Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 5040975..5041534 Replicon chromosome
Accession NZ_AP018255
Organism Calothrix sp. NIES-4071

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CDC41_RS21645 Protein ID WP_096688772.1
Coordinates 5040975..5041313 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CDC41_RS21650 Protein ID WP_096688773.1
Coordinates 5041310..5041534 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC41_RS21635 5036911..5037936 - 1026 WP_096688770.1 type I glyceraldehyde-3-phosphate dehydrogenase -
CDC41_RS21640 5038163..5040580 - 2418 WP_096688771.1 phosphoketolase family protein -
CDC41_RS21645 5040975..5041313 - 339 WP_096688772.1 DUF5615 family PIN-like protein Toxin
CDC41_RS21650 5041310..5041534 - 225 WP_096688773.1 DUF433 domain-containing protein Antitoxin
CDC41_RS21655 5041624..5042259 + 636 Protein_4302 type I restriction endonuclease subunit R -
CDC41_RS21660 5042477..5043106 - 630 WP_096688774.1 ribosome maturation factor RimM -
CDC41_RS21665 5043201..5044502 - 1302 WP_096688775.1 valine--pyruvate transaminase -
CDC41_RS21670 5044605..5045714 + 1110 WP_096688776.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
CDC41_RS21675 5045858..5046328 + 471 WP_096688777.1 DUF4174 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12296.16 Da        Isoelectric Point: 4.0920

>T31730 WP_096688772.1 NZ_AP018255:c5041313-5040975 [Calothrix sp. NIES-4071]
MNIWIDAQLPPTLAGWLSSTFNVNAQSLKDLGLRDALDTVIFEAAQIPGNVIMTKDSDFVDLVCRLGTPPQILWLTCGNV
TNRNLQQLLTATFPTALEQLRQGEAIVEISTL

Download         Length: 339 bp

>T31730 NZ_AP018255:c5041313-5040975 [Calothrix sp. NIES-4071]
ATGAATATTTGGATTGATGCTCAATTGCCACCAACACTGGCAGGTTGGTTAAGTAGCACGTTCAATGTGAATGCTCAATC
ATTAAAAGACTTAGGATTGCGTGACGCTTTAGATACTGTCATTTTTGAGGCGGCTCAAATCCCTGGAAATGTAATTATGA
CAAAAGATAGCGATTTTGTTGATTTGGTCTGTCGTTTGGGTACACCACCCCAAATTCTCTGGTTAACATGTGGGAATGTA
ACTAATCGTAATTTACAGCAACTGTTAACAGCTACTTTTCCTACAGCGTTAGAACAATTAAGACAAGGTGAGGCAATTGT
GGAAATAAGTACATTGTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8321.63 Da        Isoelectric Point: 4.4815

>AT31730 WP_096688773.1 NZ_AP018255:c5041534-5041310 [Calothrix sp. NIES-4071]
MNNLLSRITQTPGQCGGRPCIRGMRIRVSDILEMLSENVSTTEILEDFPDLEPEDIQACLLFAAKRTEFPRLVA

Download         Length: 225 bp

>AT31730 NZ_AP018255:c5041534-5041310 [Calothrix sp. NIES-4071]
ATGAATAACTTGCTATCCCGTATTACACAAACTCCTGGTCAATGTGGTGGGCGCCCCTGCATTAGAGGAATGAGAATTAG
AGTCAGCGATATTTTGGAAATGTTATCTGAGAACGTAAGTACTACAGAGATTTTAGAAGACTTTCCTGACCTTGAGCCAG
AGGATATTCAAGCTTGTCTTCTGTTTGCAGCTAAACGTACTGAGTTTCCGAGATTAGTTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References