Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1033188..1033792 Replicon chromosome
Accession NZ_AP017423
Organism Pseudomonas sp. LAB-08

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LAB08_RS04990 Protein ID WP_096509903.1
Coordinates 1033499..1033792 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag LAB08_RS04985 Protein ID WP_096509902.1
Coordinates 1033188..1033496 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LAB08_RS04965 1028774..1029877 + 1104 WP_096509898.1 polyamine ABC transporter substrate-binding protein -
LAB08_RS04970 1029908..1031326 + 1419 WP_096509899.1 aminotransferase -
LAB08_RS04975 1031323..1032231 + 909 WP_096509900.1 helix-turn-helix transcriptional regulator -
LAB08_RS04980 1032365..1032679 - 315 WP_096509901.1 hypothetical protein -
LAB08_RS04985 1033188..1033496 - 309 WP_096509902.1 putative addiction module antidote protein Antitoxin
LAB08_RS04990 1033499..1033792 - 294 WP_096509903.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LAB08_RS04995 1034176..1036230 - 2055 WP_096509904.1 phenylacetic acid degradation bifunctional protein PaaZ -
LAB08_RS05000 1036391..1037467 - 1077 WP_096509905.1 phenylacetate-CoA oxygenase/reductase subunit PaaK -
LAB08_RS05005 1037499..1038032 - 534 WP_096509906.1 phenylacetate-CoA oxygenase subunit PaaJ -
LAB08_RS05010 1038019..1038780 - 762 WP_096509907.1 phenylacetate-CoA oxygenase subunit PaaC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-96)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10679.37 Da        Isoelectric Point: 10.9498

>T31126 WP_096509903.1 NZ_AP017423:c1033792-1033499 [Pseudomonas izuensis]
MNYLVQQTATFSAWHTSIRDLRARVAIARRIERASAGNLGDIKPVGDGVSEMRVDVGAGYRIYFTMRKTVVIVLLAGGDK
SSQNADIKRAKKLAKEV

Download         Length: 294 bp

>T31126 NZ_AP017423:c1033792-1033499 [Pseudomonas izuensis]
ATGAATTATCTTGTCCAGCAAACAGCGACTTTCTCCGCATGGCACACCTCAATCCGTGATTTGCGGGCAAGGGTAGCCAT
AGCCCGTCGCATTGAACGTGCTAGCGCGGGAAATTTGGGCGATATCAAGCCAGTAGGTGATGGCGTTTCCGAAATGCGCG
TGGATGTAGGTGCCGGATACCGGATTTACTTCACGATGCGCAAGACAGTCGTCATCGTCTTGCTTGCCGGGGGCGACAAG
TCATCTCAAAACGCTGATATCAAACGTGCAAAAAAATTGGCAAAGGAGGTCTAG

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11061.53 Da        Isoelectric Point: 5.5656

>AT31126 WP_096509902.1 NZ_AP017423:c1033496-1033188 [Pseudomonas izuensis]
MSQTLTTFDMAALLDSDEAISEYLSQVLADGDNEEFLRAVGYVVKARGMTQVAKDSGMGRESLYKAFAPGAKPRFNTVLK
VIHALGIDLYAQPGHVINHSNS

Download         Length: 309 bp

>AT31126 NZ_AP017423:c1033496-1033188 [Pseudomonas izuensis]
ATGAGCCAGACTTTGACGACTTTCGATATGGCGGCTCTGCTCGACAGCGATGAGGCCATCAGCGAATACCTGTCTCAGGT
ACTGGCTGATGGTGACAATGAAGAATTTCTTCGCGCCGTCGGTTACGTAGTAAAGGCTCGCGGCATGACACAGGTAGCCA
AAGATTCCGGAATGGGTCGCGAAAGCTTGTACAAGGCCTTCGCTCCAGGCGCAAAACCACGTTTCAATACGGTTTTGAAA
GTGATTCACGCGTTGGGCATCGATCTGTATGCGCAGCCGGGTCATGTCATCAATCACTCGAACTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References