Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 8511046..8511559 Replicon chromosome
Accession NZ_AP018255
Organism Calothrix sp. NIES-4071

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag CDC41_RS37400 Protein ID WP_096691443.1
Coordinates 8511293..8511559 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CDC41_RS37395 Protein ID WP_096694426.1
Coordinates 8511046..8511300 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC41_RS37385 8507179..8507859 + 681 WP_096691442.1 PEP-CTERM sorting domain-containing protein -
CDC41_RS37390 8507926..8509797 - 1872 WP_096694425.1 peroxidase -
CDC41_RS37395 8511046..8511300 + 255 WP_096694426.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CDC41_RS37400 8511293..8511559 + 267 WP_096691443.1 Txe/YoeB family addiction module toxin Toxin
CDC41_RS37405 8511794..8513398 + 1605 WP_096691444.1 Hsp70 family protein -
CDC41_RS37410 8513559..8513930 + 372 WP_096691445.1 hypothetical protein -
CDC41_RS37415 8514030..8514605 - 576 WP_096691446.1 hypothetical protein -
CDC41_RS37420 8515154..8515531 + 378 Protein_7417 hypothetical protein -
CDC41_RS37425 8515527..8516072 + 546 WP_096691447.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10459.99 Da        Isoelectric Point: 6.9759

>T31735 WP_096691443.1 NZ_AP018255:8511293-8511559 [Calothrix sp. NIES-4071]
MSRKLAWTDAAWLDYLYWQGQDKKTLKRINKLIEATMRLPFEGIGKPEALLENLAGFWSRRIDDTNRLVYAVDDEYLTII
ACRYHYSE

Download         Length: 267 bp

>T31735 NZ_AP018255:8511293-8511559 [Calothrix sp. NIES-4071]
ATGAGTAGAAAGTTAGCGTGGACAGATGCGGCTTGGCTTGATTATTTATATTGGCAAGGACAGGACAAGAAAACTTTAAA
ACGAATTAACAAGTTGATTGAGGCAACCATGCGACTACCGTTTGAGGGAATAGGGAAACCAGAAGCACTACTCGAGAATC
TGGCAGGTTTTTGGTCGCGGCGAATTGATGATACGAATCGGTTAGTTTATGCAGTGGATGATGAGTATTTAACGATTATT
GCTTGTCGATACCACTATTCTGAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9426.73 Da        Isoelectric Point: 5.0878

>AT31735 WP_096694426.1 NZ_AP018255:8511046-8511300 [Calothrix sp. NIES-4071]
MKVVSFSEARNNLKDVLDRVVEDADYTIITRRDAADAVVMSLDVFNSLLETVHLLKSPANAAHLERSVAQFKQGKVVERN
LLDE

Download         Length: 255 bp

>AT31735 NZ_AP018255:8511046-8511300 [Calothrix sp. NIES-4071]
ATGAAAGTTGTGTCTTTTAGCGAAGCGAGAAATAACCTCAAAGATGTTTTAGACCGAGTGGTGGAAGATGCCGACTATAC
GATCATTACTAGAAGAGATGCAGCGGATGCTGTGGTGATGTCTCTAGATGTATTTAATAGTTTGTTAGAGACGGTACATT
TACTTAAATCTCCCGCTAATGCTGCCCATTTAGAGCGTTCTGTTGCTCAGTTCAAGCAGGGGAAAGTAGTGGAGCGAAAT
TTGTTGGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References