Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1152786..1154533 Replicon chromosome
Accession NZ_AP018112
Organism Burkholderia stabilis strain FERMP-21014

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag BSFP_RS22300 Protein ID WP_096473993.1
Coordinates 1152786..1153682 (+) Length 299 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag BSFP_RS22305 Protein ID WP_096473994.1
Coordinates 1153679..1154533 (+) Length 285 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSFP_RS22270 1148164..1149243 - 1080 WP_096473990.1 porin -
BSFP_RS22275 1149691..1150008 + 318 WP_006489883.1 non-heme iron oxygenase ferredoxin subunit -
BSFP_RS22280 1150010..1150321 + 312 WP_034180372.1 hypothetical protein -
BSFP_RS22285 1150377..1151447 + 1071 WP_096473991.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
BSFP_RS22290 1151440..1152210 + 771 WP_096473992.1 SDR family oxidoreductase -
BSFP_RS22295 1152240..1152767 + 528 WP_006489904.1 cupin domain-containing protein -
BSFP_RS22300 1152786..1153682 + 897 WP_096473993.1 alpha/beta fold hydrolase Toxin
BSFP_RS22305 1153679..1154533 + 855 WP_096473994.1 IclR family transcriptional regulator Antitoxin
BSFP_RS22310 1154610..1155407 + 798 WP_096473995.1 SDR family oxidoreductase -
BSFP_RS22315 1155400..1157067 + 1668 WP_096473996.1 thiamine pyrophosphate-binding protein -
BSFP_RS22320 1157060..1157875 + 816 WP_096473997.1 aspartate dehydrogenase -
BSFP_RS22325 1157965..1159455 + 1491 WP_096473998.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(51-277)

Antitoxin

Transcription regulator IclR, C-terminal

(142-265)


Sequences

Toxin        


Download         Length: 299 a.a.        Molecular weight: 30608.80 Da        Isoelectric Point: 7.7326

>T31700 WP_096473993.1 NZ_AP018112:1152786-1153682 [Burkholderia stabilis]
MSVVDKRERDRTAAFAALLGQFPEQRCAAGAAGTIGYREAGAQHAGRALPVVLLHGIGSGAASWVRQLDALGVSRRVLAW
DAPGYGASTPVHGASPAAADYAASLNAWLEALGIERCVLVGHSLGAIVAGGLARVMPGRIAGLLLVSPAGGYGSAPAETR
ESRRDARLAMLAELGPAGLAEQRSGNMLSGFASEDARAWVRWNMARIVPAGYAQATHLLANADLATDLAGFRGRTAVAVG
ANDAITPPAACERIAAAAHVGLQVIPQAGHAGYVEAPSVYSALIDTFCRQCDTQWGLA

Download         Length: 897 bp

>T31700 NZ_AP018112:1152786-1153682 [Burkholderia stabilis]
ATGAGTGTCGTCGACAAACGTGAACGCGACCGCACCGCGGCATTCGCCGCGCTGCTCGGGCAGTTTCCCGAGCAGCGTTG
CGCGGCCGGCGCGGCGGGCACGATCGGATATCGCGAGGCCGGCGCGCAGCATGCGGGCCGCGCGCTGCCCGTCGTGCTGC
TGCACGGGATCGGCTCGGGCGCCGCATCGTGGGTGCGCCAGCTCGACGCGCTCGGTGTATCGCGCCGCGTGCTCGCGTGG
GATGCGCCCGGTTATGGCGCGTCGACGCCCGTGCACGGCGCGTCGCCGGCTGCCGCCGATTACGCGGCGTCGCTGAACGC
GTGGCTCGAGGCACTCGGCATCGAACGCTGCGTGCTGGTCGGGCATTCGCTCGGCGCGATCGTCGCGGGCGGTCTCGCCC
GCGTGATGCCCGGGCGGATCGCCGGCCTGCTGCTGGTGTCGCCCGCGGGCGGCTACGGCAGCGCGCCCGCCGAAACGCGC
GAATCGCGCCGCGACGCGCGGCTCGCGATGCTCGCGGAACTCGGCCCGGCCGGGCTCGCCGAGCAGCGCAGCGGCAACAT
GCTGTCCGGTTTCGCGAGCGAGGATGCGCGCGCGTGGGTGCGCTGGAACATGGCGCGCATCGTGCCGGCCGGCTATGCGC
AGGCCACGCATCTGCTCGCGAACGCCGATCTCGCGACCGATCTCGCCGGTTTTCGCGGCCGCACGGCCGTGGCCGTCGGC
GCGAACGACGCGATCACGCCGCCCGCCGCATGCGAGCGGATCGCCGCGGCCGCGCACGTCGGGTTGCAGGTGATTCCGCA
AGCCGGTCATGCCGGATACGTGGAAGCGCCGTCCGTTTATTCCGCACTGATCGACACGTTCTGCCGTCAGTGCGATACGC
AGTGGGGTCTGGCATGA

