Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 5185216..5185771 Replicon chromosome
Accession NZ_AP017375
Organism Stanieria sp. NIES-3757

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag STA3757_RS23235 Protein ID WP_096387452.1
Coordinates 5185216..5185554 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag STA3757_RS23240 Protein ID WP_096387454.1
Coordinates 5185544..5185771 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STA3757_RS23215 5181101..5182897 - 1797 WP_096387444.1 aspartate--tRNA ligase -
STA3757_RS23220 5183062..5183598 - 537 WP_096387446.1 Ycf51 family protein -
STA3757_RS23225 5183784..5184041 - 258 WP_096387448.1 hypothetical protein -
STA3757_RS23230 5184110..5185075 - 966 WP_096387450.1 hydroxymethylbilane synthase -
STA3757_RS23235 5185216..5185554 - 339 WP_096387452.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
STA3757_RS23240 5185544..5185771 - 228 WP_096387454.1 hypothetical protein Antitoxin
STA3757_RS23245 5185923..5188400 + 2478 WP_096387455.1 single-stranded-DNA-specific exonuclease RecJ -
STA3757_RS23250 5188560..5189021 - 462 WP_096387457.1 SRPBCC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12958.86 Da        Isoelectric Point: 9.1186

>T31101 WP_096387452.1 NZ_AP017375:c5185554-5185216 [Stanieria sp. NIES-3757]
MKCRRGEIWWVDLDPTKGKEAKKIRACLIIQNDIGNEESDLTTVVPFLSPKHYPFVVNVKPSESNQLDKERGLHFNQIRS
IDSSRLKSKLGTLESDYFSQIKRALDIQFGFF

Download         Length: 339 bp

>T31101 NZ_AP017375:c5185554-5185216 [Stanieria sp. NIES-3757]
ATGAAATGTAGACGAGGCGAAATTTGGTGGGTAGATCTCGATCCGACAAAGGGAAAAGAAGCGAAGAAAATAAGAGCTTG
TTTGATTATTCAAAATGATATTGGTAATGAAGAAAGCGATCTGACTACGGTAGTTCCTTTTCTGAGTCCGAAACACTATC
CTTTTGTTGTCAACGTAAAACCAAGCGAGTCAAATCAGTTGGATAAAGAAAGAGGACTGCATTTTAATCAAATTAGGTCA
ATTGATTCTTCTCGCCTTAAATCGAAGCTTGGCACTTTAGAATCAGATTATTTCAGTCAAATTAAAAGAGCCTTAGATAT
TCAATTCGGATTTTTCTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8925.87 Da        Isoelectric Point: 4.1849

>AT31101 WP_096387454.1 NZ_AP017375:c5185771-5185544 [Stanieria sp. NIES-3757]
MTAKITINIDDRAFEFLKQVTNNRSAYINNLLLEKEREQLEDKLREAYREQNQDTEFQQSIKDWDVTVGDGLDEM

Download         Length: 228 bp

>AT31101 NZ_AP017375:c5185771-5185544 [Stanieria sp. NIES-3757]
ATGACAGCCAAGATTACCATTAATATAGACGATCGCGCATTTGAGTTTTTAAAGCAAGTTACTAATAACCGCAGTGCATA
TATCAATAACTTGCTGTTAGAGAAAGAGCGAGAACAGTTAGAAGACAAGTTAAGAGAAGCATATCGAGAACAAAACCAAG
ATACTGAGTTTCAGCAGTCAATCAAAGATTGGGATGTTACGGTAGGGGATGGTTTGGATGAAATGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References