Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 461468..462002 Replicon chromosome
Accession NZ_AP018111
Organism Burkholderia stabilis strain FERMP-21014

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BSFP_RS01910 Protein ID WP_096470897.1
Coordinates 461703..462002 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag BSFP_RS01905 Protein ID WP_096470896.1
Coordinates 461468..461713 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSFP_RS01880 456704..457120 + 417 WP_027787436.1 PIN domain-containing protein -
BSFP_RS01885 457169..458074 - 906 WP_096470893.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
BSFP_RS01890 458043..459116 - 1074 WP_096473011.1 hypothetical protein -
BSFP_RS01895 459459..460622 + 1164 WP_096470894.1 amidohydrolase -
BSFP_RS01900 460808..461347 + 540 WP_096470895.1 outer membrane protein assembly factor BamE -
BSFP_RS01905 461468..461713 + 246 WP_096470896.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BSFP_RS01910 461703..462002 + 300 WP_096470897.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSFP_RS01915 462063..463367 - 1305 WP_096470898.1 cobyrinate a,c-diamide synthase -
BSFP_RS01920 463370..463972 - 603 WP_096470899.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
BSFP_RS01925 464007..464384 - 378 WP_096470900.1 cobalamin biosynthesis protein -
BSFP_RS01930 464381..465190 - 810 WP_172902901.1 uroporphyrinogen-III C-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11594.24 Da        Isoelectric Point: 8.0947

>T31695 WP_096470897.1 NZ_AP018111:461703-462002 [Burkholderia stabilis]
MAVKGRQLRLTPLAEIDLEDIWRYTAEQWSLAQADRYHRDLIGTMEALARGKKAGRTCIARDGYFRYAVGSHVVFHRETD
DTIDVIRVLHQRMDIERHL

Download         Length: 300 bp

>T31695 NZ_AP018111:461703-462002 [Burkholderia stabilis]
ATGGCGGTTAAAGGCCGACAGCTTCGGCTGACTCCGCTGGCCGAGATCGATCTCGAAGACATCTGGCGGTATACCGCCGA
GCAATGGTCGCTCGCGCAGGCGGATCGCTACCACCGCGATCTGATCGGGACGATGGAAGCGCTGGCGCGCGGGAAAAAGG
CTGGCCGGACTTGCATTGCTCGGGACGGGTATTTCCGGTACGCAGTGGGTTCCCATGTCGTGTTCCATCGCGAAACAGAT
GACACGATCGATGTGATTCGAGTCCTCCATCAGCGGATGGATATCGAACGACACCTGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8692.64 Da        Isoelectric Point: 6.7232

>AT31695 WP_096470896.1 NZ_AP018111:461468-461713 [Burkholderia stabilis]
MSRNTSVSLGDHFAAFVDAQVQSGRYGSASDVVRAGLRLLESHETQMRALQEALKAGEASGEPRPFDSEAFLARMRATHG
G

Download         Length: 246 bp

>AT31695 NZ_AP018111:461468-461713 [Burkholderia stabilis]
ATGTCGCGAAACACATCCGTTTCCCTGGGCGACCACTTTGCCGCATTCGTCGACGCTCAAGTGCAATCGGGGCGATATGG
TTCCGCAAGTGACGTCGTGCGAGCCGGCTTGCGGCTCCTCGAGTCACACGAAACGCAAATGCGTGCGTTGCAGGAAGCGT
TGAAGGCCGGCGAGGCATCAGGAGAGCCACGGCCCTTCGACAGCGAGGCCTTCCTGGCCCGCATGCGGGCAACGCATGGC
GGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References