Detailed information of TA system TA031738

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 9862784..9863258
• Replicon: chromosome
• Accession: NZ_AP018255
• Organism: Calothrix sp. NIES-4071

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CDC41_RS43460
• Protein ID: WP_096692470.1
• Coordinates: 9862784..9863044 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CDC41_RS43465
• Protein ID: WP_096692471.1
• Coordinates: 9863034..9863258 (+)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDC41_RS43445	9858658..9859278	+	621	WP_096692467.1	dihydroxyacetone kinase subunit L	-
CDC41_RS43450	9859370..9861916	+	2547	WP_096692468.1	phosphoenolpyruvate--protein phosphotransferase	-
CDC41_RS43455	9862144..9862515	+	372	WP_096729170.1	hypothetical protein	-
CDC41_RS43460	9862784..9863044	+	261	WP_096692470.1	BrnT family toxin	Toxin
CDC41_RS43465	9863034..9863258	+	225	WP_096692471.1	CopG family transcriptional regulator	Antitoxin
CDC41_RS43470	9863374..9863592	-	219	WP_096692472.1	hypothetical protein	-
CDC41_RS43475	9863829..9864674	-	846	WP_096692473.1	tetratricopeptide repeat protein	-
CDC41_RS43480	9865181..9866092	-	912	WP_096692474.1	ribonuclease D	-
CDC41_RS43485	9866193..9867900	+	1708	Protein_8624	phosphoglycolate phosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10305.63 Da
• Isoelectric Point: 5.9006

>T31738 WP_096692470.1 NZ_AP018255:9862784-9863044 [Calothrix sp. NIES-4071]
MRFEFDERKSASNKVKHGIDFVEAQELWFDTNRVEVAARNVDEPRFLVIGQINAKYWAAVITYREERVRIISVRRARDEE
IQIYES

Nucleotide

• Length: 261 bp

>T31738 NZ_AP018255:9862784-9863044 [Calothrix sp. NIES-4071]
ATGCGATTCGAGTTTGACGAGCGAAAAAGTGCTTCAAATAAAGTCAAACATGGTATTGATTTTGTTGAGGCGCAAGAACT
ATGGTTTGATACAAATCGAGTAGAAGTTGCTGCTCGTAATGTTGATGAGCCAAGGTTCCTTGTGATAGGACAAATAAATG
CAAAGTACTGGGCTGCTGTGATCACGTATAGAGAGGAGCGGGTGCGAATTATATCAGTAAGGCGAGCAAGAGATGAGGAG
ATACAAATATATGAAAGCTGA

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8737.83 Da
• Isoelectric Point: 4.6412

>AT31738 WP_096692471.1 NZ_AP018255:9863034-9863258 [Calothrix sp. NIES-4071]
MKAEEFDEKFDSGEDITPYLDMNTIRRPGYEQRRVNVDFPAWVIEALDREAARIGVTRQSIIKVWIAERLEQHS

Nucleotide

• Length: 225 bp

>AT31738 NZ_AP018255:9863034-9863258 [Calothrix sp. NIES-4071]
ATGAAAGCTGAAGAATTTGATGAAAAATTTGATTCTGGTGAGGATATAACTCCTTATTTAGACATGAACACAATTCGTCG
TCCTGGTTATGAGCAACGACGGGTAAATGTTGATTTTCCTGCATGGGTTATTGAGGCACTTGACCGGGAAGCCGCGCGAA
TTGGTGTAACTCGACAATCAATAATAAAAGTATGGATTGCCGAGCGGCTGGAACAGCATAGCTAA