Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 733532..734292 Replicon chromosome
Accession NZ_AP017375
Organism Stanieria sp. NIES-3757

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag STA3757_RS03365 Protein ID WP_096380906.1
Coordinates 733532..734038 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag STA3757_RS03370 Protein ID WP_096380910.1
Coordinates 734026..734292 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STA3757_RS03330 729516..729605 + 90 Protein_659 transposase -
STA3757_RS03335 729776..730702 - 927 WP_096380900.1 nucleoside hydrolase -
STA3757_RS03340 730728..731120 - 393 WP_096387731.1 metalloregulator ArsR/SmtB family transcription factor -
STA3757_RS03345 731186..731347 - 162 WP_096380903.1 metallothionein -
STA3757_RS03355 732032..733089 + 1058 Protein_663 IS4 family transposase -
STA3757_RS03360 733091..733378 + 288 Protein_664 IS4 family transposase -
STA3757_RS03365 733532..734038 - 507 WP_096380906.1 GNAT family N-acetyltransferase Toxin
STA3757_RS03370 734026..734292 - 267 WP_096380910.1 DUF1778 domain-containing protein Antitoxin
STA3757_RS03375 734420..735175 + 756 WP_096387733.1 IS982 family transposase -
STA3757_RS03380 735580..735816 + 237 WP_096380913.1 hypothetical protein -
STA3757_RS03385 736131..736451 + 321 WP_096380917.1 hypothetical protein -
STA3757_RS03395 737781..738284 + 504 WP_096380920.1 DNA recombination-mediator protein A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(53-146)

Antitoxin

Vibrio phage ICP1, Orf50

(4-88)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18463.37 Da        Isoelectric Point: 7.7464

>T31098 WP_096380906.1 NZ_AP017375:c734038-733532 [Stanieria sp. NIES-3757]
MGTVNYSPPQRISSEHIITDFDCGEESLNEWLKKRALKNDVADASRTYVVCCDNVVVAYYSLHLGCVQHSEAVGKIKRNM
PDPIPAIVLGRLAVDVNHQGQGLAHDLMKDMFLRAIAVSDLAGTKAVLVKALNDKVSTFYQSFGFIQSKTDPLLLMKAVA
EVKASLKQ

Download         Length: 507 bp

>T31098 NZ_AP017375:c734038-733532 [Stanieria sp. NIES-3757]
TTGGGAACAGTAAACTATTCACCACCGCAACGCATTTCTTCAGAGCATATTATTACAGACTTCGATTGTGGTGAAGAATC
ACTCAATGAATGGCTGAAGAAACGTGCGCTTAAAAATGACGTAGCAGATGCTAGTAGAACCTATGTTGTCTGCTGTGACA
ATGTAGTAGTAGCGTATTATTCGCTTCACCTAGGTTGTGTTCAACATTCCGAAGCAGTAGGGAAAATTAAACGTAATATG
CCCGATCCTATACCCGCTATCGTTTTAGGTAGGTTAGCGGTTGATGTTAATCATCAAGGTCAAGGATTAGCTCACGACTT
GATGAAAGATATGTTTCTTAGAGCCATTGCGGTTTCGGATTTGGCTGGTACTAAAGCAGTGTTGGTTAAAGCTCTTAATG
ATAAGGTAAGTACTTTTTATCAGTCTTTTGGGTTCATACAGTCTAAAACTGACCCGCTTTTATTAATGAAAGCAGTAGCT
GAAGTTAAAGCTAGCTTAAAACAATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10418.85 Da        Isoelectric Point: 4.9167

>AT31098 WP_096380910.1 NZ_AP017375:c734292-734026 [Stanieria sp. NIES-3757]
MGAMQKQKVVNLRVEESRQNLIDEAARLQGKSRTEFMIEAAYKEAEQTILDQKIFILDEADYEYLTRTDHQADPKLVKLF
ERKSLWEQ

Download         Length: 267 bp

>AT31098 NZ_AP017375:c734292-734026 [Stanieria sp. NIES-3757]
ATGGGAGCTATGCAGAAACAAAAAGTAGTCAACCTCAGAGTTGAAGAAAGCAGACAAAATCTAATAGATGAAGCAGCAAG
GCTTCAAGGTAAATCTCGCACTGAGTTTATGATAGAAGCTGCTTACAAAGAAGCCGAACAAACTATCTTAGACCAAAAGA
TTTTTATTCTAGATGAAGCTGACTATGAGTATCTGACACGTACAGATCATCAAGCCGATCCTAAGTTAGTAAAATTGTTT
GAGAGAAAAAGCCTTTGGGAACAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References