Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 4133416..4133918 Replicon chromosome
Accession NZ_AP017560
Organism Pseudanabaena sp. ABRG5-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ABRG53_RS18845 Protein ID WP_126388799.1
Coordinates 4133664..4133918 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ABRG53_RS18840 Protein ID WP_126388797.1
Coordinates 4133416..4133667 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABRG53_RS18810 4128793..4129677 + 885 WP_126388789.1 MBL fold metallo-hydrolase -
ABRG53_RS18815 4129842..4130966 + 1125 WP_126388791.1 type III polyketide synthase -
ABRG53_RS18820 4131080..4131832 + 753 WP_126388793.1 methyltransferase domain-containing protein -
ABRG53_RS18825 4131841..4132134 - 294 WP_126388795.1 hypothetical protein -
ABRG53_RS18830 4132227..4132595 + 369 WP_126384216.1 IS630 transposase-related protein -
ABRG53_RS18835 4132565..4133173 + 609 Protein_3737 IS630 family transposase -
ABRG53_RS18840 4133416..4133667 + 252 WP_126388797.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ABRG53_RS18845 4133664..4133918 + 255 WP_126388799.1 Txe/YoeB family addiction module toxin Toxin
ABRG53_RS18850 4133927..4135087 + 1161 WP_126388801.1 NAD(P)/FAD-dependent oxidoreductase -
ABRG53_RS18855 4135049..4136311 - 1263 WP_126388803.1 MFS transporter -
ABRG53_RS18860 4136380..4137045 - 666 WP_126388805.1 pentapeptide repeat-containing protein -
ABRG53_RS18865 4137490..4138185 + 696 WP_126388807.1 hypothetical protein -
ABRG53_RS18870 4138428..4138814 + 387 WP_126388809.1 glycine cleavage system protein GcvH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10194.68 Da        Isoelectric Point: 9.2202

>T31155 WP_126388799.1 NZ_AP017560:4133664-4133918 [Pseudanabaena sp. ABRG5-3]
VKLIFSERAWEDYLYWQKTDKKILNRINSLIKDIQRDPYSGIGKPEALKHGLSGYWSRRIDDEHRILYKVEDDALLLVQI
RYHY

Download         Length: 255 bp

>T31155 NZ_AP017560:4133664-4133918 [Pseudanabaena sp. ABRG5-3]
GTGAAGCTTATTTTTTCAGAACGTGCTTGGGAAGATTATCTTTACTGGCAAAAAACAGACAAAAAAATATTGAATCGAAT
TAATAGTCTGATTAAGGATATTCAACGAGATCCATACAGTGGTATTGGCAAGCCAGAAGCCTTAAAACATGGATTGTCGG
GATATTGGTCTAGGCGTATTGATGATGAGCATAGGATTCTTTACAAGGTTGAAGATGATGCACTTTTATTAGTTCAGATT
CGTTATCACTATTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9205.35 Da        Isoelectric Point: 4.4131

>AT31155 WP_126388797.1 NZ_AP017560:4133416-4133667 [Pseudanabaena sp. ABRG5-3]
MNAVSYVEAQSNLAKMIDQVCDNHDPVVITRHQQPSAVLLSLEDYESLAETAYLLKSRNNAKRIFEAIAELESGGGTVRE
LIE

Download         Length: 252 bp

>AT31155 NZ_AP017560:4133416-4133667 [Pseudanabaena sp. ABRG5-3]
ATGAACGCAGTTTCTTATGTTGAGGCACAGAGCAATTTAGCAAAAATGATCGATCAGGTATGTGACAATCATGATCCAGT
AGTCATAACACGCCATCAACAACCATCCGCAGTGCTTCTATCACTTGAAGATTATGAATCTCTGGCAGAAACTGCTTACC
TTTTAAAAAGTCGTAATAATGCTAAACGAATTTTTGAGGCGATCGCTGAATTAGAATCTGGTGGAGGCACTGTACGGGAG
CTAATCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References