Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsaAT/- |
Location | 860823..861300 | Replicon | chromosome |
Accession | NZ_AP017377 | ||
Organism | Staphylococcus aureus strain OC8 |
Toxin (Protein)
Gene name | TsaT | Uniprot ID | Q2G005 |
Locus tag | ATE38_RS04300 | Protein ID | WP_000052078.1 |
Coordinates | 860823..861011 (-) | Length | 63 a.a. |
Antitoxin (Protein)
Gene name | TsaA | Uniprot ID | T1Y6P8 |
Locus tag | ATE38_RS04305 | Protein ID | WP_001059690.1 |
Coordinates | 861040..861300 (-) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ATE38_RS04270 | 856864..857334 | + | 471 | WP_000824472.1 | hypothetical protein | - |
ATE38_RS04275 | 857675..858361 | + | 687 | WP_001548082.1 | thermonuclease family protein | - |
ATE38_RS04280 | 858718..858918 | + | 201 | WP_001059082.1 | cold-shock protein | - |
ATE38_RS04285 | 859414..859632 | - | 219 | WP_000005886.1 | hypothetical protein | - |
ATE38_RS04290 | 859694..859978 | - | 285 | WP_001004395.1 | hypothetical protein | - |
ATE38_RS04295 | 860066..860635 | - | 570 | WP_001106654.1 | hypothetical protein | - |
ATE38_RS04300 | 860823..861011 | - | 189 | WP_000052078.1 | hypothetical protein | Toxin |
ATE38_RS04305 | 861040..861300 | - | 261 | WP_001059690.1 | hypothetical protein | Antitoxin |
ATE38_RS04310 | 861641..861844 | + | 204 | WP_000145163.1 | sterile alpha motif-like domain-containing protein | - |
ATE38_RS04315 | 861841..862077 | - | 237 | WP_000368687.1 | hypothetical protein | - |
ATE38_RS04320 | 862302..862883 | + | 582 | WP_001140686.1 | phosphoglycerate mutase family protein | - |
ATE38_RS04325 | 862956..863573 | - | 618 | WP_000255561.1 | LysE/ArgO family amino acid transporter | - |
ATE38_RS04330 | 863728..864222 | - | 495 | WP_000569884.1 | GNAT family N-acetyltransferase | - |
ATE38_RS04335 | 864621..865043 | - | 423 | WP_000974460.1 | organic hydroperoxide resistance protein | - |
ATE38_RS04340 | 865191..865907 | + | 717 | WP_000150017.1 | type I 3-dehydroquinate dehydratase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 7172.84 Da Isoelectric Point: 9.9971
>T31105 WP_000052078.1 NZ_AP017377:c861011-860823 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTSKESKKESYLSFTVILYIFGFAILIYTFIFGVL
MSLHFAILFWLALIFLVAATFILVLMKKTSKESKKESYLSFTVILYIFGFAILIYTFIFGVL
Download Length: 189 bp
>T31105 NZ_AP017377:c861011-860823 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTAGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTAGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9940.09 Da Isoelectric Point: 4.0624
>AT31105 WP_001059690.1 NZ_AP017377:c861300-861040 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
Download Length: 261 bp
>AT31105 NZ_AP017377:c861300-861040 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0D6HZ40 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VN56 |