Detailed information of TA system TA031134

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataT-KacA/DUF1778(antitoxin)
• Location: 2289361..2290155
• Replicon: chromosome
• Accession: NZ_AP017469
• Organism: Hafnia sp. CBA7124

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: CPY98_RS10520
• Protein ID: WP_096387615.1
• Coordinates: 2289634..2290155 (+)
• Length: 174 a.a.

Antitoxin (Protein)

• Gene name: KacA
• Uniprot ID: A0A097R2F1
• Locus tag: CPY98_RS10515
• Protein ID: WP_025801385.1
• Coordinates: 2289361..2289630 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPY98_RS10500	2284946..2285977	-	1032	WP_043493238.1	Mal regulon transcriptional regulator MalI	-
CPY98_RS10505	2286228..2287823	+	1596	WP_025801383.1	maltose/glucose-specific PTS transporter subunit IIBC	-
CPY98_RS10510	2287907..2289082	+	1176	WP_096387613.1	pyridoxal phosphate-dependent aminotransferase	-
CPY98_RS10515	2289361..2289630	+	270	WP_025801385.1	DUF1778 domain-containing protein	Antitoxin
CPY98_RS10520	2289634..2290155	+	522	WP_096387615.1	GNAT family N-acetyltransferase	Toxin
CPY98_RS10525	2290353..2291351	+	999	WP_096387617.1	adenosine deaminase	-
CPY98_RS10530	2292095..2293090	-	996	WP_096387618.1	bile acid:sodium symporter	-
CPY98_RS10535	2293252..2294295	-	1044	WP_096387620.1	oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (92-152)

Antitoxin

• Vibrio phage ICP1, Orf50 (3-88)

Sequences

Toxin

Protein

• Length: 174 a.a.
• Molecular weight: 19412.24 Da
• Isoelectric Point: 6.9676

>T31134 WP_096387615.1 NZ_AP017469:2289634-2290155 [Hafnia sp. CBA7124]
MPDLTIAIFSSEAEYDFSDFDCGEESLNVFLTDHLARQHNARILRGYLLITQTLKPKVVGYYTLSGSCFEKETLPSNTQK
RKVPYVNVPSITLGRLAIQKDLHGQEWGTALVTHAMQVVYRASLAVGVHGMFVDALNEKAKQFYLKLGFIALTGNNANSL
FYPTKSIEKLFED

Nucleotide

• Length: 522 bp

>T31134 NZ_AP017469:2289634-2290155 [Hafnia sp. CBA7124]
ATGCCTGACTTAACCATTGCGATTTTTTCGAGTGAGGCTGAATACGATTTCTCCGACTTTGACTGCGGCGAAGAATCCCT
GAATGTATTCCTTACCGATCATTTGGCCCGCCAGCATAATGCGCGAATTTTACGTGGCTATTTACTCATAACCCAAACGC
TAAAACCCAAAGTCGTTGGTTATTACACGCTATCTGGTAGCTGCTTCGAAAAGGAAACGCTGCCGTCAAATACCCAGAAA
CGCAAAGTGCCTTATGTCAACGTACCCAGTATCACTTTAGGGCGTCTCGCCATTCAAAAAGATCTCCATGGACAAGAATG
GGGAACGGCGCTGGTGACTCACGCGATGCAAGTGGTTTATCGAGCATCGCTTGCCGTGGGCGTTCACGGTATGTTTGTCG
ATGCACTCAATGAGAAAGCAAAGCAGTTCTACCTGAAGCTTGGATTTATCGCTCTCACGGGCAATAACGCAAACTCGCTT
TTCTACCCAACCAAATCCATCGAAAAGCTGTTCGAGGATTAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10097.51 Da
• Isoelectric Point: 5.8580

>AT31134 WP_025801385.1 NZ_AP017469:2289361-2289630 [Hafnia sp. CBA7124]
MSALKKQRIDLRLTDEDKNAIEEAAAMSNQTITQFMLTSASERAAEVIEQHRRLILSDESWNLVMDAISTPPAPNDRLKR
AAKRLQSME

Nucleotide

• Length: 270 bp

>AT31134 NZ_AP017469:2289361-2289630 [Hafnia sp. CBA7124]
ATGTCTGCATTAAAAAAACAGCGTATCGATCTTCGATTAACTGACGAAGACAAAAACGCCATTGAAGAAGCTGCGGCAAT
GTCCAACCAAACTATCACGCAGTTTATGCTTACCAGCGCCTCTGAACGTGCAGCGGAAGTTATCGAGCAACACCGTCGCT
TGATCCTCAGCGATGAGTCATGGAACCTGGTAATGGATGCCATCAGCACCCCACCGGCACCGAACGATAGACTTAAACGC
GCAGCCAAACGTCTGCAAAGTATGGAATAG

Structures

Antitoxin

• AlphaFold DB: A0A097R2F1