Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 440174..440792 Replicon chromosome
Accession NZ_AP017423
Organism Pseudomonas sp. LAB-08

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag LAB08_RS02085 Protein ID WP_121104714.1
Coordinates 440487..440792 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag LAB08_RS02080 Protein ID WP_096509423.1
Coordinates 440174..440494 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LAB08_RS02060 435934..436473 - 540 WP_096509419.1 DUF1003 domain-containing protein -
LAB08_RS02065 436599..437210 - 612 WP_096509420.1 TetR/AcrR family transcriptional regulator -
LAB08_RS02070 437426..438484 + 1059 WP_096509421.1 MBL fold metallo-hydrolase -
LAB08_RS02075 438616..440133 + 1518 WP_096509422.1 amidase -
LAB08_RS02080 440174..440494 - 321 WP_096509423.1 helix-turn-helix domain-containing protein Antitoxin
LAB08_RS02085 440487..440792 - 306 WP_121104714.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LAB08_RS02090 440896..441213 - 318 WP_096509425.1 helix-turn-helix domain-containing protein -
LAB08_RS02095 441337..442299 - 963 WP_096509426.1 hypothetical protein -
LAB08_RS02105 442862..444037 - 1176 WP_096509428.1 S-type pyocin domain-containing protein -
LAB08_RS02110 444494..445000 - 507 WP_096509429.1 Bro-N domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 440174..449125 8951


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-88)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 10945.49 Da        Isoelectric Point: 9.0830

>T31124 WP_121104714.1 NZ_AP017423:c440792-440487 [Pseudomonas izuensis]
MPSDVQDVFGHALHLAQSGKKHPDAKPLKGFGGAGVLELIEDFDTNTYRAVYTVSFGSAIYVLHCFQKKSTTGIKTAQCD
IDLISKRLQAARDHAKGLKNG

Download         Length: 306 bp

>T31124 NZ_AP017423:c440792-440487 [Pseudomonas izuensis]
ATGCCCTCAGATGTACAGGATGTTTTTGGTCACGCTCTCCATCTGGCGCAAAGCGGCAAGAAGCATCCGGACGCCAAGCC
ATTGAAGGGCTTTGGAGGTGCGGGGGTTCTTGAGTTGATTGAGGACTTCGATACGAACACCTATCGTGCCGTTTACACCG
TTAGTTTTGGTAGCGCAATTTATGTTCTGCACTGCTTTCAGAAAAAGTCGACTACCGGGATCAAGACCGCGCAGTGCGAC
ATCGATCTAATCAGTAAGCGCCTTCAAGCAGCACGGGATCATGCGAAAGGATTGAAAAATGGTTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11712.69 Da        Isoelectric Point: 9.0767

>AT31124 WP_096509423.1 NZ_AP017423:c440494-440174 [Pseudomonas izuensis]
MVEIEEGSGNVYEDLGTPNASEMRVKSQLAAKIGEIIKARHLTQVQASDILGLSQPKLSEMLRGKFRGISEAKMMECLLL
LGRDVQIVVKSAPRSRKEGRLEVVFT

Download         Length: 321 bp

>AT31124 NZ_AP017423:c440494-440174 [Pseudomonas izuensis]
ATGGTTGAAATCGAAGAAGGCAGTGGGAACGTCTACGAAGACCTCGGAACACCCAACGCCAGTGAAATGCGGGTCAAATC
CCAGTTGGCTGCAAAAATTGGTGAAATCATCAAGGCTCGACATTTGACCCAGGTTCAGGCGTCAGACATTTTGGGTCTGT
CACAACCCAAGCTTTCCGAAATGCTACGTGGAAAGTTTCGGGGGATCAGTGAAGCCAAGATGATGGAGTGCCTGCTGTTG
CTTGGGCGTGACGTGCAGATCGTGGTCAAGTCGGCCCCTCGATCACGAAAAGAGGGCCGACTCGAAGTGGTCTTTACCTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References