Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 3848478..3849034 Replicon chromosome
Accession NZ_AP017375
Organism Stanieria sp. NIES-3757

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag STA3757_RS17330 Protein ID WP_096385205.1
Coordinates 3848729..3849034 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag STA3757_RS17325 Protein ID WP_096385204.1
Coordinates 3848478..3848732 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STA3757_RS17310 3844889..3845905 - 1017 WP_096385201.1 methyltransferase -
STA3757_RS17315 3845938..3846408 - 471 WP_096385202.1 hypothetical protein -
STA3757_RS17320 3846563..3848287 - 1725 WP_096385203.1 mechanosensitive ion channel family protein -
STA3757_RS17325 3848478..3848732 + 255 WP_096385204.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
STA3757_RS17330 3848729..3849034 + 306 WP_096385205.1 Txe/YoeB family addiction module toxin Toxin
STA3757_RS17335 3849053..3849964 + 912 WP_096388054.1 HipA domain-containing protein -
STA3757_RS17340 3849964..3850725 + 762 WP_096385206.1 DNA-binding protein -
STA3757_RS17345 3850895..3851440 - 546 WP_096385207.1 DoxX family protein -
STA3757_RS17350 3851713..3853173 - 1461 WP_096385208.1 NAD(P)/FAD-dependent oxidoreductase -
STA3757_RS17355 3853362..3853838 + 477 WP_096385209.1 DM13 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(34-101)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 12259.05 Da        Isoelectric Point: 10.0426

>T31100 WP_096385205.1 NZ_AP017375:3848729-3849034 [Stanieria sp. NIES-3757]
MKLIFAEKAWEDYLYWQRCDPAPTQGARERATRQQTDKKILKRINTLIRDIQRNPFEGIGDPEPLKYNWSGFWSRRITKE
HRLVYAVEKDAILIAQYRFHY

Download         Length: 306 bp

>T31100 NZ_AP017375:3848729-3849034 [Stanieria sp. NIES-3757]
ATGAAGCTGATATTTGCTGAAAAAGCCTGGGAAGATTATTTATATTGGCAGCGTTGCGACCCCGCGCCGACGCAAGGCGC
AAGGGAACGCGCAACAAGACAGCAAACAGATAAAAAAATTCTCAAGCGTATCAATACCCTCATTAGAGATATTCAGAGAA
ATCCTTTTGAAGGAATTGGCGACCCCGAACCACTAAAATATAATTGGTCTGGCTTTTGGTCGAGAAGAATTACTAAAGAA
CATCGACTTGTTTATGCAGTAGAAAAAGATGCAATATTAATTGCTCAATATAGATTTCATTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9492.62 Da        Isoelectric Point: 4.5994

>AT31100 WP_096385204.1 NZ_AP017375:3848478-3848732 [Stanieria sp. NIES-3757]
MDTVTYTEFRQKLAGYLNKIEADRTPLIVTRQNAPSVVVMSLDDFKAYEATFHLLSSKNNADRLNNAIDELRSGGGTERE
LIEE

Download         Length: 255 bp

>AT31100 NZ_AP017375:3848478-3848732 [Stanieria sp. NIES-3757]
ATGGATACAGTTACCTATACAGAATTTAGGCAAAAATTAGCTGGATATCTCAACAAAATAGAAGCAGACCGCACCCCATT
GATTGTAACTAGGCAAAATGCACCATCAGTAGTAGTGATGAGCTTGGATGATTTTAAAGCTTATGAAGCTACTTTTCATT
TATTGTCTAGTAAAAATAATGCAGATCGATTAAATAATGCGATCGATGAACTTCGTTCTGGAGGTGGCACAGAACGAGAA
TTAATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References