31438

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 391435..392021 Replicon chromosome
Accession NZ_AP017959
Organism Synechococcus sp. NIES-970

Toxin (Protein)


Gene name PumA Uniprot ID A0A1Q2TUT9
Locus tag NIES970_RS01885 Protein ID WP_024545370.1
Coordinates 391731..392021 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NIES970_RS01880 Protein ID WP_096415897.1
Coordinates 391435..391722 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIES970_RS01860 387635..388705 + 1071 WP_096415888.1 tetratricopeptide repeat protein -
NIES970_RS01865 388732..389856 + 1125 WP_096415891.1 aldo/keto reductase -
NIES970_RS01870 389880..390200 - 321 WP_096415894.1 putative toxin-antitoxin system toxin component, PIN family -
NIES970_RS01875 390698..391330 - 633 WP_024545372.1 class I SAM-dependent methyltransferase -
NIES970_RS01880 391435..391722 - 288 WP_096415897.1 putative addiction module antidote protein Antitoxin
NIES970_RS01885 391731..392021 - 291 WP_024545370.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NIES970_RS01890 392201..393991 - 1791 WP_024545369.1 aspartate--tRNA ligase -
NIES970_RS01895 394045..394224 - 180 WP_096415900.1 hypothetical protein -
NIES970_RS01900 394255..394890 - 636 WP_024545367.1 peroxiredoxin -
NIES970_RS01905 395192..395608 + 417 WP_024545366.1 photosystem II complex extrinsic protein PsbU -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10966.70 Da        Isoelectric Point: 10.8825

>T31438 WP_024545370.1 NZ_AP017959:c392021-391731 [Synechococcus sp. NIES-970]
MIEIRETANYSRWFKSLRDRQAKARINIRIRRLSMGNPGDVKPVGKGVSELRIDYGPGYRVYFVQRGDMLVVLLAGGDKR
TQAQDIKTALELSQNL

Download         Length: 291 bp

>T31438 NZ_AP017959:c392021-391731 [Synechococcus sp. NIES-970]
ATGATCGAAATTCGCGAGACCGCAAATTATTCTCGATGGTTTAAATCACTGCGTGATCGGCAGGCTAAAGCCCGCATAAA
TATTCGTATTCGGCGATTGTCCATGGGGAATCCTGGTGATGTAAAGCCAGTGGGCAAAGGAGTGTCAGAACTTCGCATTG
ATTACGGCCCAGGATATCGAGTGTATTTTGTGCAACGAGGAGATATGTTGGTCGTACTGCTTGCGGGTGGAGATAAACGA
ACTCAAGCTCAGGATATCAAAACAGCCTTAGAGTTATCACAAAACCTATAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10292.83 Da        Isoelectric Point: 4.4550

>AT31438 WP_096415897.1 NZ_AP017959:c391722-391435 [Synechococcus sp. NIES-970]
MDKVLTSLWDAADHLETKEDMAAYLEAALEDGDPNLIIAALGDIARSKGMTSIARETGLGRESLYKALSFDGNPEFMTVL
KVVQALGLRLRATPI

Download         Length: 288 bp

>AT31438 NZ_AP017959:c391722-391435 [Synechococcus sp. NIES-970]
ATGGACAAAGTTTTAACGTCTCTCTGGGACGCGGCAGACCATTTAGAAACTAAGGAAGATATGGCGGCATATCTGGAGGC
AGCCCTTGAAGATGGGGATCCAAATCTTATCATCGCAGCATTAGGAGACATTGCAAGATCCAAAGGGATGACTAGTATTG
CGCGGGAAACAGGCTTAGGGCGTGAAAGTCTCTATAAAGCGTTATCTTTTGACGGAAACCCAGAATTTATGACTGTTTTA
AAAGTTGTTCAAGCTCTCGGTCTTCGTCTGCGAGCAACTCCCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Q2TUT9

Antitoxin

Source ID Structure

References