Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 3499194..3500023 Replicon chromosome
Accession NZ_AP018255
Organism Calothrix sp. NIES-4071

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CDC41_RS14745 Protein ID WP_096694132.1
Coordinates 3499194..3499655 (-) Length 154 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag CDC41_RS14750 Protein ID WP_096687584.1
Coordinates 3499715..3500023 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC41_RS14725 3495182..3497329 - 2148 WP_096687582.1 glycine--tRNA ligase subunit beta -
CDC41_RS14730 3497582..3497945 - 364 Protein_2924 hypothetical protein -
CDC41_RS14735 3497942..3498115 - 174 WP_096694131.1 DUF433 domain-containing protein -
CDC41_RS14740 3498395..3499006 + 612 WP_096687583.1 hypothetical protein -
CDC41_RS14745 3499194..3499655 - 462 WP_096694132.1 GNAT family N-acetyltransferase Toxin
CDC41_RS14750 3499715..3500023 - 309 WP_096687584.1 DUF1778 domain-containing protein Antitoxin
CDC41_RS14755 3500610..3501068 + 459 WP_096687585.1 hypothetical protein -
CDC41_RS14760 3501335..3501520 - 186 WP_096687586.1 hypothetical protein -
CDC41_RS14765 3501933..3503015 - 1083 WP_096687587.1 ParB/RepB/Spo0J family partition protein -
CDC41_RS14770 3503012..3503704 - 693 Protein_2932 chromosome partitioning protein ParA -
CDC41_RS14775 3504596..3505015 + 420 WP_096687588.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(34-128)

Antitoxin

Vibrio phage ICP1, Orf50

(9-98)


Sequences

Toxin        


Download         Length: 154 a.a.        Molecular weight: 16700.39 Da        Isoelectric Point: 8.4693

>T31728 WP_096694132.1 NZ_AP018255:c3499655-3499194 [Calothrix sp. NIES-4071]
MDFDSGNAELDEWLRKRALKNEASGASRTYVVTVAEEVIAYYCLANGSVVNTTAPGKVRRNMPDPIPVMVIGRLAVDRRW
QGQGIGYALMRDAVLRTLQASEIAGIRAILVHAISLDAKQFYQKCGFIPSPVAPMTLMVTLNDAKEALGMTSI

Download         Length: 462 bp

>T31728 NZ_AP018255:c3499655-3499194 [Calothrix sp. NIES-4071]
ATGGATTTTGATTCCGGCAATGCCGAATTGGATGAGTGGTTAAGAAAGCGTGCCCTGAAAAACGAAGCCAGTGGTGCGTC
CAGAACCTATGTGGTCACGGTTGCAGAAGAAGTCATCGCTTATTATTGTCTGGCGAACGGCAGTGTCGTTAATACGACTG
CTCCCGGTAAAGTCCGACGCAATATGCCTGACCCGATTCCCGTTATGGTGATCGGGCGACTGGCAGTGGACAGACGCTGG
CAAGGACAAGGAATAGGTTATGCTCTCATGCGGGATGCGGTACTTCGGACTCTCCAGGCTTCTGAGATTGCGGGTATCAG
GGCGATCCTCGTTCATGCCATTTCTCTCGACGCGAAGCAATTTTATCAAAAATGCGGTTTTATACCCTCACCTGTTGCCC
CGATGACGCTCATGGTCACGCTCAACGATGCTAAAGAAGCGCTTGGCATGACATCGATTTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11706.31 Da        Isoelectric Point: 6.7192

>AT31728 WP_096687584.1 NZ_AP018255:c3500023-3499715 [Calothrix sp. NIES-4071]
MQPHTGMSNHQNRDVTINIRAHQRQRDLIDRAAESLGKNRSDFMLEVACREAEAVLLDRRLFMLDDEKFQEFMTLLDAPP
SVNANLRTLLTTKAPWEQGAKA

Download         Length: 309 bp

>AT31728 NZ_AP018255:c3500023-3499715 [Calothrix sp. NIES-4071]
ATGCAGCCACATACCGGAATGTCCAATCATCAAAACCGTGATGTCACGATCAACATCAGGGCACATCAGAGACAGCGAGA
TTTGATCGACCGGGCAGCGGAATCCCTTGGCAAGAACCGTTCCGATTTCATGCTGGAGGTAGCGTGTCGGGAAGCAGAAG
CGGTTTTGCTGGATCGTCGGCTTTTTATGCTGGATGATGAAAAATTTCAGGAATTTATGACGTTGCTGGATGCACCGCCT
TCTGTGAACGCAAACCTCCGGACGCTGCTGACTACCAAAGCTCCGTGGGAACAGGGGGCTAAGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References