60840 Replicon plasmid pAOF1
Accession NZ_AP018516
Organism Acetobacter orientalis strain FAN1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AcetOrient_RS14045 Protein ID WP_086658415.1
Coordinates 60550..60840 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AcetOrient_RS14040 Protein ID WP_048839603.1
Coordinates 60311..60553 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AcetOrient_RS14025 55616..57649 + 2034 WP_126621607.1 hypothetical protein -
AcetOrient_RS14030 58566..58979 - 414 WP_126621608.1 hypothetical protein -
AcetOrient_RS14035 58994..59548 - 555 WP_126621609.1 SocA family protein -
AcetOrient_RS14040 60311..60553 + 243 WP_048839603.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AcetOrient_RS14045 60550..60840 + 291 WP_086658415.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AcetOrient_RS14050 60843..61925 + 1083 WP_086658416.1 hypothetical protein -
AcetOrient_RS14055 62273..62845 + 573 Protein_58 IS701 family transposase -
AcetOrient_RS14060 62901..63658 + 758 WP_126621610.1 IS5 family transposase -
AcetOrient_RS14065 63912..64550 + 639 WP_126621611.1 tyrosine-type recombinase/integrase -
AcetOrient_RS14070 64558..64896 + 339 WP_197719581.1 prevent-host-death protein -
AcetOrient_RS14075 64893..65276 + 384 WP_126621612.1 type II toxin-antitoxin system VapC family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..173853 173853


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-78)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11066.95 Da        Isoelectric Point: 10.8866

>T31838 WP_086658415.1 NZ_AP018516:60550-60840 [Acetobacter orientalis]
VSRYTLQFDPRALKEWRSLDRTIQAQFKKVLAKRLEAPRIEASRLSGPLSDCYKIKLRASGYRLVYRVIDSDIIVLVLAI
GERDKSRAYAQAGKRL

Download         Length: 291 bp

>T31838 NZ_AP018516:60550-60840 [Acetobacter orientalis]
GTGAGCCGCTACACACTCCAGTTTGATCCCCGCGCCCTGAAGGAATGGCGCAGTCTTGACCGCACGATTCAGGCGCAATT
CAAGAAAGTTCTGGCCAAACGGCTGGAAGCGCCCCGGATCGAAGCCTCCCGCCTGTCAGGGCCACTGAGCGATTGCTACA
AAATCAAGCTCCGGGCCAGTGGCTACAGGCTGGTCTATCGGGTGATCGACAGCGACATCATCGTGCTGGTTCTGGCAATC
GGGGAACGTGATAAGTCCAGAGCCTATGCACAGGCTGGCAAACGGCTCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8849.11 Da        Isoelectric Point: 4.4865

>AT31838 WP_048839603.1 NZ_AP018516:60311-60553 [Acetobacter orientalis]
MASINLRIDSLLKDQAYARLAELGVTPSDLIRQTFEYVVETGKLPVSRHVLSTEDADLLQVARERLATPQAPVTVTLDDL

Download         Length: 243 bp

>AT31838 NZ_AP018516:60311-60553 [Acetobacter orientalis]
ATGGCGTCCATCAATCTGAGGATCGATAGCCTCCTGAAGGATCAGGCCTATGCCCGTCTCGCGGAACTGGGCGTGACGCC
GTCCGACCTGATCCGCCAGACCTTCGAATATGTCGTAGAGACTGGAAAACTGCCGGTGTCTCGCCATGTCCTCTCCACAG
AGGATGCGGATCTGCTGCAGGTTGCACGCGAACGCCTCGCGACACCGCAAGCGCCCGTAACGGTGACACTGGATGACCTG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References