Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-dnstrm_HI1420 |
Location | 1033188..1033792 | Replicon | chromosome |
Accession | NZ_AP017423 | ||
Organism | Pseudomonas sp. LAB-08 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | LAB08_RS04990 | Protein ID | WP_096509903.1 |
Coordinates | 1033499..1033792 (-) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | LAB08_RS04985 | Protein ID | WP_096509902.1 |
Coordinates | 1033188..1033496 (-) | Length | 103 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LAB08_RS04965 | 1028774..1029877 | + | 1104 | WP_096509898.1 | polyamine ABC transporter substrate-binding protein | - |
LAB08_RS04970 | 1029908..1031326 | + | 1419 | WP_096509899.1 | aminotransferase | - |
LAB08_RS04975 | 1031323..1032231 | + | 909 | WP_096509900.1 | helix-turn-helix transcriptional regulator | - |
LAB08_RS04980 | 1032365..1032679 | - | 315 | WP_096509901.1 | hypothetical protein | - |
LAB08_RS04985 | 1033188..1033496 | - | 309 | WP_096509902.1 | putative addiction module antidote protein | Antitoxin |
LAB08_RS04990 | 1033499..1033792 | - | 294 | WP_096509903.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LAB08_RS04995 | 1034176..1036230 | - | 2055 | WP_096509904.1 | phenylacetic acid degradation bifunctional protein PaaZ | - |
LAB08_RS05000 | 1036391..1037467 | - | 1077 | WP_096509905.1 | phenylacetate-CoA oxygenase/reductase subunit PaaK | - |
LAB08_RS05005 | 1037499..1038032 | - | 534 | WP_096509906.1 | phenylacetate-CoA oxygenase subunit PaaJ | - |
LAB08_RS05010 | 1038019..1038780 | - | 762 | WP_096509907.1 | phenylacetate-CoA oxygenase subunit PaaC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 10679.37 Da Isoelectric Point: 10.9498
>T31126 WP_096509903.1 NZ_AP017423:c1033792-1033499 [Pseudomonas izuensis]
MNYLVQQTATFSAWHTSIRDLRARVAIARRIERASAGNLGDIKPVGDGVSEMRVDVGAGYRIYFTMRKTVVIVLLAGGDK
SSQNADIKRAKKLAKEV
MNYLVQQTATFSAWHTSIRDLRARVAIARRIERASAGNLGDIKPVGDGVSEMRVDVGAGYRIYFTMRKTVVIVLLAGGDK
SSQNADIKRAKKLAKEV
Download Length: 294 bp
>T31126 NZ_AP017423:c1033792-1033499 [Pseudomonas izuensis]
ATGAATTATCTTGTCCAGCAAACAGCGACTTTCTCCGCATGGCACACCTCAATCCGTGATTTGCGGGCAAGGGTAGCCAT
AGCCCGTCGCATTGAACGTGCTAGCGCGGGAAATTTGGGCGATATCAAGCCAGTAGGTGATGGCGTTTCCGAAATGCGCG
TGGATGTAGGTGCCGGATACCGGATTTACTTCACGATGCGCAAGACAGTCGTCATCGTCTTGCTTGCCGGGGGCGACAAG
TCATCTCAAAACGCTGATATCAAACGTGCAAAAAAATTGGCAAAGGAGGTCTAG
ATGAATTATCTTGTCCAGCAAACAGCGACTTTCTCCGCATGGCACACCTCAATCCGTGATTTGCGGGCAAGGGTAGCCAT
AGCCCGTCGCATTGAACGTGCTAGCGCGGGAAATTTGGGCGATATCAAGCCAGTAGGTGATGGCGTTTCCGAAATGCGCG
TGGATGTAGGTGCCGGATACCGGATTTACTTCACGATGCGCAAGACAGTCGTCATCGTCTTGCTTGCCGGGGGCGACAAG
TCATCTCAAAACGCTGATATCAAACGTGCAAAAAAATTGGCAAAGGAGGTCTAG
Antitoxin
Download Length: 103 a.a. Molecular weight: 11061.53 Da Isoelectric Point: 5.5656
>AT31126 WP_096509902.1 NZ_AP017423:c1033496-1033188 [Pseudomonas izuensis]
MSQTLTTFDMAALLDSDEAISEYLSQVLADGDNEEFLRAVGYVVKARGMTQVAKDSGMGRESLYKAFAPGAKPRFNTVLK
VIHALGIDLYAQPGHVINHSNS
MSQTLTTFDMAALLDSDEAISEYLSQVLADGDNEEFLRAVGYVVKARGMTQVAKDSGMGRESLYKAFAPGAKPRFNTVLK
VIHALGIDLYAQPGHVINHSNS
Download Length: 309 bp
>AT31126 NZ_AP017423:c1033496-1033188 [Pseudomonas izuensis]
ATGAGCCAGACTTTGACGACTTTCGATATGGCGGCTCTGCTCGACAGCGATGAGGCCATCAGCGAATACCTGTCTCAGGT
ACTGGCTGATGGTGACAATGAAGAATTTCTTCGCGCCGTCGGTTACGTAGTAAAGGCTCGCGGCATGACACAGGTAGCCA
AAGATTCCGGAATGGGTCGCGAAAGCTTGTACAAGGCCTTCGCTCCAGGCGCAAAACCACGTTTCAATACGGTTTTGAAA
GTGATTCACGCGTTGGGCATCGATCTGTATGCGCAGCCGGGTCATGTCATCAATCACTCGAACTCTTGA
ATGAGCCAGACTTTGACGACTTTCGATATGGCGGCTCTGCTCGACAGCGATGAGGCCATCAGCGAATACCTGTCTCAGGT
ACTGGCTGATGGTGACAATGAAGAATTTCTTCGCGCCGTCGGTTACGTAGTAAAGGCTCGCGGCATGACACAGGTAGCCA
AAGATTCCGGAATGGGTCGCGAAAGCTTGTACAAGGCCTTCGCTCCAGGCGCAAAACCACGTTTCAATACGGTTTTGAAA
GTGATTCACGCGTTGGGCATCGATCTGTATGCGCAGCCGGGTCATGTCATCAATCACTCGAACTCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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