Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1538220..1539474 Replicon chromosome
Accession NZ_AP017603
Organism Sphingopyxis sp. EG6

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag SPYCW_RS07565 Protein ID WP_197715668.1
Coordinates 1538220..1538840 (-) Length 207 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag SPYCW_RS07570 Protein ID WP_120216274.1
Coordinates 1538854..1539474 (-) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SPYCW_RS07535 1533831..1535072 + 1242 WP_120216269.1 site-specific integrase -
SPYCW_RS07540 1535069..1535506 + 438 WP_197715667.1 nuclease -
SPYCW_RS07545 1535558..1536187 + 630 WP_120216270.1 hypothetical protein -
SPYCW_RS07550 1536284..1537135 - 852 WP_172595441.1 hypothetical protein -
SPYCW_RS18960 1537132..1537395 - 264 WP_172595442.1 hypothetical protein -
SPYCW_RS07560 1537379..1538160 - 782 Protein_1497 IS5 family transposase -
SPYCW_RS07565 1538220..1538840 - 621 WP_197715668.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
SPYCW_RS07570 1538854..1539474 - 621 WP_120216274.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
SPYCW_RS07575 1539556..1541526 - 1971 WP_120218170.1 DUF4338 domain-containing protein -
SPYCW_RS07580 1541654..1543105 - 1452 WP_197715669.1 ATP-binding protein -
SPYCW_RS07585 1543131..1544381 - 1251 WP_172595571.1 glycosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1520493..1551626 31133
- flank IS/Tn - - 1532516..1533532 1016


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(31-197)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(12-92)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23204.70 Da        Isoelectric Point: 4.7380

>T31185 WP_197715668.1 NZ_AP017603:c1538840-1538220 [Sphingopyxis sp. EG6]
MAKSVKDRLLNIARQEGRVFDVLLVRFALERLLYRLSVSQHRERFVLKGGMLVTVWVEDDNRVTRDADFLGHGDPDPERL
AADFREIMAIESDDGLVFDLDALAATAIREEMEYGGTRLKTSAYLEKTRIPVTIDIGFGDAMADATQQLDYPTLLDLPAP
SVRAYPPATVIAEKFQAMVALGVLNGRMKDYYDLWAIPRALEIRPC

Download         Length: 621 bp

>T31185 NZ_AP017603:c1538840-1538220 [Sphingopyxis sp. EG6]
ATGGCCAAGTCCGTCAAGGACCGGCTGCTCAACATCGCCCGCCAGGAGGGCCGAGTGTTCGACGTTCTGTTGGTGCGGTT
CGCCTTGGAACGTCTGCTGTACCGGCTGTCGGTCTCCCAGCATCGCGAGCGTTTCGTCCTGAAGGGCGGGATGTTGGTCA
CAGTTTGGGTCGAGGACGACAACCGGGTGACCCGGGACGCGGACTTCCTGGGCCACGGCGACCCCGACCCGGAACGCCTG
GCCGCGGACTTCCGGGAGATCATGGCCATCGAGAGCGATGATGGCCTCGTCTTCGACCTCGACGCCCTGGCTGCGACAGC
CATCCGCGAGGAGATGGAATATGGCGGCACCCGCCTCAAGACTTCAGCCTATCTCGAAAAGACGCGAATCCCTGTGACGA
TCGATATCGGCTTTGGCGACGCCATGGCCGATGCGACCCAGCAACTCGACTATCCGACCTTGCTGGATCTGCCCGCGCCC
AGCGTGCGTGCCTATCCGCCCGCTACGGTGATCGCCGAGAAATTCCAGGCGATGGTCGCGCTCGGTGTCCTGAACGGACG
AATGAAGGACTACTACGATCTGTGGGCGATCCCGCGCGCGCTCGAGATTAGGCCGTGTTGA

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 22756.20 Da        Isoelectric Point: 10.1481

>AT31185 WP_120216274.1 NZ_AP017603:c1539474-1538854 [Sphingopyxis sp. EG6]
MPSAPDSQRIQLRNLLDSRSMMRAQELREAGISAQTIARAVETGEIERISRGVYQKRGSEIEENQILAEAAIRVPKGVIA
LVSALAFHGLTDQMPRRIWMAIGASDWAPVQSYPPTRMVRFTERYLRQGVENHMIAGLEVPIYSVPKTLADLFRNSKLVD
RSVAVEGLRATIEQRKATPSAIAEGAKAGGAWKIMQPYLEALTSNG

Download         Length: 621 bp

>AT31185 NZ_AP017603:c1539474-1538854 [Sphingopyxis sp. EG6]
ATGCCGTCCGCTCCGGATTCGCAAAGGATCCAACTCAGAAATCTGCTCGACAGCCGGAGCATGATGCGCGCGCAGGAACT
GCGTGAAGCTGGGATCAGCGCGCAGACCATCGCGCGCGCCGTCGAGACCGGGGAAATCGAACGTATCTCGCGCGGGGTCT
ACCAGAAGCGTGGATCCGAGATCGAGGAGAACCAGATCCTCGCCGAGGCGGCGATACGCGTCCCCAAGGGTGTGATCGCT
CTGGTGTCTGCGCTCGCCTTTCATGGCCTGACCGATCAGATGCCGCGCCGCATCTGGATGGCCATCGGCGCTAGCGACTG
GGCGCCGGTGCAGTCCTATCCCCCGACGCGCATGGTGCGGTTCACCGAGCGCTATCTGCGTCAGGGCGTCGAAAACCATA
TGATCGCTGGCCTTGAGGTCCCGATCTATTCCGTCCCCAAGACCCTTGCCGACCTCTTTCGCAACTCGAAGCTGGTTGAT
CGGTCGGTGGCGGTGGAAGGCCTGCGCGCCACCATCGAACAACGCAAGGCGACCCCGAGCGCGATCGCCGAGGGCGCGAA
AGCCGGCGGCGCGTGGAAGATCATGCAACCCTATCTCGAGGCCCTGACGTCGAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References