Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5494334..5494971 Replicon chromosome
Accession NZ_AP017423
Organism Pseudomonas sp. LAB-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LAB08_RS24850 Protein ID WP_096513877.1
Coordinates 5494564..5494971 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LAB08_RS24845 Protein ID WP_096513876.1
Coordinates 5494334..5494564 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LAB08_RS24810 5489913..5490185 + 273 WP_007897448.1 oxidative damage protection protein -
LAB08_RS24820 5490441..5490884 - 444 WP_096513871.1 hypothetical protein -
LAB08_RS24825 5491146..5492204 + 1059 WP_096513872.1 DUF1016 family protein -
LAB08_RS24830 5492273..5493247 + 975 WP_096513873.1 alpha/beta fold hydrolase -
LAB08_RS24835 5493284..5493700 + 417 WP_096513874.1 hypothetical protein -
LAB08_RS24840 5493707..5494159 + 453 WP_096513875.1 hypothetical protein -
LAB08_RS24845 5494334..5494564 + 231 WP_096513876.1 antitoxin Antitoxin
LAB08_RS24850 5494564..5494971 + 408 WP_096513877.1 tRNA(fMet)-specific endonuclease VapC Toxin
LAB08_RS24855 5495064..5496455 - 1392 WP_096513878.1 GABA permease -
LAB08_RS24860 5497018..5497791 + 774 WP_007972784.1 ABC transporter ATP-binding protein -
LAB08_RS24865 5497805..5498554 + 750 WP_096513879.1 ABC transporter substrate-binding protein -
LAB08_RS24870 5498632..5499327 + 696 WP_096513880.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15235.64 Da        Isoelectric Point: 7.9066

>T31128 WP_096513877.1 NZ_AP017423:5494564-5494971 [Pseudomonas izuensis]
MIKYMLDTNICIYTIKNKPQIVREAFNRHHDQLCISTVTLMELIYGAEKSAAPEKNLALIEGFAARLEVFSFDKEAAAHT
GMIRSELAKIGTPIGPFDQMIAGHARSRGFIVVTNNTREFERVPGLRVEDWVSPR

Download         Length: 408 bp

>T31128 NZ_AP017423:5494564-5494971 [Pseudomonas izuensis]
ATGATCAAATACATGCTGGACACCAACATCTGCATCTACACCATCAAAAACAAGCCACAGATCGTACGCGAAGCGTTCAA
TCGCCATCATGACCAGCTGTGCATTAGCACTGTCACTCTGATGGAGTTGATTTACGGTGCGGAGAAATCCGCAGCACCCG
AGAAAAACCTGGCACTCATCGAGGGATTTGCTGCTCGTCTCGAAGTTTTTTCTTTCGACAAAGAGGCGGCTGCGCATACG
GGAATGATTCGATCTGAATTGGCAAAGATCGGCACGCCAATCGGCCCCTTTGACCAAATGATTGCCGGTCACGCGCGCTC
TCGCGGCTTCATCGTGGTAACGAACAACACTCGGGAGTTCGAGCGAGTACCGGGGTTGCGGGTAGAAGACTGGGTTAGCC
CGCGCTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8557.57 Da        Isoelectric Point: 4.5184

>AT31128 WP_096513876.1 NZ_AP017423:5494334-5494564 [Pseudomonas izuensis]
MEHTTIFMSNRSQAVRLPKAVAMPSEVTRVSVIAVGRARIITPAGETWDSWFDGESVSPDFMTDREQPADQERESF

Download         Length: 231 bp

>AT31128 NZ_AP017423:5494334-5494564 [Pseudomonas izuensis]
ATGGAACACACCACCATTTTCATGAGCAATCGAAGCCAGGCAGTTCGTCTACCCAAGGCTGTAGCAATGCCCAGTGAGGT
AACACGGGTGAGCGTCATTGCCGTTGGCAGAGCCCGCATCATTACCCCTGCCGGTGAAACCTGGGATAGCTGGTTCGACG
GCGAAAGCGTTAGCCCAGACTTCATGACCGACCGCGAGCAACCCGCCGATCAGGAGCGCGAGTCGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References