Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 76516..77149 Replicon plasmid plasmid1 DNA
Accession NZ_AP017376
Organism Stanieria sp. NIES-3757

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag STA3757_RS24245 Protein ID WP_096388320.1
Coordinates 76754..77149 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID K9Y1V0
Locus tag STA3757_RS24240 Protein ID WP_015211880.1
Coordinates 76516..76764 (+) Length 83 a.a.

Genomic Context

STA3757_RS24240STA3757_RS24245STA3757_RS24250STA3757_RS24255STA3757_RS24260STA3757_RS24265STA3757_RS24270STA3757_RS24225STA3757_RS24230STA3757_RS24235STA3757_RS24275STA3757_RS24280STA3757_RS24285
Location: 76516..76764 (249 bp)
Type: Antitoxin
Protein ID: WP_015211880.1
Location: 76754..77149 (396 bp)
Type: Toxin
Protein ID: WP_096388320.1
Location: 77286..77543 (258 bp)
Type: Others
Protein ID: Protein_74
Location: 77543..78034 (492 bp)
Type: Others
Protein ID: WP_096388322.1
Location: 78060..78701 (642 bp)
Type: Others
Protein ID: WP_096388324.1
Location: 78879..79832 (954 bp)
Type: Others
Protein ID: WP_096388326.1
Location: 79965..80780 (816 bp)
Type: Others
Protein ID: WP_096388328.1
Location: 73517..74149 (633 bp)
Type: Others
Protein ID: WP_096388314.1
Location: 74220..75623 (1404 bp)
Type: Others
Protein ID: WP_096388316.1
Location: 75620..76294 (675 bp)
Type: Others
Protein ID: WP_096388318.1
Location: 80788..81294 (507 bp)
Type: Others
Protein ID: WP_096383530.1
Location: 81260..81607 (348 bp)
Type: Others
Protein ID: WP_096387865.1
Location: 81696..81947 (252 bp)
Type: Others
Protein ID: WP_071882437.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
STA3757_RS2422573517..74149-633WP_096388314.1tyrosine-type recombinase/integrase-
STA3757_RS2423074220..75623-1404WP_096388316.1ISKra4 family transposase-
STA3757_RS2423575620..76294-675WP_096388318.1plasmid pRiA4b ORF-3 family protein-
STA3757_RS2424076516..76764+249WP_015211880.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
STA3757_RS2424576754..77149+396WP_096388320.1type II toxin-antitoxin system VapC family toxinToxin
STA3757_RS2425077286..77543+258Protein_74hypothetical protein-
STA3757_RS2425577543..78034+492WP_096388322.1hypothetical protein-
STA3757_RS2426078060..78701+642WP_096388324.1hypothetical protein-
STA3757_RS2426578879..79832+954WP_096388326.1tyrosine-type recombinase/integrase-
STA3757_RS2427079965..80780+816WP_096388328.1hypothetical protein-
STA3757_RS2427580788..81294-507WP_096383530.1transposase-
STA3757_RS2428081260..81607-348WP_096387865.1transposase-
STA3757_RS2428581696..81947-252WP_071882437.1WGR domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..143540143540


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-80)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14361.42 Da        Isoelectric Point: 4.4076

>T31103 WP_096388320.1 NZ_AP017376:76754-77149 [Stanieria sp. NIES-3757]
MVIDTSAIIAILNLEPEATILADGIASDSVRLMSMGTALELSIIVKARKEEAGIRELDFFLYKAAINLVNFDENQLKIAR
YAFENYGKGRNPASLNFGDCFAYALSKTSGQPLLFKGNDFNQTDVSVAVEF

Download         Length: 396 bp

>T31103 NZ_AP017376:76754-77149 [Stanieria sp. NIES-3757]
ATGGTTATTGATACGAGTGCGATTATAGCGATTCTTAATCTTGAACCTGAAGCAACTATCTTAGCTGATGGAATCGCTTC
GGACTCAGTTCGTCTTATGTCTATGGGAACTGCCTTAGAACTATCAATAATAGTTAAGGCGAGAAAAGAAGAAGCTGGAA
TTAGAGAATTAGATTTCTTTTTATATAAAGCAGCCATTAATTTAGTCAATTTTGATGAAAATCAACTAAAAATAGCTCGT
TATGCTTTTGAGAATTATGGTAAAGGCAGAAATCCCGCCAGTTTAAATTTTGGTGATTGTTTTGCTTATGCTCTTAGTAA
AACTTCTGGACAACCCTTATTGTTCAAAGGTAATGATTTTAACCAAACTGATGTTTCAGTAGCAGTTGAATTTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9427.65 Da        Isoelectric Point: 4.3822

>AT31103 WP_015211880.1 NZ_AP017376:76516-76764 [Stanieria sp. NIES-3757]
MAINIKNVEADRLARELSEITGETITEAVIKSLAERLEREKNKQITPLPLQQELLNIAQRYQTLPTLDNRTEEEILGYND
GY

Download         Length: 249 bp

>AT31103 NZ_AP017376:76516-76764 [Stanieria sp. NIES-3757]
ATGGCGATTAATATTAAAAACGTTGAAGCAGATAGACTGGCTAGGGAATTAAGCGAAATAACTGGAGAAACAATCACAGA
AGCTGTAATTAAATCTTTGGCTGAAAGACTAGAAAGGGAAAAAAATAAACAAATTACTCCTTTGCCTTTACAACAAGAAC
TACTAAATATTGCTCAACGGTATCAAACCCTGCCGACTTTAGATAACCGAACAGAGGAAGAAATTTTGGGTTACAACGAT
GGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBK9Y1V0

References