Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/DUF433(antitoxin) |
Location | 2061045..2061607 | Replicon | chromosome |
Accession | NZ_AP018203 | ||
Organism | Leptolyngbya boryana NIES-2135 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | A0A1Z4JEA4 |
Locus tag | CA740_RS09415 | Protein ID | WP_017286620.1 |
Coordinates | 2061266..2061607 (+) | Length | 114 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | A0A1Z4JEC0 |
Locus tag | CA740_RS09410 | Protein ID | WP_017286619.1 |
Coordinates | 2061045..2061269 (+) | Length | 75 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CA740_RS09395 | 2057709..2058398 | - | 690 | WP_017286616.1 | glycoside hydrolase family protein | - |
CA740_RS09400 | 2058464..2060098 | - | 1635 | WP_017286617.1 | ABC transporter ATP-binding protein | - |
CA740_RS09405 | 2060148..2060834 | - | 687 | WP_017286618.1 | SEC59/DGK1/VTE5 family protein | - |
CA740_RS09410 | 2061045..2061269 | + | 225 | WP_017286619.1 | DUF433 domain-containing protein | Antitoxin |
CA740_RS09415 | 2061266..2061607 | + | 342 | WP_017286620.1 | DUF5615 family PIN-like protein | Toxin |
CA740_RS09420 | 2061652..2062473 | - | 822 | WP_017286621.1 | slipin family protein | - |
CA740_RS09425 | 2062566..2063492 | - | 927 | WP_017286622.1 | branched-chain amino acid ABC transporter permease | - |
CA740_RS09430 | 2063489..2064439 | - | 951 | WP_017286623.1 | branched-chain amino acid ABC transporter permease | - |
CA740_RS09435 | 2064481..2065665 | - | 1185 | WP_017286624.1 | ABC transporter substrate-binding protein | - |
CA740_RS09440 | 2065730..2066440 | - | 711 | WP_017286625.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12378.18 Da Isoelectric Point: 4.1314
>T31719 WP_017286620.1 NZ_AP018203:2061266-2061607 [Leptolyngbya boryana NIES-2135]
VTTIWIDAHLSPVIATWITGRFGITAIALRDIGLRDAEDPEIFEAAKAQGVIFMTKDSDFVDLVERLEAPPQIIWLTCGN
TSNARLQEILSSTLPDALELLKSGEKLVEISGE
VTTIWIDAHLSPVIATWITGRFGITAIALRDIGLRDAEDPEIFEAAKAQGVIFMTKDSDFVDLVERLEAPPQIIWLTCGN
TSNARLQEILSSTLPDALELLKSGEKLVEISGE
Download Length: 342 bp
>T31719 NZ_AP018203:2061266-2061607 [Leptolyngbya boryana NIES-2135]
GTGACAACGATTTGGATCGATGCCCATTTGTCGCCTGTGATCGCAACTTGGATTACAGGCAGATTTGGAATTACCGCGAT
CGCTTTACGGGATATCGGCTTGAGAGATGCCGAAGATCCCGAAATCTTTGAGGCTGCAAAAGCTCAAGGCGTTATATTCA
TGACTAAAGATAGCGATTTCGTGGATCTCGTTGAACGTTTGGAAGCACCGCCACAAATTATTTGGTTAACTTGTGGCAAT
ACATCAAATGCCCGTTTGCAGGAAATTCTAAGCTCGACTTTGCCTGATGCATTAGAGTTATTGAAATCTGGCGAAAAGCT
AGTAGAGATTAGCGGAGAGTAA
GTGACAACGATTTGGATCGATGCCCATTTGTCGCCTGTGATCGCAACTTGGATTACAGGCAGATTTGGAATTACCGCGAT
CGCTTTACGGGATATCGGCTTGAGAGATGCCGAAGATCCCGAAATCTTTGAGGCTGCAAAAGCTCAAGGCGTTATATTCA
TGACTAAAGATAGCGATTTCGTGGATCTCGTTGAACGTTTGGAAGCACCGCCACAAATTATTTGGTTAACTTGTGGCAAT
ACATCAAATGCCCGTTTGCAGGAAATTCTAAGCTCGACTTTGCCTGATGCATTAGAGTTATTGAAATCTGGCGAAAAGCT
AGTAGAGATTAGCGGAGAGTAA
Antitoxin
Download Length: 75 a.a. Molecular weight: 8186.57 Da Isoelectric Point: 7.8330
>AT31719 WP_017286619.1 NZ_AP018203:2061045-2061269 [Leptolyngbya boryana NIES-2135]
MSDLLKRITVNPKQCGGRPCIRGMRIRVSDVLDLFAAGLSAEQILEELPDLERDDLRAALAYASRKVNHPVLVA
MSDLLKRITVNPKQCGGRPCIRGMRIRVSDVLDLFAAGLSAEQILEELPDLERDDLRAALAYASRKVNHPVLVA
Download Length: 225 bp
>AT31719 NZ_AP018203:2061045-2061269 [Leptolyngbya boryana NIES-2135]
ATGTCAGACTTACTTAAACGAATCACCGTGAATCCTAAGCAATGTGGGGGTCGCCCCTGTATTCGTGGCATGAGAATTCG
AGTGTCCGATGTTTTGGATTTATTTGCAGCAGGGTTAAGTGCTGAACAAATTTTGGAAGAACTGCCTGATCTGGAAAGAG
ATGATTTAAGAGCAGCACTTGCCTACGCTTCACGTAAAGTCAACCACCCTGTTTTAGTCGCGTGA
ATGTCAGACTTACTTAAACGAATCACCGTGAATCCTAAGCAATGTGGGGGTCGCCCCTGTATTCGTGGCATGAGAATTCG
AGTGTCCGATGTTTTGGATTTATTTGCAGCAGGGTTAAGTGCTGAACAAATTTTGGAAGAACTGCCTGATCTGGAAAGAG
ATGATTTAAGAGCAGCACTTGCCTACGCTTCACGTAAAGTCAACCACCCTGTTTTAGTCGCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1Z4JEA4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1Z4JEC0 |