Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-RelB
Location 1373985..1374489 Replicon chromosome
Accession NZ_AP017375
Organism Stanieria sp. NIES-3757

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag STA3757_RS06205 Protein ID WP_096382258.1
Coordinates 1373985..1374242 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag STA3757_RS06210 Protein ID WP_096382261.1
Coordinates 1374226..1374489 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STA3757_RS06185 1370234..1371907 - 1674 WP_096382248.1 potassium-transporting ATPase subunit A -
STA3757_RS06190 1372196..1372540 - 345 WP_096382250.1 type II toxin-antitoxin system PemK/MazF family toxin -
STA3757_RS06195 1372522..1372755 - 234 WP_096382253.1 ribbon-helix-helix domain-containing protein -
STA3757_RS06200 1372880..1373977 + 1098 WP_096382256.1 HAMP domain-containing histidine kinase -
STA3757_RS06205 1373985..1374242 - 258 WP_096382258.1 Txe/YoeB family addiction module toxin Toxin
STA3757_RS06210 1374226..1374489 - 264 WP_096382261.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
STA3757_RS06215 1374560..1375207 + 648 WP_096382263.1 response regulator transcription factor -
STA3757_RS06220 1375380..1376594 + 1215 WP_096382266.1 sodium:proton antiporter -
STA3757_RS06225 1376787..1377176 + 390 WP_096382268.1 response regulator -
STA3757_RS06230 1377500..1378849 + 1350 WP_096382271.1 CHAT domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10062.79 Da        Isoelectric Point: 10.5397

>T31099 WP_096382258.1 NZ_AP017375:c1374242-1373985 [Stanieria sp. NIES-3757]
MGWKIEFSRQALKDAKKLKAANLQENVLQLIAIIKQNPYQPSYEKLLGNLKGYYSRRINIKHRLIYSLNDVTKTIRIISV
WSHYE

Download         Length: 258 bp

>T31099 NZ_AP017375:c1374242-1373985 [Stanieria sp. NIES-3757]
ATGGGATGGAAGATTGAATTTAGCCGTCAAGCGTTGAAAGATGCTAAAAAATTGAAAGCTGCTAATTTACAAGAGAATGT
TCTACAACTGATTGCAATTATAAAACAAAACCCCTATCAACCTTCCTATGAAAAATTATTGGGTAACTTAAAAGGTTACT
ATTCAAGGAGAATTAATATTAAGCATCGTCTGATTTATTCTTTGAATGATGTTACTAAAACGATTAGAATTATTTCTGTT
TGGTCGCACTATGAATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9939.17 Da        Isoelectric Point: 4.1283

>AT31099 WP_096382261.1 NZ_AP017375:c1374489-1374226 [Stanieria sp. NIES-3757]
MDILSASEARANLFSLLEQVNKDHLPKVITSRKGDAVLVSKEDWETLQETLYLQSLPGLVRSIKEAEEADDWVSEEEFMR
KLDGMED

Download         Length: 264 bp

>AT31099 NZ_AP017375:c1374489-1374226 [Stanieria sp. NIES-3757]
ATGGATATTCTTAGCGCAAGTGAAGCTAGAGCTAATTTATTTAGTTTATTAGAACAAGTTAATAAAGACCATTTACCAAA
AGTCATTACCAGTAGAAAAGGCGATGCTGTTTTAGTCTCTAAAGAAGATTGGGAAACTTTACAAGAAACACTTTATTTAC
AATCTTTACCTGGTTTAGTGCGATCTATTAAAGAAGCCGAAGAAGCGGATGATTGGGTATCTGAGGAAGAATTTATGAGG
AAATTAGATGGGATGGAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References