Detailed information of TA system TA031094

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 2206486..2206955
• Replicon: chromosome
• Accession: NZ_AP017372
• Organism: Halorhodospira halochloris strain DSM 1059

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HH1059_RS09950
• Protein ID: WP_096410011.1
• Coordinates: 2206486..2206707 (-)
• Length: 74 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HH1059_RS09955
• Protein ID: WP_096410012.1
• Coordinates: 2206704..2206955 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HH1059_RS09935	2201554..2204997	-	3444	WP_096410008.1	pyruvate carboxylase	-
HH1059_RS13485	2205140..2205304	+	165	WP_162549499.1	hypothetical protein	-
HH1059_RS09940	2205645..2205941	+	297	WP_096410009.1	hypothetical protein	-
HH1059_RS09945	2205978..2206529	-	552	WP_096410010.1	RNA 2',3'-cyclic phosphodiesterase	-
HH1059_RS09950	2206486..2206707	-	222	WP_096410011.1	Txe/YoeB family addiction module toxin	Toxin
HH1059_RS09955	2206704..2206955	-	252	WP_096410012.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HH1059_RS09960	2207933..2209705	+	1773	WP_096410013.1	DUF262 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-53)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 74 a.a.
• Molecular weight: 8556.93 Da
• Isoelectric Point: 10.6919

>T31094 WP_096410011.1 NZ_AP017372:c2206707-2206486 [Halorhodospira halochloris]
MKLIFSENAWEDYLYWQKTDKKILNRINRLIKEIKREPFEGVGKPEPLKHSSTARRVNPYGSASTPLLRAVAR

Nucleotide

• Length: 222 bp

>T31094 NZ_AP017372:c2206707-2206486 [Halorhodospira halochloris]
ATGAAGCTCATCTTCTCTGAGAACGCCTGGGAGGACTATCTGTACTGGCAGAAAACCGACAAAAAGATTCTTAACCGAAT
CAACAGGCTGATCAAAGAGATTAAGCGAGAACCATTTGAAGGTGTTGGCAAACCAGAGCCCCTCAAACACAGCTCGACTG
CGCGTCGTGTGAACCCATATGGATCGGCGTCAACGCCTCTTCTTCGCGCTGTGGCCAGATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9243.51 Da
• Isoelectric Point: 4.5959

>AT31094 WP_096410012.1 NZ_AP017372:c2206955-2206704 [Halorhodospira halochloris]
MDAISYTAARANLAKTMEQVCEDHSPVIITRSKSQSVVMISLEDYEALQETAYLLRAPKNARRLLESVVELEQGGGQEKA
LFE

Nucleotide

• Length: 252 bp

>AT31094 NZ_AP017372:c2206955-2206704 [Halorhodospira halochloris]
ATGGATGCCATTAGCTACACAGCTGCCAGAGCCAATCTAGCAAAAACCATGGAGCAGGTCTGTGAAGACCACTCTCCTGT
GATCATCACTCGGAGCAAGTCGCAGTCCGTGGTAATGATCTCCCTGGAGGATTACGAGGCGCTGCAAGAAACTGCATACC
TACTGCGCGCACCAAAGAACGCTCGGCGTTTGCTGGAATCCGTCGTAGAGTTGGAGCAAGGCGGTGGTCAAGAAAAGGCA
CTTTTTGAATGA