31323

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 828662..829280 Replicon chromosome
Accession NZ_AP017633
Organism Helicobacter pylori strain PMSS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HPPMSS1_RS03885 Protein ID WP_077232042.1
Coordinates 828662..828922 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HPPMSS1_RS03890 Protein ID WP_077232041.1
Coordinates 828909..829280 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPPMSS1_RS03850 824483..825250 - 768 WP_000242355.1 ABC transporter ATP-binding protein -
HPPMSS1_RS03855 825250..826230 - 981 WP_077232045.1 iron ABC transporter permease -
HPPMSS1_RS03860 826223..827077 - 855 WP_103153302.1 SDR family oxidoreductase -
HPPMSS1_RS03865 827217..827741 + 525 WP_001135623.1 acyl-CoA thioesterase -
HPPMSS1_RS03870 827923..828122 - 200 Protein_749 virulence protein -
HPPMSS1_RS03875 828119..828280 - 162 WP_077232044.1 type II toxin-antitoxin system YafQ family toxin -
HPPMSS1_RS03880 828294..828584 - 291 WP_077232043.1 hypothetical protein -
HPPMSS1_RS03885 828662..828922 - 261 WP_077232042.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HPPMSS1_RS03890 828909..829280 - 372 WP_077232041.1 hypothetical protein Antitoxin
HPPMSS1_RS03895 830043..832205 - 2163 WP_077232040.1 outer membrane beta-barrel protein -
HPPMSS1_RS03910 832943..833590 + 648 Protein_755 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10250.18 Da        Isoelectric Point: 9.9512

>T31323 WP_077232042.1 NZ_AP017633:c828922-828662 [Helicobacter pylori]
MLKIRHHILFKKDFKKLVKNGFDDSVLNEVILRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVKDDELILLRLG
SHSELF

Download         Length: 261 bp

>T31323 NZ_AP017633:c828922-828662 [Helicobacter pylori]
ATGCTGAAAATTAGGCACCATATCCTTTTCAAAAAAGACTTTAAAAAACTCGTTAAAAACGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAAGAAAAAAAGAACCGCTAGATCCACAATTTCAAGATCATGCCTTAAAGGGAAAGTGGAAACCTT
TTAGGGAATGCCACATCAAAGCCGACATTTTGCTTGTGTATTTAGTGAAAGATGATGAACTGATTTTGTTAAGGTTAGGC
AGTCATAGCGAGTTGTTTTAA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 14579.46 Da        Isoelectric Point: 5.3496

>AT31323 WP_077232041.1 NZ_AP017633:c829280-828909 [Helicobacter pylori]
MPNTTAEKDYTKYSEKQLFNLIHQLERKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCL
GHEIPNIQTQQAMRDALKDENLETIEDFSAWANEIKKEVNAEN

Download         Length: 372 bp

>AT31323 NZ_AP017633:c829280-828909 [Helicobacter pylori]
ATGCCTAACACCACCGCAGAAAAAGACTACACAAAATACAGCGAAAAACAGCTTTTTAATTTAATCCATCAATTAGAGCG
AAAAATCAAAAAGATGCAAAATGATAGAGTTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGAACTCTTGCAAAAAATCAGCCAAGCTTTTGATGATAAAAGAGATTGTTGTTTG
GGGCATGAGATCCCAAACATTCAAACGCAACAAGCCATGAGAGATGCGTTAAAAGACGAAAACTTAGAAACTATTGAAGA
CTTTTCTGCATGGGCAAATGAAATCAAAAAGGAAGTGAATGCTGAAAATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References