Detailed information of TA system TA031701

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 1402731..1403370
• Replicon: chromosome
• Accession: NZ_AP018112
• Organism: Burkholderia stabilis strain FERMP-21014

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: BSFP_RS23425
• Protein ID: WP_172902977.1
• Coordinates: 1402954..1403370 (+)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: BSFP_RS23420
• Protein ID: WP_096475613.1
• Coordinates: 1402731..1402967 (+)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSFP_RS23395	1397945..1398172	+	228	WP_096474226.1	hypothetical protein	-
BSFP_RS23400	1398183..1399226	+	1044	WP_096474228.1	ferredoxin--NADP reductase	-
BSFP_RS23405	1399274..1400854	+	1581	WP_172903011.1	FadD3 family acyl-CoA ligase	-
BSFP_RS23410	1400887..1401660	+	774	WP_096474230.1	SDR family oxidoreductase	-
BSFP_RS23420	1402731..1402967	+	237	WP_096475613.1	DNA-binding protein	Antitoxin
BSFP_RS23425	1402954..1403370	+	417	WP_172902977.1	type II toxin-antitoxin system VapC family toxin	Toxin
BSFP_RS23430	1403619..1405151	-	1533	WP_157776402.1	hypothetical protein	-
BSFP_RS23435	1405872..1406768	+	897	WP_096474236.1	VOC family protein	-
BSFP_RS23440	1406778..1407671	+	894	WP_096474238.1	CoA transferase subunit A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-123)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 15324.61 Da
• Isoelectric Point: 7.4037

>T31701 WP_172902977.1 NZ_AP018112:1402954-1403370 [Burkholderia stabilis]
VFLIDTNVISEIRKGKRTNRGVRAFFRQAEADASPLYLSVVTVAELRRGVDLIRHRGDHPQASALEAWMATILSGYAPNI
LPVDIEISQMWGHLRVPDPAHELDKLIAATALINDLTVVTRNVGDFARTGVRLLNPFD

Nucleotide

• Length: 417 bp

>T31701 NZ_AP018112:1402954-1403370 [Burkholderia stabilis]
GTGTTTTTGATTGATACGAACGTCATCAGCGAAATCAGGAAGGGCAAGCGAACCAACCGCGGCGTGCGGGCGTTCTTCAG
GCAGGCCGAGGCCGACGCGAGCCCGCTTTACCTGTCCGTCGTGACGGTGGCCGAACTTCGGCGCGGTGTCGACCTGATCC
GTCATCGCGGCGATCACCCCCAGGCGTCGGCGCTCGAGGCATGGATGGCGACGATCCTGTCGGGCTATGCACCGAACATC
CTGCCGGTCGATATCGAGATCAGCCAGATGTGGGGGCATTTACGCGTGCCCGATCCGGCGCACGAACTCGACAAACTGAT
CGCGGCCACCGCGCTGATCAACGATCTCACCGTCGTCACGCGCAATGTCGGCGATTTCGCTCGCACCGGCGTCCGGCTGC
TGAACCCGTTCGACTAG

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8698.73 Da
• Isoelectric Point: 4.7377

>AT31701 WP_096475613.1 NZ_AP018112:1402731-1402967 [Burkholderia stabilis]
MANLLVRNVDDSIVQSLREQAAANGRSAEAEHRAILADALGWPKRRTFAQVLMSMPDVGEDADFQRVQDSGEVRRVFD

Nucleotide

• Length: 237 bp

>AT31701 NZ_AP018112:1402731-1402967 [Burkholderia stabilis]
ATGGCAAATCTTCTGGTGCGTAACGTGGATGACAGTATCGTTCAGAGCCTGCGCGAGCAGGCTGCGGCAAATGGCAGGAG
TGCCGAGGCCGAACATCGGGCCATTCTGGCCGATGCGCTCGGCTGGCCGAAGCGAAGGACATTTGCGCAAGTGCTGATGA
GCATGCCCGATGTTGGCGAAGACGCGGATTTCCAACGTGTTCAGGATTCCGGCGAGGTAAGGCGTGTTTTTGATTGA