Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 161382..162916 Replicon plasmid pANY103b
Accession NZ_AP017988
Organism Aminobacter sp. SS-2016 strain Y103A

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag Amn_RS30695 Protein ID WP_286299119.1
Coordinates 161993..162916 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag Amn_RS30690 Protein ID WP_286299116.1
Coordinates 161382..161996 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Amn_RS30685 (Amn_pb01430) 157227..161297 - 4071 WP_286299114.1 helix-turn-helix transcriptional regulator -
Amn_RS30690 (Amn_pb01440) 161382..161996 + 615 WP_286299116.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
Amn_RS30695 (Amn_pb01450) 161993..162916 + 924 WP_286299119.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
Amn_RS30700 (Amn_pb01460) 163418..163990 + 573 Protein_158 transposase -
Amn_RS30705 (Amn_pb01480) 164327..164740 - 414 WP_286299121.1 nuclear transport factor 2 family protein -
Amn_RS30710 (Amn_pb01490) 165378..167519 + 2142 WP_286299124.1 DUF87 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..300871 300871
- flank IS/Tn - - 163382..163990 608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-275)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(11-55)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34507.77 Da        Isoelectric Point: 5.8723

>T31448 WP_286299119.1 NZ_AP017988:161993-162916 [Aminobacter sp. SS-2016]
MKDKVIKDPASSIRARLLADAKTNGDDFQRVLTRYAIERLLFRLSQTEAVEHYVLKGAMLFVTWPRHVLRPTGDLDLLGR
GDPAPEVLKELFTRICQVELADDGILFDPTTLQVEEVREADKYQGARLKLKAGLAGAVITVLIDIGFGDHVYPPPKRETF
PSLLSGLPEANILMYPPETVIAEKFEAMIRFGETNGRIKDFYDVWVTTRTFPFDLGSVVEAVGGTLRRRETVMPTDMPVG
LTDVFAAIAEERGLWAGFLRRSPPAMEPPPFRQLQEELRSFFRPIIASLSVPEGARGRWDPNGNAWR

Download         Length: 924 bp

>T31448 NZ_AP017988:161993-162916 [Aminobacter sp. SS-2016]
ATGAAAGATAAGGTCATCAAGGATCCTGCCTCATCGATCCGCGCGCGTCTGCTAGCTGACGCCAAAACGAATGGCGACGA
CTTTCAGCGGGTTCTGACGCGCTACGCCATTGAGCGGCTCCTGTTTCGTCTCAGCCAGACAGAAGCCGTAGAGCACTATG
TGCTGAAAGGTGCCATGCTATTCGTCACTTGGCCTAGGCATGTTCTTAGGCCCACCGGCGACCTGGACCTCCTCGGCCGA
GGCGACCCTGCCCCCGAGGTCTTGAAGGAATTGTTCACCCGCATTTGCCAGGTGGAGCTGGCAGACGACGGCATCCTATT
CGACCCGACTACGCTGCAGGTCGAGGAAGTGCGCGAAGCCGACAAATATCAGGGTGCGCGGCTGAAGTTGAAGGCCGGTC
TGGCCGGCGCAGTGATAACCGTGCTGATCGACATAGGCTTCGGCGACCACGTATACCCGCCGCCGAAAAGGGAAACTTTC
CCATCCCTGTTGTCTGGTCTACCGGAGGCCAACATCCTCATGTACCCGCCCGAGACTGTAATAGCCGAGAAGTTCGAGGC
GATGATCCGTTTTGGGGAGACCAACGGCCGAATAAAGGACTTCTACGACGTCTGGGTTACCACCCGCACTTTCCCGTTCG
ACCTGGGAAGCGTCGTCGAGGCAGTCGGCGGCACGCTGCGGCGCCGTGAGACTGTGATGCCGACGGACATGCCTGTGGGC
CTGACCGACGTCTTCGCCGCCATTGCAGAAGAGCGCGGCCTCTGGGCGGGCTTCCTGCGTAGGTCGCCTCCAGCGATGGA
GCCACCGCCTTTTCGGCAGCTGCAGGAGGAGCTGCGAAGCTTCTTCAGGCCGATCATCGCCAGCCTGAGTGTCCCGGAAG
GCGCTCGGGGACGTTGGGATCCCAATGGAAACGCTTGGCGCTGA

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 22826.56 Da        Isoelectric Point: 10.4465

>AT31448 WP_286299116.1 NZ_AP017988:161382-161996 [Aminobacter sp. SS-2016]
MTDLHMNYRERALDLVRARGIARARDFKAAGIPLVYLKRLTDSGVLVRLGRGLYQDSDRVGEHIEHNLAEAARLVPNGII
SLISALRHHELTTQLPNAVWMTIPHKDRTPKTTSLKFEIVRATGQALTAGIEQVIIEGVSVPVYGVAKTVADCFKHRRHV
GEDVAVEALRDALRQRKTTVSELMKFAVIDRVAGRMEPFMKAMQ

Download         Length: 615 bp

>AT31448 NZ_AP017988:161382-161996 [Aminobacter sp. SS-2016]
ATGACTGATCTTCATATGAATTATCGCGAACGCGCGCTCGATTTGGTCCGGGCACGAGGCATCGCGCGCGCGCGCGACTT
CAAGGCGGCCGGCATCCCGCTGGTCTATCTCAAGCGTCTGACCGACTCCGGCGTCCTAGTTCGTCTCGGCCGTGGACTCT
ACCAGGATTCCGACCGCGTTGGGGAGCATATCGAGCATAACTTGGCGGAGGCGGCGCGGCTGGTGCCTAACGGCATAATC
AGCCTCATAAGCGCGCTCCGTCACCACGAGCTAACGACCCAGCTTCCGAATGCCGTCTGGATGACCATTCCGCACAAAGA
TCGGACGCCGAAAACGACGAGCCTAAAGTTTGAGATTGTCCGGGCAACAGGCCAAGCCCTGACGGCGGGGATTGAGCAAG
TGATAATCGAAGGGGTCTCGGTACCGGTTTACGGCGTTGCCAAAACCGTCGCTGATTGCTTCAAGCACCGCCGTCATGTG
GGCGAGGATGTGGCGGTTGAGGCCCTTCGTGACGCACTAAGGCAGCGGAAGACCACCGTAAGCGAACTTATGAAGTTTGC
CGTCATCGACCGGGTCGCCGGCCGCATGGAGCCGTTCATGAAGGCCATGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References