Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 700243..700805 Replicon chromosome
Accession NZ_AP017375
Organism Stanieria sp. NIES-3757

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag STA3757_RS03150 Protein ID WP_096380801.1
Coordinates 700243..700581 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag STA3757_RS03155 Protein ID WP_096387725.1
Coordinates 700581..700805 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STA3757_RS03125 695367..696143 + 777 WP_096380785.1 SAM-dependent chlorinase/fluorinase -
STA3757_RS03130 696205..696792 + 588 WP_096380788.1 DUF3038 domain-containing protein -
STA3757_RS03135 696911..698347 + 1437 WP_096380790.1 DUF4335 domain-containing protein -
STA3757_RS03140 698753..699469 - 717 WP_096380794.1 precorrin-2 C(20)-methyltransferase -
STA3757_RS03145 699466..700098 - 633 WP_096380797.1 precorrin-8X methylmutase -
STA3757_RS03150 700243..700581 - 339 WP_096380801.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
STA3757_RS03155 700581..700805 - 225 WP_096387725.1 CopG family transcriptional regulator Antitoxin
STA3757_RS03160 700988..701383 - 396 WP_096380805.1 type II toxin-antitoxin system VapC family toxin -
STA3757_RS03165 701370..701633 - 264 WP_096380809.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
STA3757_RS03170 701736..702959 + 1224 WP_096380812.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
STA3757_RS03175 703274..703609 + 336 WP_096380816.1 cation:proton antiporter subunit C -
STA3757_RS03180 703606..705042 + 1437 WP_096380820.1 cation:proton antiporter -
STA3757_RS03185 705039..705461 + 423 WP_096380824.1 Na+/H+ antiporter subunit E -
STA3757_RS03190 705510..705761 + 252 WP_096380827.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12939.11 Da        Isoelectric Point: 9.6868

>T31097 WP_096380801.1 NZ_AP017375:c700581-700243 [Stanieria sp. NIES-3757]
MNYRQLEIRWIDLEPTRGAEIQKTRPCVIIQADIVNQNSQTVIVAPLLPGHKNWLFAVNVFPTTNNGLDKERHINLKQLR
AVDISRIKNLQGILEQEYLKPIQEAIKIIFAI

Download         Length: 339 bp

>T31097 NZ_AP017375:c700581-700243 [Stanieria sp. NIES-3757]
ATGAATTATCGGCAGCTAGAAATAAGATGGATTGACTTAGAACCAACTAGAGGTGCAGAAATCCAAAAAACAAGACCATG
CGTTATTATACAAGCTGATATTGTTAACCAAAATTCTCAAACAGTTATTGTAGCTCCTCTTCTTCCGGGACATAAAAATT
GGCTCTTTGCTGTTAATGTTTTCCCCACTACAAACAACGGACTAGATAAAGAACGACATATCAATCTCAAGCAGTTAAGA
GCAGTTGATATTTCTAGAATTAAAAATTTACAAGGAATTCTGGAACAGGAATATTTAAAACCGATTCAGGAAGCTATCAA
AATAATTTTTGCAATTTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8490.43 Da        Isoelectric Point: 4.0941

>AT31097 WP_096387725.1 NZ_AP017375:c700805-700581 [Stanieria sp. NIES-3757]
MTNRATITLDDDAFAFLEARAEGNRSAYINRLLKEEKQRMIQQQILKANQEEASDLAYQEELADWDVTLSDGLI

Download         Length: 225 bp

>AT31097 NZ_AP017375:c700805-700581 [Stanieria sp. NIES-3757]
ATGACTAATCGTGCAACTATTACTCTTGATGATGATGCCTTCGCTTTTTTAGAAGCTAGAGCAGAAGGAAATCGTAGTGC
TTATATCAACCGTCTTCTCAAAGAAGAAAAACAGCGAATGATCCAGCAACAAATTTTAAAAGCTAATCAAGAAGAAGCAT
CAGATCTGGCTTATCAAGAAGAACTTGCTGATTGGGATGTAACATTATCTGATGGCTTAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References