Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 3764287..3765192 Replicon chromosome
Accession NZ_AP018255
Organism Calothrix sp. NIES-4071

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag CDC41_RS16000 Protein ID WP_096687804.1
Coordinates 3764749..3765192 (+) Length 148 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag CDC41_RS15995 Protein ID WP_096687803.1
Coordinates 3764287..3764739 (+) Length 151 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC41_RS15990 3760085..3760357 + 273 WP_096694147.1 CRISPR-associated endonuclease Cas2 -
CDC41_RS15995 3764287..3764739 + 453 WP_096687803.1 nucleotidyltransferase domain-containing protein Antitoxin
CDC41_RS16000 3764749..3765192 + 444 WP_096687804.1 DUF86 domain-containing protein Toxin
CDC41_RS16005 3765399..3768524 - 3126 WP_096687805.1 CHAT domain-containing protein -
CDC41_RS16010 3768940..3769317 + 378 WP_096687806.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-131)

Antitoxin

Polymerase beta, nucleotidyltransferase

(23-113)


Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 16868.37 Da        Isoelectric Point: 4.6251

>T31729 WP_096687804.1 NZ_AP018255:3764749-3765192 [Calothrix sp. NIES-4071]
MKREPVTSRLVLIIKYLNRLREFESVSVDEYLNSFDYQLIAERLIQLLVDVASDINTYILVQLHNIVPSAYYDSFVEAGK
KGIVTRELALGLAASAGMRNRLVHQYEVIDNRIVFSAIPIALDQYQLYVQEITSFLDSLEITEHDSI

Download         Length: 444 bp

>T31729 NZ_AP018255:3764749-3765192 [Calothrix sp. NIES-4071]
ATGAAACGAGAACCTGTTACAAGTAGACTTGTGTTAATAATCAAGTATCTAAATAGGTTGCGTGAGTTTGAATCGGTGAG
TGTTGATGAGTATTTAAATAGTTTTGACTATCAACTGATTGCTGAAAGGTTAATCCAGTTATTAGTTGATGTTGCTTCAG
ATATTAATACTTATATATTGGTGCAATTACATAATATTGTTCCATCAGCTTACTATGATTCTTTTGTTGAGGCTGGAAAA
AAGGGTATTGTTACAAGAGAACTAGCTTTAGGGCTTGCGGCTTCAGCAGGAATGCGAAATCGCTTGGTTCATCAGTATGA
GGTGATTGACAATCGTATCGTTTTTTCGGCTATCCCTATAGCTTTAGATCAATATCAGTTATATGTACAGGAAATTACAA
GTTTCTTAGATTCTTTGGAAATAACAGAGCATGACTCAATCTAA

Antitoxin


Download         Length: 151 a.a.        Molecular weight: 17472.22 Da        Isoelectric Point: 7.2148

>AT31729 WP_096687803.1 NZ_AP018255:3764287-3764739 [Calothrix sp. NIES-4071]
MVNKTPTVAELRELSLRLPENIPYVKMLVLFGSRARGDIHANSDWDFAVICDENQRLDYVKDNPFLWFELPAKVGEILQI
NSDIIDVVELDHCSPLMGYHVARDAKVLYESKPESFLRFQCKAWKIYADTAKFRKAERESIKLWLNKRGL

Download         Length: 453 bp

>AT31729 NZ_AP018255:3764287-3764739 [Calothrix sp. NIES-4071]
ATGGTAAATAAAACACCAACAGTTGCAGAATTGAGAGAACTTTCTTTGCGACTTCCAGAGAACATTCCGTATGTTAAAAT
GCTAGTTTTATTCGGTTCGAGAGCTAGAGGTGATATTCATGCTAATAGTGATTGGGATTTTGCTGTAATTTGTGATGAGA
ACCAACGTTTAGATTATGTAAAGGATAATCCTTTTTTGTGGTTTGAGCTACCTGCAAAAGTTGGCGAGATTCTCCAAATC
AATAGCGATATTATAGATGTGGTAGAACTTGATCATTGTTCGCCATTGATGGGTTATCATGTAGCCCGTGATGCTAAGGT
TTTATATGAAAGTAAACCAGAGAGTTTTCTTAGATTTCAATGCAAAGCCTGGAAGATTTATGCTGATACAGCAAAATTCC
GCAAAGCTGAAAGAGAATCTATAAAACTCTGGTTGAATAAAAGAGGGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References