31355

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2201645..2202213 Replicon chromosome
Accession NZ_AP017898
Organism Sphingopyxis sp. FD7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SPYCA_RS10395 Protein ID WP_120220192.1
Coordinates 2201645..2202010 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SPYCA_RS10400 Protein ID WP_120222273.1
Coordinates 2202007..2202213 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SPYCA_RS10375 2197069..2197392 + 324 WP_120220184.1 YnfA family protein -
SPYCA_RS10380 2197533..2198246 - 714 WP_120220186.1 arylesterase -
SPYCA_RS10385 2198265..2198975 + 711 WP_120220188.1 ATP-binding cassette domain-containing protein -
SPYCA_RS10390 2199124..2201625 + 2502 WP_120220190.1 ABC transporter permease -
SPYCA_RS10395 2201645..2202010 - 366 WP_120220192.1 type II toxin-antitoxin system VapC family toxin Toxin
SPYCA_RS10400 2202007..2202213 - 207 WP_120222273.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
SPYCA_RS10405 2202523..2203281 - 759 WP_120220194.1 sulfite exporter TauE/SafE family protein -
SPYCA_RS10410 2203323..2204480 - 1158 WP_120220196.1 hypothetical protein -
SPYCA_RS10415 2204490..2205176 - 687 WP_120220198.1 helix-turn-helix domain-containing protein -
SPYCA_RS10420 2205173..2207176 - 2004 WP_120220200.1 threonine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(14-46)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13102.21 Da        Isoelectric Point: 6.7161

>T31355 WP_120220192.1 NZ_AP017898:c2202010-2201645 [Sphingopyxis sp. FD7]
MILIDSSVWIDHLRSANAGLALALSEGRVVQHPFVTAELALGSLASRDRFVAMLGLLSPAPVVETARLLDFITNRRLFGT
GLGMVDAHLLASTADMGAARLWTSDRRLAEQAERLGLLYQC

Download         Length: 366 bp

>T31355 NZ_AP017898:c2202010-2201645 [Sphingopyxis sp. FD7]
ATGATCCTGATCGACAGCTCGGTCTGGATCGATCATCTGCGCAGCGCCAATGCCGGGCTTGCGCTGGCGCTTTCCGAGGG
CCGCGTCGTCCAGCACCCGTTCGTCACGGCCGAACTGGCGCTCGGCTCGCTGGCCAGCCGCGACCGGTTCGTCGCGATGC
TTGGGTTGCTTTCGCCCGCGCCGGTGGTCGAAACCGCGCGCTTGCTCGATTTCATAACGAACCGGCGGCTGTTCGGCACC
GGGCTTGGCATGGTCGATGCCCATCTTTTGGCATCGACCGCCGATATGGGCGCCGCGCGGCTCTGGACCAGCGACCGGCG
GCTCGCGGAACAGGCGGAGCGGCTAGGCCTTCTTTATCAATGCTGA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7077.96 Da        Isoelectric Point: 11.0917

>AT31355 WP_120222273.1 NZ_AP017898:c2202213-2202007 [Sphingopyxis sp. FD7]
VRPQGQAAQQPAADLWAEAARITGIKDRGELERAAVRALIQREAARTLALMGGSDPGATAAPRERSGA

Download         Length: 207 bp

>AT31355 NZ_AP017898:c2202213-2202007 [Sphingopyxis sp. FD7]
GTGCGACCGCAGGGGCAGGCGGCTCAGCAACCGGCCGCCGATTTGTGGGCCGAGGCGGCGCGTATCACCGGCATCAAGGA
TCGCGGCGAGCTGGAGCGGGCGGCCGTCCGCGCGCTCATCCAGCGCGAAGCGGCGCGGACGCTGGCCTTGATGGGCGGCA
GCGATCCCGGCGCCACGGCGGCGCCGCGCGAGCGATCCGGCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References