Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1402731..1403370 Replicon chromosome
Accession NZ_AP018112
Organism Burkholderia stabilis strain FERMP-21014

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BSFP_RS23425 Protein ID WP_172902977.1
Coordinates 1402954..1403370 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BSFP_RS23420 Protein ID WP_096475613.1
Coordinates 1402731..1402967 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSFP_RS23395 1397945..1398172 + 228 WP_096474226.1 hypothetical protein -
BSFP_RS23400 1398183..1399226 + 1044 WP_096474228.1 ferredoxin--NADP reductase -
BSFP_RS23405 1399274..1400854 + 1581 WP_172903011.1 FadD3 family acyl-CoA ligase -
BSFP_RS23410 1400887..1401660 + 774 WP_096474230.1 SDR family oxidoreductase -
BSFP_RS23420 1402731..1402967 + 237 WP_096475613.1 DNA-binding protein Antitoxin
BSFP_RS23425 1402954..1403370 + 417 WP_172902977.1 type II toxin-antitoxin system VapC family toxin Toxin
BSFP_RS23430 1403619..1405151 - 1533 WP_157776402.1 hypothetical protein -
BSFP_RS23435 1405872..1406768 + 897 WP_096474236.1 VOC family protein -
BSFP_RS23440 1406778..1407671 + 894 WP_096474238.1 CoA transferase subunit A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15324.61 Da        Isoelectric Point: 7.4037

>T31701 WP_172902977.1 NZ_AP018112:1402954-1403370 [Burkholderia stabilis]
VFLIDTNVISEIRKGKRTNRGVRAFFRQAEADASPLYLSVVTVAELRRGVDLIRHRGDHPQASALEAWMATILSGYAPNI
LPVDIEISQMWGHLRVPDPAHELDKLIAATALINDLTVVTRNVGDFARTGVRLLNPFD

Download         Length: 417 bp

>T31701 NZ_AP018112:1402954-1403370 [Burkholderia stabilis]
GTGTTTTTGATTGATACGAACGTCATCAGCGAAATCAGGAAGGGCAAGCGAACCAACCGCGGCGTGCGGGCGTTCTTCAG
GCAGGCCGAGGCCGACGCGAGCCCGCTTTACCTGTCCGTCGTGACGGTGGCCGAACTTCGGCGCGGTGTCGACCTGATCC
GTCATCGCGGCGATCACCCCCAGGCGTCGGCGCTCGAGGCATGGATGGCGACGATCCTGTCGGGCTATGCACCGAACATC
CTGCCGGTCGATATCGAGATCAGCCAGATGTGGGGGCATTTACGCGTGCCCGATCCGGCGCACGAACTCGACAAACTGAT
CGCGGCCACCGCGCTGATCAACGATCTCACCGTCGTCACGCGCAATGTCGGCGATTTCGCTCGCACCGGCGTCCGGCTGC
TGAACCCGTTCGACTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8698.73 Da        Isoelectric Point: 4.7377

>AT31701 WP_096475613.1 NZ_AP018112:1402731-1402967 [Burkholderia stabilis]
MANLLVRNVDDSIVQSLREQAAANGRSAEAEHRAILADALGWPKRRTFAQVLMSMPDVGEDADFQRVQDSGEVRRVFD

Download         Length: 237 bp

>AT31701 NZ_AP018112:1402731-1402967 [Burkholderia stabilis]
ATGGCAAATCTTCTGGTGCGTAACGTGGATGACAGTATCGTTCAGAGCCTGCGCGAGCAGGCTGCGGCAAATGGCAGGAG
TGCCGAGGCCGAACATCGGGCCATTCTGGCCGATGCGCTCGGCTGGCCGAAGCGAAGGACATTTGCGCAAGTGCTGATGA
GCATGCCCGATGTTGGCGAAGACGCGGATTTCCAACGTGTTCAGGATTCCGGCGAGGTAAGGCGTGTTTTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References