Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/MazF(toxin)
Location 10412573..10413147 Replicon chromosome
Accession NZ_AP018255
Organism Calothrix sp. NIES-4071

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag CDC41_RS46010 Protein ID WP_096692917.1
Coordinates 10412803..10413147 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag CDC41_RS46005 Protein ID WP_096694535.1
Coordinates 10412573..10412809 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC41_RS46000 10412004..10412426 + 423 WP_096692916.1 transcriptional regulator -
CDC41_RS46005 10412573..10412809 + 237 WP_096694535.1 ribbon-helix-helix domain-containing protein Antitoxin
CDC41_RS46010 10412803..10413147 + 345 WP_096692917.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CDC41_RS46015 10413271..10413675 - 405 WP_096692918.1 transcriptional regulator -
CDC41_RS46020 10413659..10413958 - 300 WP_096692919.1 type II toxin-antitoxin system HigB family toxin -
CDC41_RS46025 10414109..10414507 - 399 WP_096692920.1 hypothetical protein -
CDC41_RS46030 10414635..10415888 + 1254 WP_096692921.1 lipid-A-disaccharide synthase -
CDC41_RS46035 10415950..10416333 - 384 WP_096692922.1 hypothetical protein -
CDC41_RS46040 10416617..10417309 + 693 WP_096692923.1 M23 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-114)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12754.83 Da        Isoelectric Point: 4.5881

>T31739 WP_096692917.1 NZ_AP018255:10412803-10413147 [Calothrix sp. NIES-4071]
MVMLRGEIWWANLPKPIASEPGYRRPVLIIQSNDFNQSRIRTVIVAILTTNLRLGDAPGNILLTTEETDLPQDSVVNVSQ
VITVDKTFLEEKVSQLSDRAMLLVEDGLRLVLAL

Download         Length: 345 bp

>T31739 NZ_AP018255:10412803-10413147 [Calothrix sp. NIES-4071]
TTGGTAATGTTGCGAGGTGAAATTTGGTGGGCAAACCTTCCGAAACCTATTGCCTCTGAACCAGGATATCGTAGACCAGT
TCTGATAATACAGTCGAATGATTTTAACCAAAGCAGAATCCGGACTGTTATTGTTGCAATACTAACAACTAATCTACGTT
TAGGTGATGCTCCTGGTAATATATTATTAACAACTGAAGAGACAGATTTACCACAAGATTCTGTCGTTAATGTTTCGCAA
GTTATTACTGTGGACAAAACATTTCTGGAAGAAAAGGTTAGTCAATTAAGCGACCGTGCAATGCTGCTTGTTGAAGATGG
TCTTCGTTTAGTTCTTGCCTTGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9112.14 Da        Isoelectric Point: 4.0700

>AT31739 WP_096694535.1 NZ_AP018255:10412573-10412809 [Calothrix sp. NIES-4071]
MKTAISIPDPLFEAAEQFAKRMGLSRSELYAVALQQYLQNHKYDQITNQLNEVYAEEDSSIDPYFVQMQAYTLSEENW

Download         Length: 237 bp

>AT31739 NZ_AP018255:10412573-10412809 [Calothrix sp. NIES-4071]
ATGAAAACAGCCATATCAATCCCCGACCCGCTTTTTGAAGCTGCTGAACAATTTGCAAAACGGATGGGATTATCTCGCAG
CGAACTATATGCTGTAGCGCTTCAGCAGTATCTACAAAATCATAAATACGACCAAATCACAAACCAATTGAACGAAGTAT
ATGCAGAAGAAGACAGCAGTATTGACCCTTACTTCGTTCAAATGCAAGCTTATACATTGTCTGAGGAAAATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References