Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 5753707..5754335 Replicon chromosome
Accession NZ_AP018254
Organism Calothrix sp. NIES-3974

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CDC37_RS22865 Protein ID WP_096625434.1
Coordinates 5753707..5754108 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CDC37_RS22870 Protein ID WP_096626566.1
Coordinates 5754108..5754335 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC37_RS22855 5750167..5752011 - 1845 WP_096625430.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
CDC37_RS22860 5752396..5753607 + 1212 WP_096625432.1 FAD-binding oxidoreductase -
CDC37_RS22865 5753707..5754108 - 402 WP_096625434.1 type II toxin-antitoxin system VapC family toxin Toxin
CDC37_RS22870 5754108..5754335 - 228 WP_096626566.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CDC37_RS24800 5754426..5754611 - 186 WP_172892817.1 hypothetical protein -
CDC37_RS24610 5754663..5754839 - 177 WP_157780825.1 hypothetical protein -
CDC37_RS22875 5755037..5756071 - 1035 WP_096625436.1 cyanophycinase -
CDC37_RS22880 5756509..5756739 - 231 WP_197707089.1 hypothetical protein -
CDC37_RS22885 5757370..5757765 + 396 WP_096625440.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-118)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14983.33 Da        Isoelectric Point: 4.4944

>T31724 WP_096625434.1 NZ_AP018254:c5754108-5753707 [Calothrix sp. NIES-3974]
MQFLLDTNTCIYIIKNKPPEVLAKFQTLDISDVGISSITVAELEYGVYKSQRQEQNRAALSQFLIPLEILPFDTQSTQTY
GRLRAELERQGIAIGSMDMLIASQAIALGLILVTNNLRELSRIPELVLENWVN

Download         Length: 402 bp

>T31724 NZ_AP018254:c5754108-5753707 [Calothrix sp. NIES-3974]
ATGCAATTCCTGCTCGATACTAATACATGCATCTACATCATCAAAAATAAGCCCCCTGAAGTATTAGCAAAATTTCAAAC
CCTTGATATTTCTGATGTGGGGATTTCATCAATTACTGTTGCAGAACTGGAATATGGCGTTTATAAAAGTCAGCGTCAAG
AGCAAAACCGTGCAGCACTTTCTCAATTTTTAATTCCTCTAGAAATCCTACCTTTTGATACACAATCAACACAAACCTAT
GGAAGACTTCGAGCAGAATTAGAACGTCAAGGAATAGCAATTGGTTCAATGGATATGCTCATAGCATCTCAAGCAATTGC
TCTTGGATTAATATTGGTGACAAATAATCTCAGAGAACTATCAAGAATTCCAGAATTAGTATTGGAAAATTGGGTCAATT
AA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8573.74 Da        Isoelectric Point: 4.9004

>AT31724 WP_096626566.1 NZ_AP018254:c5754335-5754108 [Calothrix sp. NIES-3974]
MNTAQLITNGDKQTVILPKGFQFQGSEVYIKKVGNAVVLISKDNPWQTLFDSLNLFSDDFMPTREQPNLDRRETL

Download         Length: 228 bp

>AT31724 NZ_AP018254:c5754335-5754108 [Calothrix sp. NIES-3974]
ATGAATACCGCTCAACTGATCACAAACGGTGACAAGCAAACCGTAATTCTACCTAAAGGATTTCAGTTTCAAGGGTCTGA
AGTTTACATTAAAAAAGTCGGTAATGCTGTTGTTCTAATTTCCAAAGATAATCCTTGGCAAACATTATTTGATAGCTTAA
ATCTTTTTTCTGATGATTTTATGCCAACTAGAGAACAACCCAATTTAGACAGAAGAGAAACATTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References