Antitoxin


Download         Length: 285 a.a.        Molecular weight: 31288.81 Da        Isoelectric Point: 6.5086

>AT31700 WP_096473994.1 NZ_AP018112:1153679-1154533 [Burkholderia stabilis]
MSEPLQQEPENGKAEASYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYKL
GIAVLRLGFEYLSSLELTDLGLPVIESLRDATGFTTHIVIRDGRDVVFVAKAQSQSPVFSSIRVNVGTRLPAYATTHGHV
LMGDLSLKELRSLYPEGTLNRMTSATPETVDALYEVIREDALRGYGVSNSSFERGISVVTAPVRNETQKIVACITVTVPR
PEIDAALIADGLIDKVQRAAAELSRRLNYRSDDEHTFLKALGLK

Download         Length: 855 bp

>AT31700 NZ_AP018112:1153679-1154533 [Burkholderia stabilis]
ATGAGCGAACCGCTGCAACAAGAACCCGAAAACGGGAAGGCCGAGGCCAGCTACGTGGTGCCGGGCCTCGAGCGCGGGCT
GCGGATTCTCGCCGAATTCTCGCCGCGCGAGCCGGTGCTCGGCGCGCCCGAGTTGTCGAAGCGGCTCGGCATTCCGCGCA
CGACGGTGTTCCGTCTGCTTCAGACGCTCGAATCGCTGGGCTTCCTCGAGCGCGCGGACAAGGATCGCAACTACAAGCTC
GGTATCGCCGTGCTGCGGCTCGGCTTCGAATACCTGAGTTCGCTGGAGCTGACCGATCTCGGCCTGCCGGTGATCGAGAG
CCTGCGCGACGCGACCGGCTTCACGACGCACATCGTGATCCGCGACGGCCGCGACGTCGTGTTCGTCGCGAAGGCGCAGA
GCCAGTCGCCGGTGTTCAGCTCGATCCGCGTGAACGTCGGCACACGCTTGCCCGCGTATGCGACGACGCACGGTCACGTG
CTGATGGGCGACCTGTCGCTGAAGGAGCTGCGCTCGCTGTATCCGGAGGGCACGCTGAACCGGATGACGAGCGCGACGCC
GGAGACGGTCGATGCGTTGTACGAAGTGATCCGCGAGGATGCGCTGCGCGGCTACGGCGTCAGCAATTCGTCGTTCGAGC
GCGGCATCTCGGTGGTCACGGCGCCCGTGCGCAACGAGACGCAGAAGATCGTCGCGTGCATCACGGTGACGGTGCCGCGG
CCGGAGATCGACGCGGCGCTGATCGCGGACGGGTTGATCGACAAGGTGCAGCGCGCGGCGGCGGAACTGTCGCGGCGGCT
CAATTACCGCTCGGATGACGAGCACACGTTTTTGAAGGCTTTAGGATTGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References