Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 1616839..1617472 Replicon chromosome
Accession NZ_AP018112
Organism Burkholderia stabilis strain FERMP-21014

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BSFP_RS24355 Protein ID WP_096474391.1
Coordinates 1616839..1617252 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BSFP_RS24360 Protein ID WP_096474392.1
Coordinates 1617239..1617472 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSFP_RS24335 1612669..1613976 + 1308 WP_096474388.1 shikimate transporter -
BSFP_RS24340 1614180..1615481 + 1302 WP_047903294.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
BSFP_RS24345 1615610..1616221 - 612 WP_096474389.1 hypothetical protein -
BSFP_RS24350 1616401..1616796 + 396 WP_096474390.1 DUF4440 domain-containing protein -
BSFP_RS24355 1616839..1617252 - 414 WP_096474391.1 PIN domain-containing protein Toxin
BSFP_RS24360 1617239..1617472 - 234 WP_096474392.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BSFP_RS24365 1617633..1618403 + 771 WP_096474393.1 helix-turn-helix domain-containing protein -
BSFP_RS24370 1618501..1620801 - 2301 WP_096474394.1 ATP-dependent DNA helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(10-119)

Antitoxin

SpoVT-AbrB domain

(5-37)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15225.38 Da        Isoelectric Point: 5.1973

>T31703 WP_096474391.1 NZ_AP018112:c1617252-1616839 [Burkholderia stabilis]
MSGVESAKSFVDSNVVLYLLSEDETKANRAEALFLRRPTISVQVLNEVASVCSRKLRMPWSDVGQFLEPIRSLCHVVPVT
IDTHDLARRLAERHGLSFYDACIVAAASLEGCEYLYTEDMHDGLRVDGGPVLRNPFA

Download         Length: 414 bp

>T31703 NZ_AP018112:c1617252-1616839 [Burkholderia stabilis]
ATGAGCGGGGTTGAGTCGGCGAAATCGTTCGTCGACAGCAATGTCGTGCTTTATCTGCTGTCCGAGGACGAAACCAAGGC
GAATCGTGCGGAGGCACTGTTCCTTCGGCGGCCCACCATCAGTGTCCAGGTACTGAACGAGGTCGCCAGCGTTTGCAGCC
GAAAATTGCGGATGCCGTGGAGCGACGTGGGGCAGTTTCTGGAACCGATCAGGAGCTTGTGCCATGTCGTACCGGTCACG
ATCGATACGCATGACCTGGCGCGAAGGCTGGCGGAACGGCATGGCTTGTCCTTCTATGACGCGTGCATCGTCGCCGCCGC
GTCGCTCGAGGGCTGCGAGTACCTGTACACCGAGGACATGCACGACGGCCTGCGCGTGGACGGCGGTCCGGTGCTGCGAA
ATCCGTTTGCCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8750.99 Da        Isoelectric Point: 10.2843

>AT31703 WP_096474392.1 NZ_AP018112:c1617472-1617239 [Burkholderia stabilis]
MQVAKWGNSLAVRLPASVVDALELREGDDIEIVVDSPRVFAVSRKPRADELLQRLRRFRGKLPADFKFSRDDANERG

Download         Length: 234 bp

>AT31703 NZ_AP018112:c1617472-1617239 [Burkholderia stabilis]
ATGCAGGTCGCAAAGTGGGGCAATAGCCTGGCCGTCCGCCTTCCCGCCAGTGTCGTCGATGCACTGGAGCTCCGCGAAGG
GGACGATATCGAAATCGTCGTCGATAGTCCGCGCGTTTTTGCCGTCAGCCGCAAGCCGAGGGCCGATGAACTTCTGCAAC
GGTTGCGGCGTTTCAGGGGCAAGCTGCCCGCCGATTTCAAGTTCAGCCGGGACGACGCGAATGAGCGGGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References