Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 801872..803101 Replicon chromosome
Accession NZ_AP018112
Organism Burkholderia stabilis strain FERMP-21014

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BSFP_RS20640 Protein ID WP_096473723.1
Coordinates 801872..802453 (-) Length 194 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BSFP_RS20645 Protein ID WP_096473724.1
Coordinates 802535..803101 (-) Length 189 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSFP_RS20625 796978..798351 - 1374 WP_096473721.1 efflux transporter outer membrane subunit -
BSFP_RS20630 798365..800389 - 2025 WP_096473722.1 MacB family efflux pump subunit -
BSFP_RS20635 800392..801585 - 1194 WP_096475568.1 efflux RND transporter periplasmic adaptor subunit -
BSFP_RS20640 801872..802453 - 582 WP_096473723.1 HD domain-containing protein Toxin
BSFP_RS20645 802535..803101 - 567 WP_096473724.1 helix-turn-helix domain-containing protein Antitoxin
BSFP_RS20650 803187..803825 - 639 WP_096473725.1 hypothetical protein -
BSFP_RS35850 803828..804178 + 351 WP_157776392.1 hypothetical protein -
BSFP_RS20655 804191..805594 + 1404 WP_096473726.1 hypothetical protein -
BSFP_RS20660 805689..806267 + 579 WP_096473727.1 hypothetical protein -
BSFP_RS20665 806508..807239 + 732 WP_096473728.1 ribonuclease T2 -
BSFP_RS20670 807478..808068 - 591 WP_096473729.1 cysteine hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(6-157)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 194 a.a.        Molecular weight: 21334.89 Da        Isoelectric Point: 5.2861

>T31697 WP_096473723.1 NZ_AP018112:c802453-801872 [Burkholderia stabilis]
MNPDTIHARLDFLREAERLKDVLRSGHTSAGRAESTAEHSWRLCLMALVFADALPGIDTLKLLKLCVVHDLGEALHGDIP
AIEQAAHPDKSAHERDDLLTLTTSLDRTLRDEIVALWDEYEAAASPEARAAKALDKLETILQHNQGSNPPDFDYAFNLGY
GRRHTDAAPLFSAIRDIVDADTQRRIDAGGHRA

Download         Length: 582 bp

>T31697 NZ_AP018112:c802453-801872 [Burkholderia stabilis]
ATGAACCCCGACACGATCCACGCGCGGCTCGATTTCCTGCGCGAAGCCGAACGCCTGAAGGACGTGCTGCGCAGCGGCCA
CACGTCGGCCGGGCGCGCGGAAAGCACGGCCGAGCATAGCTGGCGGCTGTGCCTGATGGCGCTCGTGTTCGCCGACGCGC
TGCCCGGCATCGATACGCTGAAGCTGCTGAAACTGTGCGTCGTCCACGATCTCGGCGAGGCGCTGCACGGCGACATCCCC
GCGATCGAACAGGCCGCGCACCCGGACAAAAGCGCGCACGAACGCGACGACCTGCTGACGCTGACGACGTCGCTCGATCG
CACGCTGCGCGACGAGATCGTCGCGCTGTGGGATGAATACGAGGCGGCCGCGTCGCCGGAAGCACGTGCGGCGAAGGCGC
TCGACAAGCTCGAGACGATCCTGCAGCACAACCAGGGCAGCAATCCGCCCGATTTCGACTACGCGTTCAATCTCGGCTAC
GGCCGGCGCCATACCGACGCCGCGCCGCTGTTCAGTGCGATCCGCGATATCGTCGATGCCGATACCCAACGCAGGATCGA
CGCGGGCGGGCACCGCGCGTAA

Antitoxin


Download         Length: 189 a.a.        Molecular weight: 20326.30 Da        Isoelectric Point: 10.7146

>AT31697 WP_096473724.1 NZ_AP018112:c803101-802535 [Burkholderia stabilis]
MTAPALHTPPLGPQLKRWRALHRVKQSHAAELFGVAQSTISRWEAGIQQMSPGERATAERLLAARLDSAGDHALARLIAG
SAGSAGRMHLVCDLTHRLLASSPARAAEFSQPLSMLLGTSLWRYATPEIVRMETALDTLGWHDRAGPPSVEFDTGANASR
VVPIRGSTCRWTRMMLSDGSAARLVETL

Download         Length: 567 bp

>AT31697 NZ_AP018112:c803101-802535 [Burkholderia stabilis]
ATGACCGCCCCAGCGCTTCACACACCACCGCTCGGCCCGCAGCTCAAGCGCTGGCGCGCGCTGCACCGCGTGAAGCAAAG
CCACGCCGCAGAACTGTTCGGCGTCGCGCAATCGACGATCTCCCGCTGGGAAGCCGGTATCCAGCAGATGTCGCCCGGCG
AGCGCGCGACGGCCGAGCGGCTGCTCGCCGCGCGCCTCGATTCCGCGGGCGACCACGCGCTCGCGCGGCTCATCGCGGGC
AGCGCGGGCAGCGCGGGCCGCATGCATCTCGTGTGCGATCTCACGCATCGCCTGCTCGCAAGCTCGCCGGCGCGCGCGGC
CGAGTTCTCGCAGCCGCTTTCGATGCTGCTCGGCACGTCGCTGTGGCGCTACGCGACACCGGAAATAGTCCGCATGGAAA
CCGCGCTCGACACGCTCGGCTGGCATGATCGCGCGGGGCCGCCGAGCGTCGAATTCGATACCGGCGCGAATGCGTCGCGC
GTCGTGCCGATCCGCGGCAGCACATGCCGGTGGACGCGGATGATGCTGTCGGACGGTTCGGCCGCGCGGCTCGTGGAAAC
GCTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References