Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 6817403..6818190 Replicon chromosome
Accession NZ_AP018255
Organism Calothrix sp. NIES-4071

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag CDC41_RS29740 Protein ID WP_096690153.1
Coordinates 6817696..6818190 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag CDC41_RS29735 Protein ID WP_096690152.1
Coordinates 6817403..6817681 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC41_RS29720 6813486..6814568 - 1083 WP_096690149.1 photosystem II q(b) protein -
CDC41_RS29725 6814898..6815875 - 978 WP_096690150.1 HNH endonuclease -
CDC41_RS29730 6815981..6817264 - 1284 WP_096690151.1 AAA-like domain-containing protein -
CDC41_RS29735 6817403..6817681 + 279 WP_096690152.1 DUF1778 domain-containing protein Antitoxin
CDC41_RS29740 6817696..6818190 + 495 WP_096690153.1 GNAT family N-acetyltransferase Toxin
CDC41_RS29745 6818238..6818459 + 222 WP_096690154.1 DUF2281 domain-containing protein -
CDC41_RS29750 6818459..6818863 + 405 WP_096690155.1 type II toxin-antitoxin system VapC family toxin -
CDC41_RS29755 6818966..6822691 + 3726 WP_096690156.1 AAA-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(39-142)

Antitoxin

Vibrio phage ICP1, Orf50

(3-91)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18199.97 Da        Isoelectric Point: 7.9175

>T31731 WP_096690153.1 NZ_AP018255:6817696-6818190 [Calothrix sp. NIES-4071]
VLRIEKLSNTHNIDDFDCGSADLNRFLQRYALQSIQSNSAQTYVACLDEGVIGFYSLAVGSVMHDEAPTRVTKGLAKHPI
PVMILARLAVSTREQGKGIGKGLLKDALKRTYQAADIAGIRALLVHAKDDEARAWYEKFDFEASPTDPLHLFLLMKDIKK
ILQS

Download         Length: 495 bp

>T31731 NZ_AP018255:6817696-6818190 [Calothrix sp. NIES-4071]
GTGCTTAGAATAGAAAAATTATCAAATACTCATAATATCGATGATTTTGACTGTGGAAGTGCAGATTTAAACCGCTTTTT
ACAGCGTTATGCTTTGCAAAGCATACAGTCAAATAGTGCCCAAACCTATGTAGCTTGTTTAGATGAAGGTGTAATAGGTT
TTTACAGTTTAGCTGTTGGCTCTGTTATGCATGATGAGGCGCCGACTCGTGTAACTAAAGGGCTAGCAAAACATCCTATA
CCAGTAATGATTTTGGCTCGTTTGGCAGTATCCACCAGAGAACAAGGAAAAGGAATAGGTAAAGGATTGTTGAAAGATGC
ATTAAAGCGTACATATCAAGCTGCTGATATTGCAGGAATAAGGGCATTACTTGTTCACGCCAAAGATGATGAAGCGCGCG
CGTGGTATGAAAAGTTTGATTTTGAAGCAAGTCCAACCGACCCATTACATCTTTTTTTATTAATGAAGGACATCAAGAAA
ATATTACAATCTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10434.73 Da        Isoelectric Point: 5.1374

>AT31731 WP_096690152.1 NZ_AP018255:6817403-6817681 [Calothrix sp. NIES-4071]
MQSQSESKSERIDIRTSPAVKNLLQQAASASHKNVSEFLLEHGLIAASEALTNRVLFVLDDEKWQAFQEALDRPTQEKPN
LRRLLTEPSVFE

Download         Length: 279 bp

>AT31731 NZ_AP018255:6817403-6817681 [Calothrix sp. NIES-4071]
ATGCAAAGTCAATCAGAATCCAAGTCCGAAAGAATCGACATTCGTACAAGTCCTGCAGTCAAGAACTTGTTGCAGCAGGC
AGCATCAGCATCCCACAAAAATGTCAGCGAGTTTTTGCTAGAACATGGCTTAATAGCCGCATCAGAAGCATTGACAAATC
GCGTTTTATTTGTGTTAGACGATGAAAAATGGCAAGCTTTTCAAGAAGCGTTAGACCGTCCCACACAAGAAAAGCCCAAT
CTAAGACGCCTTTTGACAGAACCAAGTGTGTTTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References