Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1846395..1847415 Replicon chromosome
Accession NZ_AP017560
Organism Pseudanabaena sp. ABRG5-3

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag ABRG53_RS08445 Protein ID WP_126386217.1
Coordinates 1846843..1847415 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag ABRG53_RS08440 Protein ID WP_126386216.1
Coordinates 1846395..1846850 (+) Length 152 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABRG53_RS08410 1841748..1842698 + 951 WP_126386214.1 bifunctional riboflavin kinase/FAD synthetase -
ABRG53_RS08415 1842839..1843750 - 912 WP_126390136.1 VWA domain-containing protein -
ABRG53_RS08420 1843847..1844395 - 549 Protein_1671 CHAT domain-containing protein -
ABRG53_RS08425 1844921..1845529 - 609 Protein_1672 IS630 family transposase -
ABRG53_RS08430 1845499..1845867 - 369 WP_126384216.1 IS630 transposase-related protein -
ABRG53_RS08435 1845901..1846209 - 309 WP_126386215.1 hypothetical protein -
ABRG53_RS08440 1846395..1846850 + 456 WP_126386216.1 helix-turn-helix domain-containing protein Antitoxin
ABRG53_RS08445 1846843..1847415 + 573 WP_126386217.1 PIN domain-containing protein Toxin
ABRG53_RS08450 1847514..1848101 - 588 WP_126386218.1 GNAT family N-acetyltransferase -
ABRG53_RS08455 1848164..1848838 - 675 WP_126386219.1 M23 family metallopeptidase -
ABRG53_RS08460 1848995..1849642 + 648 WP_126386220.1 cytochrome b6 -
ABRG53_RS08465 1849725..1850210 + 486 WP_126386221.1 cytochrome b6-f complex subunit IV -
ABRG53_RS08470 1850321..1851946 + 1626 WP_126386222.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-114)

Antitoxin

Helix-turn-helix domain, group 17

(81-126)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21841.43 Da        Isoelectric Point: 5.0412

>T31153 WP_126386217.1 NZ_AP017560:1846843-1847415 [Pseudanabaena sp. ABRG5-3]
MTSKFTVIYDACVLYPNYLRDILIQLAITDLFRAKWTNLIHDEWIRNLIENRPDLTMEKLNQVKDLMNSQVRDSLVTDFD
QLIPSLTLPDPNDRHILAAAIVAEADIIVTFNLKDFPDVNISQYGITAKHPDDFITDLLGLNPFKVIAAVETCRQRLKKK
PKTSNEYLEILLNQGLPLSISMLKELKEML

Download         Length: 573 bp

>T31153 NZ_AP017560:1846843-1847415 [Pseudanabaena sp. ABRG5-3]
ATGACTAGCAAGTTTACAGTGATATACGATGCCTGTGTCCTTTATCCTAACTATCTTAGAGATATTCTCATTCAATTAGC
GATCACCGATCTATTTAGAGCCAAATGGACTAACTTAATTCATGACGAATGGATTCGCAATCTTATCGAAAATCGTCCTG
ATTTAACAATGGAAAAGCTAAATCAAGTCAAAGATTTGATGAATAGCCAAGTTCGAGACAGTTTAGTTACGGATTTTGAT
CAACTAATTCCATCCTTAACATTACCTGATCCTAACGATCGCCATATTCTGGCGGCAGCAATTGTGGCTGAAGCTGATAT
TATTGTCACCTTTAATTTAAAAGACTTTCCTGACGTGAATATCAGTCAGTATGGAATCACCGCAAAGCATCCAGATGATT
TTATTACCGATTTGCTTGGCTTAAATCCTTTCAAAGTTATAGCAGCAGTTGAAACTTGTCGGCAACGCTTAAAAAAGAAA
CCCAAAACTAGCAATGAATACTTAGAAATTTTGTTAAATCAGGGGCTACCACTCTCTATATCAATGCTAAAAGAACTCAA
GGAAATGTTATGA

Antitoxin


Download         Length: 152 a.a.        Molecular weight: 16886.18 Da        Isoelectric Point: 4.6596

>AT31153 WP_126386216.1 NZ_AP017560:1846395-1846850 [Pseudanabaena sp. ABRG5-3]
MVALTESLHIPTEEETEISKESSRIFASHISDGVRHLKIVEADGSEETATIPAAAYRLFIDILTEMSQGNAVTIIPIHAE
LTTQEAADLINVSRPFLIKQLEEGVIPYHKVGKHRRVRFTDLMEYKTNIDAARNKVLDEIVAISEDLGLYD

Download         Length: 456 bp

>AT31153 NZ_AP017560:1846395-1846850 [Pseudanabaena sp. ABRG5-3]
ATGGTTGCCCTAACCGAGTCTCTACACATTCCCACCGAAGAAGAAACCGAAATTTCTAAAGAAAGCAGCCGTATTTTTGC
TTCGCATATTAGCGATGGTGTCCGTCATCTCAAAATCGTAGAAGCAGATGGCAGTGAAGAAACAGCCACAATCCCTGCGG
CAGCCTATCGCCTATTTATAGACATTTTGACCGAGATGTCGCAGGGCAATGCCGTAACGATCATTCCCATCCATGCTGAA
CTAACCACCCAAGAAGCCGCAGATTTAATCAACGTCTCGCGTCCGTTCTTAATCAAACAACTAGAAGAAGGCGTAATTCC
CTATCACAAAGTCGGAAAACATCGCCGAGTTCGTTTTACTGACTTAATGGAATACAAAACAAATATTGATGCCGCTAGAA
ACAAAGTTTTAGATGAGATTGTGGCAATATCTGAAGATTTAGGACTTTATGACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References