Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2537529..2538160 Replicon chromosome
Accession NZ_AP017372
Organism Halorhodospira halochloris strain DSM 1059

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HH1059_RS11635 Protein ID WP_096406175.1
Coordinates 2537759..2538160 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HH1059_RS11630 Protein ID WP_096406173.1
Coordinates 2537529..2537759 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HH1059_RS11605 2533553..2534065 - 513 WP_162549534.1 hypothetical protein -
HH1059_RS11610 2534193..2534963 + 771 WP_096406162.1 molybdate ABC transporter substrate-binding protein -
HH1059_RS11615 2534987..2535676 + 690 WP_096406165.1 molybdate ABC transporter permease subunit -
HH1059_RS11620 2535676..2536743 + 1068 WP_096406167.1 molybdenum ABC transporter ATP-binding protein -
HH1059_RS11625 2536826..2537431 + 606 WP_096406170.1 nitrogen fixation protein NifQ -
HH1059_RS11630 2537529..2537759 + 231 WP_096406173.1 antitoxin Antitoxin
HH1059_RS11635 2537759..2538160 + 402 WP_096406175.1 tRNA(fMet)-specific endonuclease VapC Toxin
HH1059_RS11640 2538285..2538761 - 477 WP_096406178.1 single-stranded DNA-binding protein -
HH1059_RS13555 2538864..2539052 - 189 WP_162549535.1 hypothetical protein -
HH1059_RS11645 2539185..2542034 + 2850 WP_096406181.1 excinuclease ABC subunit UvrA -
HH1059_RS11650 2542099..2542569 + 471 WP_162549536.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14889.02 Da        Isoelectric Point: 6.7209

>T31095 WP_096406175.1 NZ_AP017372:2537759-2538160 [Halorhodospira halochloris]
MLKYMLDTNIAIYTIKNRPQEVREEFKAHDGQMCISAVSLMELIYGAEASAAVDRNLRDIEGFAARLEVLNYDNDAAVHT
GQLRAELRKVGRPIGPYDEMIAGHARSKGLVVVTNNTKQFENVPGIRLANWVN

Download         Length: 402 bp

>T31095 NZ_AP017372:2537759-2538160 [Halorhodospira halochloris]
ATGCTGAAGTACATGCTCGATACGAATATCGCCATTTATACCATCAAGAATCGCCCACAGGAGGTTCGAGAGGAATTTAA
GGCGCATGACGGTCAGATGTGTATTTCGGCCGTCTCCCTGATGGAGCTTATATACGGTGCGGAGGCCTCTGCGGCTGTTG
ATCGAAACTTACGCGACATAGAAGGGTTTGCCGCTCGCCTTGAAGTCCTTAACTATGACAACGATGCGGCTGTGCATACC
GGGCAGCTTCGGGCCGAGCTTAGGAAAGTGGGCCGACCTATTGGTCCATACGATGAAATGATCGCTGGCCACGCCCGCTC
AAAAGGTTTGGTTGTTGTTACGAACAATACAAAGCAGTTTGAAAACGTGCCAGGCATACGCTTGGCAAACTGGGTGAATT
GA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8778.88 Da        Isoelectric Point: 5.0644

>AT31095 WP_096406173.1 NZ_AP017372:2537529-2537759 [Halorhodospira halochloris]
MERVSIFKSNKSQALRLPKPVAYPETVRQVDIFILGRTRIITPAGESWDTWFESDGVSDDFMTSREQPGHQEREPL

Download         Length: 231 bp

>AT31095 NZ_AP017372:2537529-2537759 [Halorhodospira halochloris]
ATGGAGCGAGTAAGCATCTTCAAAAGCAACAAAAGTCAGGCATTACGGCTCCCAAAGCCCGTAGCTTACCCTGAGACGGT
TAGGCAGGTAGACATTTTTATCCTGGGCCGCACCAGGATCATTACTCCGGCTGGCGAGTCATGGGATACCTGGTTCGAGA
GTGACGGCGTTTCCGACGATTTCATGACAAGTCGTGAGCAGCCGGGCCACCAAGAGCGTGAGCCCCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References